Umjovo wePaliperidone

-Delile

• Ngaphambi kokuthola umjovo okhululiwe we-paliperidone,
• Umjovo wePaliperidone ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka kobuchopho okuthinta ikhono lokukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha ama-antipsychotic (imithi yokugula kwengqondo) njenge-paliperidone babe nethuba elandayo lokufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo bangaba nethuba elikhulu lokuba nesifo sohlangothi noma i-ministroke ngesikhathi sokwelashwa.

Umjovo wePaliperidone enwetshiwe (osebenza isikhathi eside) awuvunyelwe yi-Food and Drug Administration (FDA) ekwelapheni ukuphazamiseka kokuziphatha kubantu abadala asebekhulile abanenkinga yokuwohloka komqondo. Khuluma nodokotela onqume lo muthi uma wena, ilungu lomndeni, noma umuntu omnakekelayo enesifo sengqondo sokuphazamiseka komqondo futhi elashwa ngomjovo wokukhipha oweluliwe we-paliperidone. Ngeminye imininingwane vakashela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo wokukhishwa okwandisiwe kwe-paliperidone.

Imijovo yokukhishwa kwe-Paliperidone enwetshiwe (i-Invega Sustenna, i-Invega Trinza) isetshenziselwa ukwelapha i-schizophrenia (ukugula kwengqondo okubangela ukucabanga okuphazamisayo noma okungajwayelekile, ukuphelelwa yintshisekelo empilweni, kanye nemizwa enamandla noma engafanele). Umjovo wokukhishwa kwe-Paliperidone enwetshiwe (i-Invega Sustenna) nawo usetshenziswa wedwa noma neminye imithi yokwelapha isifo se-schizoaffective (ukugula ngengqondo okubangela ukulahleka kokuxhumana nezinkinga zangempela nezemizwa [ukudangala noma i-mania]). Umjovo wokukhishwa okwandisiwe wePaliperidone usekilasini lemithi ebizwa nge-atypical antipsychotic. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

Imijovo ekhishwe isikhathi eside yePaliperidone iza njengokumiswa (uketshezi) ukuze kujovwe ngemisipha ngumhlinzeki wezokunakekelwa kwempilo. Ngemuva kokuthola umthamo wakho wokuqala we-paliperidone injection-release-injection (Invega^® Sustenna), uzothola umthamo wesibili imvamisa isonto elilodwa ngemuva komthamo wokuqala bese uphinde njalo ngenyanga. Uma usuthole okungenani izinyanga ezine zokwelashwa ngomjovo wokukhipha oweluliwe we-paliperidone (Invega Sustenna), udokotela wakho angakushintshela kumjovo wokukhishwa oweluliwe we-paliperidone (Invega Trinza). Umjovo wokukhishwa okwandisiwe wePaliperidone (Invega Trinza) uvamise ukujojwa emsipheni ngumhlinzeki wezokunakekelwa kwezempilo kanye ezinyangeni ezintathu.

