Elvitegravir, Cobicistat, Emtricitabine, kanye neTenofovir

-Delile

• Ngaphambi kokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir,
• I-Elvitegravir, cobicistat, emtricitabine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO NOMA IZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo

I-Elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir akumele isetshenziselwe ukwelapha ukutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo). Tshela udokotela wakho uma unayo noma ucabanga ukuthi ungaba ne-HBV. Udokotela wakho angakuhlola ukuthi unayo yini i-HBV ngaphambi kokuba uqale ukwelashwa kwakho nge-elvitegravir, cobicistat, emtricitabine, ne-tenofovir. Uma une-HBV futhi uthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir, isimo sakho singase sibe sibi ngokuzumayo lapho uyeka ukuthatha lo muthi. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zebhu njalo ezinyangeni ezimbalwa ngemuva kokuyeka ukuthatha lo muthi ukubona ukuthi i-HBV yakho isiba kubi kakhulu.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-elvitegravir, cobicistat, emtricitabine, ne-tenofovir.

Khuluma nodokotela wakho ngezingozi zokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir.

Inhlanganisela ye-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir (i-Genvoya, i-Stribilid) isetshenziselwa ukwelapha ukutheleleka kwegciwane lesandulela-ngculazi (i-HIV) kubantu abadala nasezinganeni ezingazange zelashwe ngeminye imishanguzo ye-HIV noma ukubuyisela ukwelashwa kwamanje kubantu abathile uthatha imishanguzo ye-HIV. Inhlanganisela ye-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir ikusigaba semithi esibizwa ngama-antivirals. I-Elvitegravir, i-emtricitabine, ne-tenofovir isebenza ngokunciphisa inani le-HIV egazini. ICobicistat isiza ukugcina i-elvitegravir emzimbeni isikhathi eside ukuze umuthi ube nomthelela omkhulu. Yize ukuhlanganiswa kwe-elvitegravir, i-cobicistat, i-emtricitabine ne-tenofovir kungeke kuyelaphe i-HIV, le mithi inganciphisa ithuba lakho lokuthola i-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengokutheleleka okunzima noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko kwimpilo yakho kunganciphisa ingozi yokudlulisela igciwane lesandulela ngculaza kwabanye abantu.

Inhlanganisela ye-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir iza njengethebhulethi ezothathwa ngomlomo. Kuvame ukuthathwa nokudla kanye ngosuku. Thatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

