I-Pretomanid

-Delile

• Ngaphambi kokuthatha i-pretomanid,
• I-Pretomanid ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Pretomanid isetshenziswa kanye ne-bedaquiline (Sirturo) ne-linezolid (i-Zyvox) ukwelapha isifo sofuba esimelana nemithi eminingi (MDR-TB; ukutheleleka okungathi sína okuthinta amaphaphu angenakwelashwa ngeminye imithi) kubantu abadala. I-Pretomanid isekilasini lemithi ebizwa ngama-antimycobacterials. Isebenza ngokubulala amagciwane abanga isifo sofuba.

I-Pretomanid iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku ngokudla amasonto angama-26 noma ngaphezulu. Thatha i-pretomanid ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-pretomanid njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya amaphilisi wonke ngamanzi.

Qhubeka nokuthatha i-pretomanid uze uqede incwadi kadokotela futhi ungaphuthelwa imithamo, noma ngabe uzizwa ungcono. Uma uyeka ukuthatha i-pretomanid ngokushesha noma weqe imithamo, ukutheleleka kwakho kungenzeka kungalashwa ngokuphelele futhi amabhaktheriya angamelana nemithi elwa namagciwane. Lokhu kuzokwenza ukutheleleka kwakho kube nzima ukuselapha ngokuzayo. Uzobamba iqhaza ohlelweni lokwelashwa olubhekwe ngqo ukuze uqiniseke ukuthi uphuza yonke imithi yakho njengoba uyalelwe. Kulolu hlelo, umsebenzi wezokunakekelwa kwezempilo uzokunikeza umthamo ngamunye wemithi futhi uzokubuka njengoba ugwinya umuthi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-pretomanid,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-pretomanid, bedaquiline, linezolid, noma imuphi omunye umuthi, noma iziphi izithako ezibhebheni ze-pretomanid. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: efavirenz (Sustiva, e-Atripla), methotrexate (Rheumatrex, Trexall), noma i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, e-Rifater). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-pretomanid, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort. Ungathathi i-wort yaseSt. John noma eminye imikhiqizo yamakhambi ngenkathi uthatha i-pretomanid.
• Tshela udokotela wakho uma wena noma ilungu lomndeni une-QT syndrome ende (isimo esandisa ingozi yokuhlaselwa ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzumayo), noma olunye uhlobo lokushaya kwenhliziyo okungajwayelekile noma inkinga yesigqi senhliziyo. Futhi, tshela udokotela wakho uma ngabe uke waba namazinga aphansi egazi we-calcium, i-magnesium noma i-potassium egazini lakho, isifo senhliziyo, ukwehluleka kwenhliziyo (HF; isimo lapho inhliziyo ingakwazi ukupompa igazi elanele kwezinye izingxenye zomzimba) , ukuquleka, ukutheleleka nge-HIV, noma i-thyroid, isifo sesibindi noma sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-pretomanid, shayela udokotela wakho.
• kufanele wazi ukugwema ukuphuza iziphuzo ezidakayo. Ukuphuza utshwala kwandisa ingozi yokuthi uzoba nemiphumela emibi kakhulu evela ku-pretomanid.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Pretomanid ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• induna
• ikhanda
• isilungulela
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• ukuqubuka
• ukulunywa
• ubuhlungu besisu
• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• isikhumba esomile
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukulahlekelwa isifiso sokudla, isicanucanu, amehlo aphuzi noma isikhumba, ubuhlungu endaweni engenhla kwesokudla esiswini, noma umchamo omnyama
• ubuhlungu, ukuba ndikindiki, noma ubuthakathaka ezandleni, ezinyaweni, noma kwezinye izitho zomzimba; noma izinkinga ngokulinganisela
• umbono uyashintsha
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile; ukuzwa isiyezi; noma ukuquleka
• isikhumba esiphaphathekile noma ukukhathala ngokweqile
• isicanucanu ephindaphindwayo nokuhlanza; ukuphefumula okusheshayo; ukudideka; noma uzizwe ukhathele
• ngokungazelelwe, ubuhlungu bokugwaza esifubeni, ikakhulukazi lapho uphefumulela ngaphakathi nangaphandle

I-Pretomanid ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-pretomanid. Uzodinga ukuba ne-electrocardiogram (ECG; isivivinyo esilinganisa umsebenzi kagesi wenhliziyo) ngaphambi kokwelashwa kwakho nezikhathi eziningana ngesikhathi sokwelashwa kwakho ukubona ukuthi lo muthi usithinta kanjani isigqi senhliziyo yakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.