Inaliti ye-Defibrotide

-Delile

• Ngaphambi kokuthola umjovo we-defibrotide,
• Umjovo we-Defibrotide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Defibrotide usetshenziselwa ukwelapha abantu abadala nezingane ezine-hepatic veno-occlusive disease (i-VOD; imithambo yegazi evinjiwe ngaphakathi kwesibindi, eyaziwa nangokuthi yi-sinusoidal obstruction syndrome), enezinkinga zezinso noma zamaphaphu ngemuva kokuthola ukufakelwa kwe-stem-cell ye-hematopoietic (HSCT; inqubo lapho kukhishwa khona amaseli athile egazi emzimbeni bese ebuyiselwa emzimbeni). Umjovo we-Defibrotide usesigabeni semithi ebizwa ngama-antithrombotic agents. Isebenza ngokuvimbela ukwakheka kwamahlule egazi.

Umjovo we-Defibrotide uza njengesisombululo (uketshezi) sokujova ngomjovo (emthanjeni) ngaphezu kwamahora ama-2 ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa ijovwa kanye njalo emahoreni ayisithupha izinsuku ezingama-21, kepha inganikezwa kuze kube yizinsuku ezingama-60. Ubude bokwelashwa buxhomeke ekutheni umzimba wakho uphendula kanjani emithini kanye nemiphumela emibi ongayithola.

Udokotela wakho kungadingeka ukuthi akubambezele noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-defibrotide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-defibrotide,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-defibrotide, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-defibrotide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha noma uthole ama-anticoagulants ('blood thinner') njenge-apixaban (Eliquis), dabigatran (Pradaxa), dalteparin (Fragmin), edoxaban (Savaysa), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin , i-rivaroxaban powder (i-Xarelto), ne-warfarin (i-Coumadin, i-Jantoven) noma uma uzobe uthola imishanguzo yokwenziwa kwe-thrombolytic drug tissue plasminogen activators efana ne-alteplase (Activase), reteplase (Retavase), noma i-tenecteplase (TNKase). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi umjovo we-defibrotide uma uthatha noma usebenzisa eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uphuma noma kuphi emzimbeni wakho noma uma unezinkinga zokopha.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola, shayela udokotela wakho. Ungancelisi ibele ngenkathi uthola umjovo we-defibrotide.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Defibrotide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi
• isifo sohudo
• ukuhlanza
• isicanucanu
• ukuphuma kwamakhala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kobuso, izindebe, ulimi noma umphimbo
• ukopha okungajwayelekile noma ukulinyazwa
• igazi emchameni noma esitulweni
• ikhanda
• ukudideka
• inkulumo engahambi kahle
• umbono uyashintsha
• umkhuhlane, ukukhwehlela, noma ezinye izimpawu zokutheleleka

Umjovo we-Defibrotide ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-defibrotide.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo we-defibrotide.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Defitelio^®