Umlobi: William Ramirez
Usuku Lokudalwa: 18 Usepthemba 2021
Ukuvuselela Usuku: 1 Udisemba 2024
Anonim
Asenapine: Transdermal vs Sublingual?
Ividiyo: Asenapine: Transdermal vs Sublingual?

-Delile

Sebenzisa kubantu abadala asebekhulile:

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka kobuchopho okuthinta ikhono lokukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha ama-antipsychotic (imithi yokugula kwengqondo) njenge-asenapine babe nengozi eyengeziwe yokufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo bangaba nethuba elikhulu lokuba nesifo sohlangothi noma i-ministroke ngesikhathi sokwelashwa.

Ama-asenapine transdermal patches awavunyelwe yi-Food and Drug Administration (FDA) ekwelapheni izinkinga zokuziphatha kubantu abadala asebekhulile abanenkinga yokuwohloka komqondo. Khuluma nodokotela onikeze lo muthi uma wena, ilungu lomndeni, noma umuntu omnakekelayo enesifo sengqondo sokuwohloka komqondo futhi esebenzisa amabala e-asenapine transdermal. Ngeminye imininingwane vakashela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs.

Khuluma nodokotela wakho ngobungozi (s) bokusebenzisa ama-asenapine transdermal patches.

Ama-asenapine transdermal patches asetshenziselwa ukwelapha izimpawu ze-schizophrenia (ukugula kwengqondo okubangela ukuphazamiseka noma ukucabanga okungajwayelekile, ukuphelelwa yintshisekelo empilweni, kanye nemizwelo enamandla noma engafanele). I-Asenapine isekilasini lemithi ebizwa ngama-antipyychotic atypical. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.


I-asenapine yeTransdermal iza njengesichibi ukufaka esikhunjeni. Ngokuvamile kufakwa kanye ngosuku. Faka isicelo se-asenapine patch ngasikhathi sinye usuku ngalunye. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa isichibi sesikhumba se-asenapine njengoba nje kuqondisiwe. Ungayisebenzisi kaningi noma ngaphansi kunokuyalelwa ngudokotela wakho.

Udokotela wakho kungenzeka akuqale ngomthamo ophansi we-asenapine futhi akhuphule kancane umthamo wakho, hhayi kaningi ngesonto.

I-Transdermal asenapine ingasiza ukulawula izimpawu zakho kepha ngeke iselaphe isimo sakho. Qhubeka nokusebenzisa ama-asenapine patches noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa ama-asenapine patches ngaphandle kokukhuluma nodokotela wakho.

Faka isichibi esikhunjeni esihlanzekile, esomile, nesimile ngaphandle kwezinwele (phezulu ngenhla, ingalo ephezulu, isisu [indawo yesisu], noma inqulu). Khetha indawo lapho isichibi singeke sigcotshwe ngezingubo eziqinile. Ungasifaki isichibi enxebeni elivulekile noma usike, esikhunjeni esithukuthele, esibomvu, noma esikhunjeni esithintekayo ukuqubuka, ukusha, noma enye inkinga yesikhumba. Khetha indawo ehlukile usuku ngalunye ukugwema ukucasuka kwesikhumba. Qiniseka ukuthi ususa isichibi samanje ngaphambi kokufaka esisha.


Uma isikhumba sakho sicasukile noma sisha ngemuva kokufaka isichibi se-asenapine, susa isichibi bese ufaka isichibi esisha endaweni ehlukile.

Ngemuva kokufaka isichibi se-asenapine, kufanele usigqoke ngaso sonke isikhathi uze ulungele ukusisusa bese ufaka isichibi esisha. Uma isichibi sithukulula kungakafiki isikhathi sokusifaka esikhundleni saso, zama ukusicindezela sibuyele endaweni yaso ngeminwe yakho. Uma isichibi singenakucindezelwa emuva noma siwa, sisebenzise bese usebenzisa isichibi esisha endaweni ehlukile. Kodwa-ke, kufanele ususe isichibi esisha ngesikhathi obe kuhlelwe ukuthi ususe isichibi sokuqala.

Ngenkathi ugqoke isichibi se-asenapine, vikela isichibi ekushiseni okuqondile okufana namaphakethe wokushisa, izingubo zokugqoka zikagesi, okomisa izinwele, amalambu okushisa, ama-sauna, ama-tubs ashisayo, nemibhede yamanzi eshisayo. Ungageza ngenkathi ugqoke isichibi se-asenapine, kodwa ungagezi noma ubhukude.

