I-Febuxostat

-Delile

• Ngaphambi kokuthatha i-febuxostat,
• I-Febuxostat ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Abantu abathatha i-febuxostat bangaba sengozini enkulu yokufa okuhlobene nenhliziyo kunabantu abathatha eminye imithi yokwelapha i-gout. Tshela udokotela wakho uma uke waba nesifo senhliziyo noma isifo senhliziyo noma isifo sohlangothi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu besifuba, ukuphefumula, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuba ndikindiki noma ukubuthakathaka kolunye uhlangothi lomzimba wakho, isiyezi, ukuquleka, ukukhuluma okungaqondakali, ukubona okungazelelwe okufiphele, noma ukuzuma okukhulu okungazelelwe ikhanda.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-febuxostat futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-febuxostat.

I-Febuxostat isetshenziselwa ukwelapha i-gout kubantu abadala abangazange belashwe ngempumelelo noma abangakwazi ukuthatha i-allopurinol (Aloprim, Zyloprim). I-Gout uhlobo lwesifo samathambo lapho i-uric acid, into eyenzeka ngokwemvelo emzimbeni, yakhela emalungeni futhi idale ukuhlaselwa okungazelelwe kokubomvu, ukuvuvukala, izinhlungu nokushisa kwilunga elilodwa noma amaningi. UFebuxostat usesigabeni semithi ebizwa nge-xanthine oxidase inhibitors. Isebenza ngokunciphisa inani le-uric acid elenziwe emzimbeni. I-Febuxostat isetshenziselwa ukuvikela ukuhlaselwa yi-gout kodwa hhayi ukuyelapha uma seyenzekile.

I-Febuxostat iza njenge-tablet ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-febuxostat ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-febuxostat njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakhuphula umthamo wakho we-febuxostat ngemuva kwamasonto amabili uma ukuhlolwa kwelabhoratri kukhombisa ukuthi usene-uric acid eningi egazini lakho.

Kungathatha izinyanga ezimbalwa ngaphambi kokuba i-febuxostat iqale ukuvimbela ukuhlaselwa yi-gout. IFebuxostat ingakhuphula inani lokuhlaselwa yi-gout ezinyangeni ezimbalwa zokuqala zokwelashwa kwakho. Udokotela wakho angakunikeza omunye umuthi onjenge-colchicine (Colcyrs, Mitigare) noma umuthi wokulwa nokuvuvukala (i-NSAID) ukuvimbela ukuhlaselwa yi-gout ezinyangeni zokuqala eziyisithupha zokwelashwa kwakho. Qhubeka uthathe i-febuxostat noma ngabe uhlaselwa yi-gout ngesikhathi uselashwa kuqala.

IFebuxostat ilawula i-gout kepha ayiyelaphi. Qhubeka uthathe i-febuxostat noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-febuxostat ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-febuxostat,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-febuxostat, allopurinol, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-febuxostat. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-azathioprine (Azasan, Imuran) noma i-mercaptopurine (Purinethol, Purixan). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-febuxostat uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho i-theophylline (i-Elixophyllin, i-Theo-24, abanye) noma imithi yokwelashwa ngamakhemikhali yomdlavuza. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ngabe uke wafakelwa isitho somzimba; umdlavuza; I-Lesch-Nyhan syndrome (isifo esizuzwe njengefa esidala amazinga aphezulu e-uric acid egazini, ubuhlungu bamalunga, nezinkinga ngokunyakaza nokuziphatha); noma isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-febuxostat, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Febuxostat ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:

• isicanucanu
• ubuhlungu obuhlangene

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuqubuka; ukubomvu kwesikhumba noma ubuhlungu; ukushwabana kwezindebe, amehlo noma umlomo; ukukhishwa kwesikhumba; noma umkhuhlane nezinye izimpawu ezifana nomkhuhlane
• ukuvuvukala ubuso, izindebe, umlomo, ulimi noma umphimbo
• amehlo aphuzi noma isikhumba; umchamo omnyama; noma ubuhlungu noma ukungaphatheki kahle endaweni engaphezulu yesisu

I-Febuxostat ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa, kude nokukhanya, futhi kude nokushisa okwedlulele nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-febuxostat.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Uloric^®