Naloxegol

-Delile

• Ngaphambi kokuthatha i-naloxegol,
• INaloxegol ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalesi sibonakaliso, yeka ukuthatha i-naloxegol bese ushayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

INaloxegol isetshenziselwa ukwelapha ukuqunjelwa okubangelwa yimithi yezinhlungu i-opiate (narcotic) kubantu abadala abanezinhlungu ezingapheli (eziqhubekayo) ezingabangelwa umdlavuza. UNaloxegol usekilasini lemithi ebizwa ngokuthi yi-peripherally acting mu-opioid receptor antagonists. Isebenza ngokuvikela amathumbu emiphumeleni yemithi ye-opiate (narcotic).

INaloxegol iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku, okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla kokuqala kosuku. Thatha i-naloxegol ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-naloxegol njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma ungakwazi ukuwagwinya wonke amaphilisi, yichoboze ithebhulethi ibe yimpuphu bese uyixuba engilazini enama-ounces ayi-120 wamanzi. Phuza ingxube ngokushesha. Bese ugcwalisa ingilazi ngama-ounces ama-4 (120 ml) wamanzi, ugovuze okuqukethwe, uphuze okusele kwengxube.

Uma uneshubhu le-nasogastric (NG), udokotela wakho noma usokhemisi uzokuchazela ukuthi ungawalungisa kanjani amaphilisi e-naloxegol ukuze unikeze ngepayipi le-NG.

Kufanele uyeke ukuthatha eminye imithi ye-laxative ngaphambi kokuthi uqale ukuthatha i-naloxegol. Qiniseka ukuthi wazisa udokotela wakho uma i-naloxegol ingakusebenzeli ngemuva kokuyithatha izinsuku ezintathu. Udokotela wakho angakutshela ukuthi uthathe eminye imithi yokwelapha i-laxative.

Tshela udokotela wakho uma uyeka ukuthatha imishanguzo ye-opiate (narcotic). Udokotela wakho mhlawumbe uzokutshela ukuthi uyeke ukuthatha i-naloxegol.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-naloxegol,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-naloxegol, noma imiphi eminye imithi, noma yiziphi izithako ezikumaphilisi e-naloxegol. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-clarithromycin (Biaxin), itraconazole (Onmel, Sporanox), noma ketoconazole (Nizoral). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-naloxegol uma uphuza eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Tegretol); i-diltiazem (iCardizem, iDilacor, iTiazac); i-efavirenz (e-Atripla, eSustiva); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-methadone (i-Dolophine, i-Methadose); abanye abaphikisana nama-opiate njenge-methylnaltrexone (Relistor), naloxone (Evzio, eBunavail, eSuboxone, eZubsolv), noma i-naltrexone (Revia, ku-Contrave, e-Embeda, eVivitrol); i-rifampin (iRifadin, eRifamate, iRifater, iRimactane); noma i-verapamil (Calan, Covera, Verelan). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-naloxegol, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSt John's Wort.
• Tshela udokotela wakho uma ngabe uke waba nokuvinjelwa kwamathumbu noma wake waba nokuvaleka emathunjini akho. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-naloxegol.
• Tshela udokotela wakho uma uke waba nezinkinga zesisu noma zamathumbu njengezilonda zesisu (izilonda esiswini sesisu), isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukwehla kwesisindo, nomkhuhlane), i-diverticulitis (ama-bulges avuvukele ngaphakathi kolwelwesi olukhulu), umdlavuza wesisu noma wamathumbu, noma i-Ogilvie's syndrome (isimo lapho kunesigaxa khona emathunjini); noma isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-naloxegol, shayela udokotela wakho.

Ungadli isithelo samagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

INaloxegol ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• isicanucanu
• igesi
• ubuhlungu besisu
• ukuhlanza
• ikhanda
• ukujuluka
• Ukugodola
• ukukhathazeka
• ukucasuka
• kuzamula

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalesi sibonakaliso, yeka ukuthatha i-naloxegol bese ushayela udokotela wakho ngokushesha:

• Ubuhlungu besisu obunzima noma obubi futhi nohudo
• ukuqubuka; isifuba; ukuvuvukala kobuso, izindebe, umphimbo, ulimi, izandla, noma izinyawo

INaloxegol ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ubuhlungu besisu
• isifo sohudo
• isicanucanu
• Ukugodola
• ikhala eligijimayo
• ukujuluka

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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