Injection ye-Ofatumumab

-Delile

• Ngaphambi kokuthola umjovo we -atumumab,
• Umjovo we-Ofatumumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Kungenzeka ukuthi usungenwe yi-hepatitis B (igciwane elithelela isibindi futhi lingadala ukulimala kwesibindi) kepha ungabi nazimpawu zesifo. Kulokhu, umjovo we-ofatumumab ungakhuphula ubungozi bokuthi ukutheleleka kwakho kuzoba kubi kakhulu noma kusongele impilo futhi uzoba nezimpawu. Tshela udokotela wakho uma ngabe uke waba nokutheleleka ngegciwane le-hepatitis B. Udokotela wakho uzoku-oda ukuhlolwa kwegazi ukuze abone ukuthi une-virus engasebenzi ye-hepatitis B engasebenzi. Uma kunesidingo, udokotela wakho angakunika imithi yokwelapha lesi sifo ngaphambi nangesikhathi sokwelashwa kwakho nge-ofatumumab. Udokotela wakho uzokuhlola futhi nangezimpawu zokutheleleka kwesifo sokusha kwesibindi kohlobo B ngesikhathi nangezinyanga ezimbalwa ngemuva kokwelashwa kwakho. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhathala ngokweqile, ukuphuzi kwesikhumba noma kwamehlo, ukulahlekelwa isifiso sokudla, isicanucanu noma ukuhlanza, ubuhlungu bemisipha, ubuhlungu besisu, noma umchamo omnyama.

Abanye abantu abathola i-ofatumumab bahlakulele i-leukoencephalopathy eqhubekayo (i-PML); ukutheleleka okungavamile kobuchopho okungenakulashwa, ukuvinjelwa, noma ukwelashwa okuvame ukudala ukufa noma ukukhubazeka okukhulu) ngesikhathi noma ngemuva kokwelapha kwabo. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: izinguquko ezintsha noma ezingazelelwe ekucabangeni noma ekudidekeni, isiyezi, ukulahlekelwa ibhalansi, ubunzima bokukhuluma noma ukuhamba, ushintsho olusha noma oluzumayo embonweni, noma ezinye izimpawu ezingavamile ezithi gwa gqa.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-ofatumumab.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we -atumumab.

Umjovo we-Ofatumumab usetshenziselwa ukwelapha i-lymphocytic leukemia (CLL; uhlobo lomdlavuza wamaseli amhlophe egazi) kubantu abadala abangakatholi ngcono ngemuva kokwelashwa nge-fludarabine (Fludara) ne-alemtuzumab (Campath). Umjovo we-Ofatumumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokubulala amangqamuzana omdlavuza.

Umjovo we-Ofatumumab uza njengesisombululo (uketshezi) okufanele sengezwe kuketshezi futhi sijojowe ngomjovo (emthanjeni) ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma esibhedlela. Kuvamise ukujova kanye ngesonto amasonto ayi-8 bese kanye ngenyanga izinyanga ezi-4.

Udokotela wakho angadinga ukuphazamisa ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Udokotela wakho uzokunika eminye imishanguzo yokuvikela noma yokwelapha imiphumela ethile engemihle imizuzu engu-30 kuya emahoreni amabili ngaphambi kokuba uthole umjovo ngamunye womjovo we-ofatumumab. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa ngomjovo we-ofatumumab.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we -atumumab,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleathumab, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-ofatumumab. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nesifo esingapheliyo sokuphazamiseka kwamaphaphu (COPD; iqembu lezifo ezithinta amaphaphu nemigwaqo yomoya) noma i-hepatitis B (igciwane elithelela isibindi futhi elingadala ukulimala kwesibindi noma umdlavuza wesibindi).
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we -atumumab, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we -atumumab.
• buza udokotela wakho ukuthi kufanele yini ugonywe ngaphambi kokuba uqale ukwelashwa nge-ofatumumab. Ungabi nayo imigomo ngesikhathi sokwelashwa kwakho ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Ofatumumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuphazamiseka kwemisipha
• ikhala eligcwele noma eligijimayo
• isifo sohudo
• ikhanda
• ubunzima bokulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuphefumula kanzima noma ukugwinya
• ukujuluka okusindayo
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ukubomvu ngokungazelelwe kobuso, intamo, noma isifuba esingenhla
• ubuthakathaka
• ukopha okungajwayelekile noma ukulinyazwa
• isikhumba esiphaphathekile
• ukukhomba, okuyisicaba, okuyindilinga, amabala abomvu ngaphansi kwesikhumba
• ukuqubuka
• isifuba
• umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• ubuhlungu ezingalweni, emhlane, entanyeni, noma emhlathini
• ubuhlungu besifuba,
• ukushaya kwenhliziyo okusheshayo
• ukuquleka

Umjovo we-Ofatumumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we -atumatum.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Arzerra^®