IDoravirine, iLamivudine, neTenofovir

-Delile

• Ngaphambi kokuthatha i-doravirine, i-lamivudine, ne-tenofovir,
• IDoravirine, lamivudine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Inhlanganisela ye-doravirine, i-lamivudine, ne-tenofovir akufanele isetshenziselwe ukwelapha ukutheleleka ngegciwane le-hepatitis B (i-HBV; ukutheleleka kwesibindi okuqhubekayo). Tshela udokotela wakho uma unayo noma ucabanga ukuthi ungaba ne-HBV. Udokotela wakho angakuhlola ukuthi unayo yini i-HBV ngaphambi kokuba uqale ukwelashwa kwakho nge-doravirine, lamivudine, ne-tenofovir. Uma une-HBV futhi uthatha i-doravirine, lamivudine, ne-tenofovir, isimo sakho singase sibe sibi ngokungazelelwe lapho uyeka ukuthatha i-doravirine, i-lamivudine ne-tenofovir.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zelebhu ngaphambi, phakathi, kanye njalo izinyanga ezimbalwa ngemuva kokuyeka ukuthatha i-doravirine, lamivudine, ne-tenofovir.

Khuluma nodokotela wakho ngengcuphe (s) yokuthatha i-doravirine, i-lamivudine, ne-tenofovir.

Inhlanganisela yedoravirine, lamivudine, ne-tenofovir isetshenziselwa ukwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV) kubantu abadala abangazange belashwe ngeminye imishanguzo ye-HIV. Le nhlanganisela isetshenziselwa ukufaka indawo yokwelashwa kwamanje kubantu abathile asebethatha imishanguzo ye-HIV. UDoravirine usesigabeni semithi ebizwa nge-non-nucleoside reverse transcriptase inhibitors (NNRTIs). ILamivudine ne-tenofovir basesigabeni semithi ebizwa nge-nucleoside reverse transcriptase inhibitors (NRTIs). Inhlanganisela yedoravirine, lamivudine, ne-tenofovir isebenza ngokwehlisa inani le-HIV emzimbeni. Yize inhlanganisela ye-doravirine, i-lamivudine, ne-tenofovir ingayelaphi i-HIV, ingahle inciphise amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengokutheleleka okunzima noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko empilweni kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

Inhlanganisela yedoravirine, lamivudine, ne-tenofovir iza njengetafula elizothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye ngosuku. Thatha i-doravirine, i-lamivudine, ne-tenofovir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-doravirine, i-lamivudine, ne-tenofovir njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Inhlanganisela yedoravirine, lamivudine, ne-tenofovir iyasiza ekulawuleni ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka nokuthatha i-doravirine, i-lamivudine, ne-tenofovir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-doravirine, i-lamivudine, ne-tenofovir ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukuthatha i-doravirine, i-lamivudine, ne-tenofovir noma uphuthelwe imithamo, isimo sakho singase sibe nzima ukwelashwa. Lapho ukunikezwa kwakho kwe-doravirine, lamivudine, ne-tenofovir kuqala ukwehla, thola okuningi kudokotela noma kusokhemisi wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-doravirine, i-lamivudine, ne-tenofovir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-doravirine, lamivudine, ne-tenofovir, noma imuphi omunye umuthi, noma iziphi izithako ezikudoravirine, lamivudine, kanye namaphilisi e-tenofovir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), enzalutamide (Xtandi), mitotane (Lysodren), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifampin (Rifampin (Rifampin) eRifamate, eRifater), rifapentine (Priftin), noma eSt John's wort. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-doravirine, i-lamivudine, ne-tenofovir uma okwamanje uthatha eyodwa noma ngaphezulu yale mithi noma uthathe omunye wayo emasontweni amane edlule.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: acyclovir (Sitavig, Zovirax); ama-aminoglycosides afana ne-amikacin, i-gentamicin, i-streptomycin, ne-tobramycin; i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); cidofovir; i-ganciclovir (i-cytovene); ledipasvir / sofosbuvir (Harvoni); i-sofosbuvir / velpatasvir (i-Epculsa); i-sorbitol noma imishanguzo equkethe i-sorbitol; i-valacyclovir (iValtrex); kanye ne-valganciclovir (Valcyte). Tshela udokotela wakho uma uthatha i-rifabutin (Mycobutin) noma uyiphuzile emasontweni amane edlule. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-doravirine, lamivudine, ne-tenofovir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma unanoma yiziphi zezimo ezishiwo esigabeni SESixwayiso ESIBALULEKILE, noma uma uke waba nezinkinga zamathambo okubandakanya i-osteoporosis (isimo lapho amathambo eba mncane futhi abe buthakathaka futhi aphuke kalula), ukuphuka kwamathambo, noma izinso isifo.
• Tshela udokotela wakho uma uke waba nokutheleleka okungapheli noma okufika kudlule njenge-cytomegalovirus (CMV; ukutheleleka ngegciwane okungadala izimpawu ezigulini ezinamasosha omzimba abuthakathaka), i-mycobacterium avium complex complex (MAC; ukutheleleka kwamagciwane okungadala izimpawu ezinkulu kubantu abane-AIDS), inyumoniya, noma isifo sofuba (i-TB; uhlobo lokutheleleka kwamaphaphu); noma isifo sokuzilimaza (izimo ezikhula lapho amasosha omzimba ehlasela amaseli aphilile emzimbeni ngephutha) njengesifo se-Graves '(isimo lapho umzimba uhlasela indlala yegilo isibangela ukuthi sisebenze ngokweqile), i-polymyositis (isimo esibangela ubuthakathaka bemisipha kodwa hhayi ukuqubuka kwesikhumba), isifo se-Guillain-Barré (ubuthakathaka, ukuntekenteka, nokukhubazeka okungenzeka ngenxa yokulimala okungazelelwe kwezinzwa), kanye ne-hepatitis ezenzakalelayo (isimo lapho amaseli omzimba ehlasela isibindi).
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-doravirine, i-lamivudine, ne-tenofovir, shayela udokotela wakho. Tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma udla i-doravirine, lamivudine, ne-tenofovir.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho noma zidale ukuthi ezinye izimo zivele. Lokhu kungadala ukuthi uthuthukise izimpawu zalezo zifo noma izimo. Uma unezimpawu ezintsha noma eziya ziba zimbi phakathi nokwelashwa kwakho nge-doravirine, lamivudine, ne-tenofovir qiniseka ukutshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IDoravirine, lamivudine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi
• isicanucanu
• amaphupho angajwayelekile
• ubunzima bokulala noma ukulala
• ukozela
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuncipha kokuchama noma ukuvuvukala kwemilenze
• ubuhlungu bamathambo; ubuhlungu ezingalweni noma emilenzeni; ubuhlungu bemisipha noma ubuthakathaka; noma ukuphuka kwethambo

IDoravirine, lamivudine, ne-tenofovir kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayisusi i-desiccant (i-agent eyomisa) ebhodleleni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina i-doravirine, i-lamivudine ne-tenofovir zikhona. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho.Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UDelstrigo^®