Ukufaka isichibi, landela lezi zinyathelo:

  1. Khetha indawo lapho uzosebenzisa khona isichibi. Hlanza futhi womise indawo lapho uzofaka khona isichibi. Qiniseka ukuthi isikhumba asinampushana, uwoyela namafutha okugcoba.
  2. Khetha isichibi esikhwameni esivaliwe bese usika isikhwama ngesikhala. Qaphela ukuthi ungasiki isichibi.
  3. Susa isichibi esikhwameni bese usibamba ngendwangu yokuzivikela ebheke kuwe.
  4. Khipha isiqeshana sokuqala se-liner ohlangothini olulodwa lwesichibi. Qaphela ukuthi ungathinti uhlangothi olunamathelayo ngeminwe yakho. Umugqa wesibili we-liner kufanele uhlale unamathele esiqeshini.
  5. Cindezela i-patch ngokuqinile esikhunjeni sakho ngohlangothi olunamathele phansi.
  6. Susa umucu wesibili we-liner evikelayo bese ucindezela lonke uhlangothi olunamathelayo lwe-patch ngokuqinile esikhunjeni sakho. Qiniseka ukuthi isichibi sicindezelwe sibheke esikhunjeni ngaphandle kwamaqhuqhuva noma amafolda futhi imiphetho inamathele ngokuqinile esikhunjeni.
  7. Geza izandla zakho ngensipho namanzi ngemuva kokuphatha isichibi.
  8. Ngemuva kokuthi ugqoke isichibi amahora angama-24, sebenzisa iminwe yakho ukususa isikhafu kancane nangobumnene. Songa isichibi ngesigamu ngezinhlangothi ezinamathelayo bese usilahla ngokuphepha, lapho izingane nezilwane ezifuywayo zingafinyeleli khona.
  9. Faka isichibi esisha endaweni ehlukile ngokushesha ngokulandela izinyathelo 1 kuye ku-8.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.


Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-transdermal asenapine,

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-asenapine, noma imuphi omunye umuthi, noma iziphi izithako ezikuma-asenapine transdermal patches. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: i-alpha blocker efana ne-doxazosin (Cardura), i-prazosin (i-Minipress), ne-terazosin; i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin, eLotrel), i-captopril, i-enalapril (i-Vasotec, ngesi-Vaseretic), i-fosinopril, i-lisinopril (i-Prinivil, e-Zestoretic), i-moexipril, i-perindopril (i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon, i-Aceon I-Accupril, ngesiQuinaretic), i-ramipril (i-Altace), ne-trandolapril (i-Mavik, eTarka); ama-angiotensin receptor blockers (ama-ARB) afana ne-azilsartan (Edarbi, e-Edarbyclor), amakhandlela (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar e-Azor, e-Benicar HCT, e-Tribenzor), e-telmisartan (Micardis, e-Micardis HCT, e-Twynsta), nase-valsartan (e-Exforge HCT); ama-beta blocker anjenge-atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kanye nepropranolol (Inderal, InnoPran); ama-antibiotic athile afaka i-ciprofloxacin (Cipro), i-enoxacin (ayitholakali e-U.S.), i-gatifloxacin (iTequin) (ayitholakali e-U.S), kanye ne-moxifloxacin (Avelox); ama-antihistamine; imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Cordarone, iPacerone), i-procainamide, i-quinidine, ne-sotalol (i-Betapace, i-Sorine); isisu (‘amaphilisi amanzi’); i-fluvoxamine (i-Luvox); imithi ye-glaucoma, isifo sokuvuvukala kwamathumbu, isifo sokuhamba, i-myasthenia gravis, isifo sika-Parkinson, izilonda, noma izinkinga zomchamo; imithi yokugula kwengqondo efana ne-chlorpromazine (Thorazine), thioridazine, ne-ziprasidone (Geodon); kanye ne-paroxetine (Paxil, Pexeva). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaphinde ihlanganyele nama-asenapine transdermal patches, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
  • tshela udokotela wakho uma unesifo sesibindi. Udokotela wakho angakutshela ukuthi ungasebenzisi ama-asenapine transdermal patches.
  • utshele udokotela wakho uma wena noma omunye emndenini wakho enesifo sikashukela noma ake aba naso; uma uhuda kakhulu noma uhlanza noma ucabanga ukuthi kungenzeka uphelelwe amanzi emzimbeni; uma wake wasebenzisa izidakamizwa zasemgwaqweni noma wasebenzisa kabi imishanguzo kadokotela; futhi uma uke noma wake waba nemicabango ngokuzilimaza noma ukuzibulala; isikhathi se-QT eside (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa ngokuzuma); umfutho wegazi ophansi; isifo senhliziyo; ukwehluleka kwenhliziyo; ukushaya kwenhliziyo okuhamba kancane noma okungajwayelekile; isifo sohlangothi noma i-TIA (ministroke); ukuquleka; ukukhumuzeka kwamathambo; umdlavuza webele; izinga eliphansi lamaseli amhlophe egazini lakho noma ukwehla kwamaseli amhlophe egazi okubangelwa umuthi owuthathile; izinga eliphansi le-potassium noma i-magnesium egazini lakho; i-dyslipidemia (amazinga aphezulu e-cholesterol); unenkinga yokugcina ibhalansi yakho; noma isiphi isimo esenza kube nzima ukuthi usigwinye; noma isifo senhliziyo.
  • Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, noma uma uhlela ukukhulelwa noma ukuncelisa. Uma ukhulelwa ngenkathi usebenzisa i-transdermal asenapine, shayela udokotela wakho. I-asenapine yeTransdermal ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma isetshenziswa ezinyangeni zokugcina zokukhulelwa.
  • uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-transdermal asenapine.
  • kufanele wazi ukuthi i-asenapine ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
  • buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi usebenzisa i-transdermal asenapine. Utshwala bungenza imiphumela emibi ye-asenapine ibe yimbi kakhulu.
  • kufanele wazi ukuthi i-transdermal asenapine ingadala isizungu, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala. Lokhu kuvame kakhulu lapho uqala ukusebenzisa ama-asenapine transdermal patches. Ukusiza ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
  • kufanele wazi ukuthi i-asenapine ingenza kube nzima ukuthi umzimba wakho uphole lapho kushisa kakhulu. Ngenkathi usebenzisa i-transdermal asenapine, kufanele ugweme ukuzivocavoca ngokweqile, uhlale ngaphakathi ngangokunokwenzeka futhi ugqoke kancane lapho kushisa, uhlale elangeni, futhi uphuze uketshezi oluningi.
  • kufanele wazi ukuthi ungathola i-hyperglycemia (ukwanda kushukela wakho wegazi) ngenkathi usebenzisa lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukusebenzisa i-transdermal asenapine noma imishanguzo efanayo kungandisa le ngozi. Tshela udokotela wakho ngokushesha uma unezinye zalezi zimpawu ezilandelayo ngenkathi usebenzisa i-asenapine ye-transdermal: ukoma ngokweqile, ukuchama kaningi, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Faka isichibi esilahlekile ngokushesha nje lapho usikhumbula. Kodwa-ke, kusamele ususe isichibi ngesikhathi sakho esivamile sokususa i-patch. Uma sekusondele isikhathi se-patch elandelayo, weqa isichibi esilahlekile bese uqhubeka nesimiso sakho sokulinganisa okujwayelekile. Ungafaki ama-patches angeziwe ukwenza umthamo ongabanjwanga.