Umjovo wokukhishwa okwandisiwe wePaliperidone ungasiza ukulawula izimpawu zakho kepha ngeke uselaphe isimo sakho. Qhubeka nokugcina ama-aphoyintimenti ukuthola umjovo wokukhishwa okwandisiwe kwe-paliperidone noma ngabe uzizwa uphilile. Khuluma nodokotela wakho uma ungazizwa sengathi uba ngcono ngesikhathi sokwelashwa kwakho ngomjovo wokukhishwa okwandisiwe we-paliperidone.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo okhululiwe we-paliperidone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-paliperidone, i-risperidone (i-Risperdal, i-Risperdal Consta), noma imuphi omunye umuthi, noma iziphi izithako zomjovo wokukhipha oweluliwe we-paliperidone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: eminye imishanguzo yokuthambisa imishanguzo efana ne-chlorpromazine, risperidone (Risperdal, Risperdal Consta), ne-thioridazine; imithi yengcindezi yegazi; i-carbamazepine; isisu (‘amaphilisi amanzi’); ama-dopamine agonists afana ne-bromocriptine (i-Cycloset, i-Parlodel), i-cabergoline, i-levodopa ne-carbidopa (i-Duopa, i-Rytary, i-Sinemet, abanye), i-pramipexole (i-Mirapex), i-ropinirole (i-Requip), ne-rotigotine (i-Neupro); ama-antibiotic e-fluoroquinolone njenge-gatifloxacin (i-Zymar, i-Zymaxid) ne-moxifloxacin (i-Avelox); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Cordarone, Nexterone, Pacerone), procainamide, quinidine (eNuedexta); i-rifampin; ne-sotalol (iBetapace, iSorine). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma unezinga eliphansi le-potassium noma i-magnesium egazini lakho, inani eliphansi lamaseli amhlophe egazi, noma uma kukhona omunye umuthi owake wadala ukwehla kwamaseli akho amhlophe egazi. Phinda utshele udokotela wakho uma uke wahlaselwa yisifo sohlangothi, isifo sohlangothi, i-ministroke, isifo senhliziyo, ukwehluleka kwenhliziyo, ukushaya kwenhliziyo okungajwayelekile, i-QT syndrome ende (isimo esandisa ubungozi bokushaya ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma kungazelelwe ukufa), ukunyakaza okungalawulwa kolimi lwakho, ubuso, umlomo, noma umhlathi, unenkinga yokugcina ibhalansi yakho, isifo sikaParkinson (PD; ukuphazamiseka kwesistimu yezinzwa okubangela ubunzima ngokunyakaza, ukulawula imisipha nokulinganisela), ukuwohloka komqondo komzimba kaLeyy (a isimo lapho ubuchopho buqala khona ukwakheka kwamaprotheni angajwayelekile, futhi ubuchopho nohlelo lwezinzwa lubhujiswa ngokuhamba kwesikhathi), ubunzima bokugwinya, i-dyslipidemia (amazinga aphezulu e-cholesterol), inhliziyo, isibindi, noma isifo sezinso, noma uma wena noma omunye emndenini wakho owake waba nesifo sikashukela. Tshela udokotela wakho uma uhlanza kakhulu, uhudo noma izimpawu zokuphelelwa amandla emzimbeni manje, noma uma uba nalezi zimpawu noma kunini ngesikhathi sokwelashwa kwakho.
• tshela udokotela wakho uma ukhulelwe, uma uhlela ukukhulelwa, noma uma uncelisa. Uma ukhulelwa ngesikhathi sokwelashwa kwakho ngomjovo wokukhipha oweluliwe we-paliperidone, shayela udokotela wakho.
• kufanele wazi ukuthi ukuthola umjovo okhululiwe we-paliperidone kungakwenza ukozele futhi kungathinta ikhono lakho lokucabanga kahle, wenze izinqumo futhi usabele ngokushesha. Ungashayeli imoto noma usebenzise imishini ngezinye izikhathi ngesikhathi sokwelashwa kwakho ngomjovo wokukhipha oweluliwe we-paliperidone uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi ungathola i-hyperglycemia (inyuka kushukela egazini lakho) ngenkathi uthola lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukuthola umjovo wokukhishwa okwandisiwe we-paliperidone noma imishanguzo efanayo kungandisa le ngozi. Tshela udokotela wakho ngokushesha uma unalezi zimpawu ezilandelayo ngesikhathi sokwelashwa kwakho: ukoma ngokweqile, ukuchama kaningi, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi umjovo okhululiwe we-paliperidone ungadala isizungu, ikhanda elikhanyayo, ukushaya kwenhliziyo okusheshayo noma okuhamba kancane, nokuquleka lapho uvuka ngokushesha okukhulu kusuka endaweni elele, ikakhulukazi ngemuva nje kokuthola umjovo wakho. Uma uzizwa unesiyezi noma ukozela ngemuva kokuthola umjovo wakho, kuzodingeka ulale phansi uze uzizwe ungcono. Ngesikhathi sokwelashwa kwakho, kufanele uvuke embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi umjovo wokukhishwa okwandisiwe kwe-paliperidone kungenza kube nzima emzimbeni wakho ukuphola lapho kushisa kakhulu. Tshela udokotela wakho uma uhlela ukuzivocavoca ngamandla noma uvezwe ukushisa okukhulu. Qiniseka ukuthi uphuza amanzi amaningi futhi ushayele udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo: uzizwa ushisa kakhulu, ujuluka kakhulu, ungajuluki yize kushisa, umlomo womile, ukoma ngokweqile noma ukwehla kokuchama.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo wePaliperidone ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu, ukuvuvukala, ububomvu endaweni yomjovo
• ukukhathala ngokweqile
• isiyezi, ukuzizwa ungagxilile, noma unenkinga yokugcina ibhalansi yakho
• ukungahlaliseki
• ukuyaluza
• ikhanda
• umlomo owomile
• ukuzuza kwesisindo
• ubuhlungu besisu noma ukungaphatheki kahle
• ukukhishwa kwebele
• uphuthelwe ukuya esikhathini
• ukukhuliswa kwebele kwabesilisa
• kwehle ikhono lezocansi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• ukulunywa
• isifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala, kanye / noma imilenze engezansi
• ubunzima bokugwinya noma ukuphefumula
• ukudlikiza
• imfiva
• ukuqina kwemisipha
• ukuwa
• ukushaya kwenhliziyo okungajwayelekile
• ukudideka
• ukulahlekelwa ukwazi
• ukunyakaza okungajwayelekile noma okungalawulwa komlomo, ulimi, ubuso, ikhanda, intamo, izingalo nemilenze
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ukunyakaza okuhamba kancane noma ukushova ukuhamba
• ukwakhiwa okubuhlungu kwenduku okuhlala amahora
• ukukhwehlela, ukubanda kanye / noma ezinye izimpawu zokutheleleka

Umjovo wePaliperidone ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukozela
• ukukhathala ngokweqile
• ukushaya kwenhliziyo okwenyukile noma okungajwayelekile
• isithuthwane
• ukunyakaza okuhamba kancane noma ukushova ukuhamba
• ukunyakaza okungajwayelekile noma okungalawulwa komlomo, ulimi, ubuso, ikhanda, intamo, izingalo nemilenze

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo wokukhishwa okwandisiwe kwe-paliperidone.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Invega Sustenna^®
• Invega Trinza^®