Inaliti ye-Dulaglutide

-Delile

• Ngaphambi kokusebenzisa i-dulaglutide,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• I-Dulaglutide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukusebenzisa i-dulaglutide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Dulaglutide ungakhuphula ubungozi bokuthi uzoba nezicubu zomgudu wegilo, kufaka phakathi i-medullary thyroid carcinoma (MTC; uhlobo lomdlavuza wegilo). Izilwane zaselabhorethri ezinikezwe i-dulaglutide zaba nezimila, kepha akwaziwa ukuthi lo muthi wandisa ingozi yezimila kubantu. Tshela udokotela wakho ukuthi ngabe wena noma omunye umuntu emndenini wakho une-MTC noma i-Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; isimo esidala izicubu ngaphezulu kwendlala eyodwa emzimbeni). Uma kunjalo, udokotela wakho uzokutshela ukuthi ungasebenzisi umjovo we-dulaglutide. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isigaxa noma ukuvuvukala entanyeni; ukushaqeka; ubunzima bokugwinya; noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ukuhlola impendulo yomzimba wakho kumjovo we-dulaglutide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-dulaglutide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-dulaglutide.

Umjovo we-Dulaglutide usetshenziselwa uhlelo lokudla nokuzivocavoca ukulawula amazinga kashukela egazini kubantu abadala abanesifo sikashukela sohlobo 2 (isimo lapho umzimba ungasebenzisi i-insulin ngokujwayelekile ngakho-ke awukwazi ukulawula inani likashukela egazini). Umjovo we-Dulaglutide nawo usetshenziselwa ukunciphisa ubungozi bokuhlaselwa yinhliziyo, ukushaywa unhlangothi, noma ukufa kubantu abadala abane-type 2 diabetes mellitus abanesifo senhliziyo noma abasengozini yokuhlaselwa yisifo senhliziyo. Umjovo we-Dulaglutide awusetshenziswanga ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi khona i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma isifo sikashukela ketoacidosis (isimo esibi esingakhula uma ushukela wegazi ongelashwa) . Umjovo we-Dulaglutide usesigabeni semithi ebizwa nge-incretin mimetics. Isebenza ngokusiza ama-pancreas ukukhipha inani elifanele le-insulin lapho amazinga kashukela egazi ephezulu. I-insulin isiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. Umjovo we-Dulaglutide nawo usebenza ngokunciphisa ukuhamba kokudla esiswini.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

Umjovo we-Dulaglutide uza njengesisombululo (uketshezi) epeni lokufaka elifakiwe ukuze ujove ngaphansi (ngaphansi kwesikhumba) esiswini sakho, ethangeni, noma engalweni ephezulu. Imvamisa ijovwa kanye ngesonto ngaphandle kokubheka ukudla. Sebenzisa umjovo we-dulaglutide ngosuku olufanayo evikini ngalinye nganoma yisiphi isikhathi sosuku. Ungashintsha usuku lweviki olisebenzisa i-dulaglutide inqobo nje uma sekunezinsuku ezi-3 noma ngaphezulu selokhu wasebenzisa umthamo wakho wokugcina. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-dulaglutide njengoba nje uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Umjovo we-Dulaglutide ulawula isifo sikashukela kepha awuselaphi. Qhubeka nokusebenzisa umjovo we-dulaglutide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-dulaglutide ngaphandle kokukhuluma nodokotela wakho.

I-Dulaglutide ingena ezibayeni ezithandayo zokufaka ezinemithi eyenele yedosi eyodwa. Faka njalo i-dulaglutide ngepeni laso elithandayo; ungalinge uyixube nomunye umuthi.

Funda ngokucophelela imiyalelo yomkhiqizi yokusetshenziswa eza nomuthi. Le miyalo ichaza ukuthi ungalungiselela kanjani futhi ujove umthamo womjovo we-dulaglutide. Qiniseka ukuthi ubuza usokhemisi noma udokotela wakho uma unemibuzo mayelana nokuthi ungawujova kanjani lo muthi.

Njalo bheka isisombululo se-dulaglutide ngaphambi kokusijova. Kufanele icace, ingenambala, futhi ingenazo izinhlayiya eziqinile.

Ungafaka i-dulaglutide engalweni yakho ephezulu, ethangeni, noma esiswini. Ungalokothi ufake i-dulaglutide emthanjeni noma emisipheni. Shintsha (jikelezisa) indawo yokujova ngaphakathi kwendawo ekhethiwe ngomthamo ngamunye. Ungajova i-dulaglutide ne-insulin endaweni efanayo yomzimba, kepha akufanele unikeze imijovo eduze komunye nomunye.

Ungalokothi uphinde usebenzise noma wabelane ngamapeni wokulinganisa. Lahla izibaya esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-dulaglutide,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-dulaglutide, noma imuphi omunye umuthi, noma yiziphi izithako zomjovo we-dulaglutide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyiphuzayo ngomlomo ngoba i-dulaglutide ingashintsha indlela umzimba wakho oyithatha ngayo le mithi. Futhi qiniseka ukuthi ukhuluma ngemithi ye-insulin noma yomlomo yesifo sikashukela ikakhulukazi i-sulfonylureas, kufaka phakathi i-chlorpropamide (i-Diabinese), i-glimepiride (i-Amaryl, e-Avandaryl, e-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, e-Glucovance), i-tolazamide, ne-tolbutamide. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma uke waba ne-pancreatitis noma (wake wavuvukala amanyikwe); i-retinopathy yesifo sikashukela (ukulimala kwamehlo okubangelwa yisifo sikashukela); izinkinga ezinzima zesisu, kufaka phakathi i-gastroparesis (ukuhamba kancane kokudla kusuka esiswini kuya emathunjini amancane) noma ezinye izinkinga zokugaya ukudla; noma isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-dulaglutide, shayela udokotela wakho.
• buza udokotela wakho ukuthi yini okufanele uyenze uma ugula, uba nesifo noma umkhuhlane, uba nengcindezi engajwayelekile, noma ulimele. Lezi zimo zingathinta ushukela wakho wegazi kanye nenani le-dulaglutide ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula bese uqhubeka nesimiso sakho esijwayelekile samasonto onke. Kodwa-ke, uma kunezinsuku ezingaphansi kwezingu-3 kuze kufike umthamo wakho olandelayo ohleliwe, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa okujwayelekile. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-Dulaglutide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• isicanucanu
• isilungulela
• ukuncipha kokudla
• ngizizwe ngikhathele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukusebenzisa i-dulaglutide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obuqhubekayo obuqala ngaphezulu kwesobunxele noma maphakathi nesisu kepha bungadlulela emuva
• ukuhlanza
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kwezindebe, ulimi, ubuso, noma umphimbo
• umbono uyashintsha
• ukushaya kwenhliziyo okusheshayo

I-Dulaglutide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina lo muthi kwikhathoni yoqobo esiqandisini, uvikelekile ekukhanyeni. Ungafrizi. Uma kunesidingo, ipeni ngalinye lomthamo eligcwalisiwe lingagcinwa ekamelweni lokushisa kuze kube yizinsuku eziyi-14. Gcina i-dulaglutide lapho izingane zingafinyeleli khona.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• izimpawu ze-hypoglycemia

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Trulicity^®