I-Elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir iyasiza ekulawuleni ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka nokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-elvitegravir, cobicistat, emtricitabine, noma i-tenofovir, noma imuphi omunye umuthi, noma iziphi izithako ku-elvitegravir, cobicistat, emtricitabine, kanye namaphilisi e-tenofovir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• utshele udokotela wakho uma uthatha noma iyiphi yale mithi elandelayo: i-alfuzosin (i-Uroxatral); i-carbamazepine (Carbatrol, Epitol, Tegretol, abanye), i-cisapride (Propulsid) (ayitholakali e-U.S.); imithi ye-ergot efana ne-dihydroergotamine (i-DHE 45, i-Migranal), i-ergotamine (i-Ergomar, eCafergot, eMigergot), ne-methylergonovine (Methergine); lomitapide (Juxtapid); i-lovastatin (Altoprev); i-lurasidone (Latuda); i-midazolam (ihunyushiwe) ngomlomo; i-phenobarbital; i-phenytoin (iDilantin, Phenytek); ipimozide (i-Orap); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); ISt John's wort; i-sildenafil (i-Revatio kuphela, uphawu olusetshenziselwa isifo samaphaphu); simvastatin (Simcor, Zocor, eVytorin); noma i-triazolam (Halcion). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir uma uthatha owodwa noma ngaphezulu wale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antibiotic e-aminoglycoside afana ne-gentamicin; ama-anticoagulants (’blood thinner’) afana ne-apixaban (Eliquis), amandlaxaban (Bevyxxa), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban powder (Xarelto), ne-warfarin (Coumadin, Jantoven); imishanguzo yokulwa ne-fungal efana ne-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole, ne-voriconazole (i-Vfend); imishanguzo efana ne-acyclovir (Sitavig, Zovirax), i-cidofovir, i-ganciclovir (i-cytovene), i-valacyclovir (i-Valtrex), ne-valganciclovir (i-Valcyte); i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-atorvastatin (Lipitor, eCaduet); i-benzodiazepines efana ne-clonazepam (i-Klonopin), i-clorazepate (i-Gen-Xene, i-Tranxene), i-diazepam (i-Diastat, i-Valium), i-estazolam, i-flurazepam, ne-midazolam inikezwe ngemithambo (emthanjeni); ama-beta blocker anjenge-metoprolol (Lopressor, Toprol-XL, eDutoprol) kanye ne-timolol; i-bosentan (iTracleer); i-buprenorphine ne-naloxone (i-Bunavail, i-Suboxone); buspirone; ama-calcium channel blocker anjenge-amlodipine (Norvasc), diltiazem (Cardizem, Diltzac, Tiazac, others), felodipine, nicardipine (Cardene), nifedipine (Adalat CC, Afeditab CR, Procardia), kanye ne-verapamil (Calan, Verelan, eTarka); i-clarithromycin (i-Biaxin, ku-PrevPac); i-colchicine (Colcrys, Mitagare, kuCol-Probenecid); i-dexamethasone; i-ethosuximide (iZarontin), izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, isichibi, iringi yesitho sangasese sowesifazane, noma ukujova); imishanguzo yokudangala njenge-amitriptyline, bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Brisdelle, Paxil, Pexeva), ne-trazodone; eminye imithi ye-HIV noma i-AIDS kubandakanya i-cobicistat (iTybost, e-Evotaz, e-Prezcobix), i-emtricitabine (i-Emtriva, e-Atripla, e-Complera, eTruvada), lamivudine (i-Epivir, e-Combivir, e-Epzicom, e-Trizivir, abanye), ritonavir ENorvir, eKaletra, eTevivie), nase-tenofovir (eViread, e-Atripla, eComplera, eTruvada); i-fentanyl (i-Actiq, i-Duragesic, i-Subsys); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), disopyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), ne-quinidine (eNuedexta); imithi evimbela amasosha omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ne-tacrolimus (Prograf); naloxone (Evzio, Narcan); oxcarbazepine (Oxtellar XR, Trileptal); i-perphenazine; i-quetiapine (iSeroquel); i-phosphodiesterase (PDE5) inhibitors njenge-sildenafil (Viagra), i-tadalafil (i-Adcirca, i-Cialis), ne-vardenafil (i-Levitra, i-Staxyn); i-rifabutin (i-Mycobutin); i-rifapentine (Priftin); i-risperidone (i-Risperdal); i-salmeterol (iSerevent, e-Advair); i-steroids yomlomo noma ehogelwayo efana ne-betamethasone, i-budesonide (i-Pulmicort), i-ciclesonide (i-Alvesco, i-Omnaris), i-dexamethasone, i-fluticasone (i-Flonase, i-Flovent, e-Advair), i-methylprednisolone (i-Medrol). i-mometasone (eDulera). i-prednisone (iRayos), ne-triamcinolone; i-telithromycin (Ketek; ayisatholakali e-US); thioridazine; i-tramadol; kanye ne-zolpidem (Ambien, Edluar, Intermezzo, Zolpimist). Eminye imithi eminingi ingaxhumana ne-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• uma uthatha ama-antacids aqukethe i-aluminium, i-magnesium, noma i-calcium (Maalox, Mylanta, abanye), thatha amahora amabili ngaphambi noma amahora amabili ngemuva kwe-elvitegravir, cobicistat, emtricitabine, ne-tenofovir.
• Tshela udokotela wakho uma ngabe uke waba nezimo okukhulunywe ngazo esigabeni ESIBALULEKILE SESEXWAYISO, izinkinga zamathambo kufaka phakathi i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi aphuke kalula) noma ukuphuka kwamathambo, noma yiluphi uhlobo lwesifo olungahambi kude noma okuzayo nokudlulayo njengesifo sofuba (i-TB; uhlobo lokutheleleka kwamaphaphu) noma i-cytomegalovirus (i-CMV; ukutheleleka ngegciwane okungadala izimpawu ezigulini ezinamasosha omzimba abuthakathaka), noma isifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir, shayela udokotela wakho khona manjalo. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthatha i-elvitegravir, cobicistat, emtricitabine ne-tenofovir.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi phakathi nokwelashwa kwakho nge-elvitegravir, cobicistat, emtricitabine, ne-tenofovir, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula ngokudla. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Elvitegravir, cobicistat, emtricitabine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ubunzima bokulala noma ukulala
• amaphupho angajwayelekile
• isifo sohudo
• igesi
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO NOMA IZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo

• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ubunzima bokugwinya noma ukuphefumula
• ukuncipha kokuchama
• ubuhlungu ezingalweni, ezandleni, ezinyaweni, noma emilenzeni
• ubuhlungu engxenyeni engakwesokudla esiswini sakho
• ukulahlekelwa isifiso sokudla
• izimpawu ezinjengomkhuhlane
• isicanucanu
• ukuhlanza
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ubuthakathaka
• isiyezi
• ubumhlophe
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ukuphefumula kanzima
• umchamo omnyama ophuzi noma onsundu
• ukunyakaza kwamathumbu okukhanyayo
• ukuphuzi kwesikhumba noma kwamehlo
• ukuzwa ukubanda, ikakhulukazi ezandleni noma emilenzeni
• ubuhlungu bemisipha

I-Elvitegravir, cobicistat, emtricitabine, ne-tenofovir kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina i-elvitegravir, i-cobicistat, i-emtricitabine, ne-tenofovir esandleni. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UGenvoya^® (equkethe iCobicistat, Elvitegravir, Emtricitabine, Tenofovir)
• Stribild^® (equkethe iCobicistat, Elvitegravir, Emtricitabine, Tenofovir)