Inaliti ye-Olaratumab

-Delile

• Ngaphambi kokuthatha umjovo we-olaratumab,
• Umjovo we-Olaratumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

Ocwaningweni lomtholampilo, abantu abathole umjovo we-olaratumab ngokuhlangana ne-doxorubicin abaphili isikhathi eside kunalabo abathole ukwelashwa nge-doxorubicin kuphela. Njengomphumela wolwazi olutholwe kulolu cwaningo, umenzi uthatha umjovo we-olaratumab emakethe. Uma usuvele uthola ukwelashwa ngomjovo we-olaratumab kubalulekile ukuthi ubuze udokotela wakho ukuthi kufanele uqhubeke nokwelashwa yini. Le mithi isazotholakala ngqo kumenzi wayo kubantu asebeqalile ukwelashwa nge-olaratumab, uma odokotela babo bencoma ukwelashwa okuqhubekayo.

Umjovo we-Olaratumab usetshenziswa kanye nomunye umuthi ukwelapha izinhlobo ezithile ze-sarcoma ethambile yezicubu (umdlavuza oqala ezicutshini ezithambile njengemisipha, amafutha, imisipha, imizwa, nemithambo yegazi), engenakulashwa ngempumelelo ngokuhlinzwa noma ngemisebe. Umjovo we-Olaratumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokunciphisa noma ngokumisa ukukhula kwamangqamuzana omdlavuza.

Umjovo we-Olaratumab uza njengesisombululo (uketshezi) ukujova kancane emthanjeni ngaphezu kwemizuzu engama-60 ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa ijovwa ngezinsuku 1 no-8 zomjikelezo wezinsuku ezingama-21. Umjikelezo ungaphindwa njengoba kunconywe udokotela wakho. Ubude bokwelashwa kwakho buncike ekutheni umzimba wakho uphendula kahle kanjani emithini nasemiphumeleni oyitholayo.

Umjovo we-Olaratumab ungadala ukusabela okukhulu ngesikhathi sokufakwa komuthi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: ukuqhuma, umkhuhlane, amakhaza, isiyezi, ukuzizwa uphela amandla, ukuphefumula, ukuqhuma noma isifuba, ukuphefumula kanzima, noma ukuvuvukala kobuso noma umphimbo. Udokotela noma umhlengikazi uzokubheka ngokucophelela ngale miphumela engemihle ngenkathi umuthi ufakwa, futhi ngemuva kwesikhashana. Udokotela wakho kungadingeka ukuthi anciphise ukumnika kwakho, anciphise umthamo wakho, noma abambezele noma ayeke ukwelashwa kwakho uma uhlangabezana nalezi noma eminye imiphumela emibi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha umjovo we-olaratumab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-olaratumab, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-olaratumab. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele ukhulelwe ngesikhathi sokwelashwa kwakho ngomjovo we-olaratumab nezinyanga ezi-3 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthatha umjovo we-olaratumab, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Udokotela wakho angakutshela ukuthi ungancelisi ngesikhathi sokwelashwa kwakho ngomjovo we-olarartumab nezinyanga ezintathu ngemuva komthamo wakho wokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Olaratumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• izilonda noma ukuvuvukala emlonyeni noma emphinjeni
• ukulahleka kwezinwele
• ikhanda
• ukuzizwa ngikhathazekile
• amehlo omile
• ubuhlungu bemisipha, obuhlangene, noma bethambo kunoma iyiphi ingxenye yomzimba
• isikhumba esiphaphathekile
• ukukhathala okungavamile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• ukuvutha, ukushoshozela, ukuba ndikindiki, ubuhlungu, noma ubuthakathaka ezingalweni noma emilenzeni

Umjovo we-Olaratumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-olaratumab.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo we-olaratumab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Lartruvo^®