I-Letermovir

-Delile

• Ngaphambi kokuthatha i-letermovir,
• ILetermovir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

I-Letermovir isetshenziselwa ukusiza ukuvimbela ukutheleleka kwe-cytomegalovirus (CMV) kanye nezifo kubantu abathile abathole ukufakelwa kweseli-hematopoietic stem-cell (HSCT; inqubo ethatha indawo yomnkantsha onezifo ngomnkantsha onempilo) futhi basengozini enkulu yokutheleleka nge-CMV . ILetermovir isekilasini lemithi ebizwa ngama-antivirals. Isebenza ngokubambezela ukukhula kwe-CMV.

I-Letermovir iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye ngosuku. Udokotela wakho mhlawumbe uzokutshela ukuthi uqale ukuthatha i-letermovir ngemuva kokuthola ukufakelwa futhi uyeke ukuthatha umuthi ezinsukwini eziyi-100 ngemuva kokufakelwa. Thatha i-letermovir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-letermovir njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-letermovir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-letermovir, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-letermovir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha ama-ergot alkaloids afana ne-ergotamine (Ergomar, eCafergot, Migergot), kanye ne-dihydroergotamine (iDHE 45, Migranal), ne-pimozide (Orap). Udokotela wakho mhlawumbe uzokutshela ukuthi ungayithathi le mithi uma uthatha i-letermovir. Phinda utshele udokotela wakho uma uthatha i-cyclosporine kanye ne-simvastatin noma i-pitavastatin. Udokotela wakho mhlawumbe uzokutshela ukuthi ungayithathi le nhlanganisela yemithi ngeletermovir.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Nexterone, Pacerone); i-cyclosporine (Gengraf, Neoral, Sandimmune); fentanyl (Actiq, Duragesic, Subsys, abanye); i-glyburide (i-Diabeta, i-Glynase); I-HMG-CoA reductase inhibitors efana ne-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), ne-simvastatin (Flolipid, I-Vytorin); i-omeprazole (Prilosec, eYosprala, eZegerid); i-pantoprazole (Protonix); i-phenytoin (iDilantin, Phenytek); i-sirolimus (i-Rapamune); i-quinidine (ku-Nuedexta); i-repaglinide (Prandin); i-rifampin (Rifadin, Rimactane, eRfater, Rifamate), rosiglitazone (Avandia); tacrolimus (Astagraf, Envarsus, Prograf); i-voriconazole (Vfend); kanye ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana neletermovir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-letermovir, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-letermovir.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ILetermovir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukuvuvukala kwezingalo noma imilenze yakho
• ikhanda
• ukukhathala ngokweqile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile; ukuzizwa ubuthakathaka noma unesiyezi, ukuphefumula kanzima, ubuhlungu besifuba

ILetermovir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-letermovir.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Prevymis^®