I-asenapine yeTransdermal ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ukoma, ububomvu, ukulunywa, ukuxebuka, ukuvuvukala, ukucasuka, ubunzima, ubuhlungu, noma ukungakhululeki endaweni yesicelo
  • umlomo owomile
  • ukuqunjelwa
  • isifo sohudo
  • ukuhlanza
  • isilungulela
  • ukwanda kwesifiso sokudla
  • ikhanda
  • ukuzuza kwesisindo
  • ukulahlekelwa umuzwa ezindebeni noma emlonyeni
  • isiyezi, ukuzizwa ungagxilile, noma unenkinga yokugcina ibhalansi yakho
  • ukukhathala ngokweqile
  • ukungabi namandla
  • ukungahlaliseki noma isifiso esiqhubekayo sokuqhubeka nokunyakaza
  • ubuhlungu bamalunga, izingalo, noma imilenze

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIKHETHEKILE SOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

  • isifuba
  • ukuqubuka
  • ukulunywa
  • ukuphefumula kanzima noma ukugwinya
  • ukuvuvukala kobuso, umphimbo, ulimi, izindebe, noma amehlo
  • ukushaqeka
  • isifuba
  • imfiva
  • ukuqina kwemisipha noma ubuhlungu
  • ukudumba noma ukuqina kwemisipha yentamo
  • ukudideka
  • ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
  • ukujuluka
  • ukunyakaza okungalawuleki kwezingalo, imilenze, ubuso, umlomo, ulimi, umhlathi, izindebe, noma izihlathi
  • ukuwa
  • isithuthwane
  • umphimbo obuhlungu, amakhaza, ukukhwehlela, nezinye izimpawu zokutheleleka

Izindwangu ze-Asenapine zingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Lahla noma iziphi iziqeshana eziphelelwe yisikhathi noma ezingasadingeki ngokuvula isikhwama ngasinye, ugoqe isichibi ngasinye ngesigamu ngamacala anamathelayo. Beka isichibi esigoqiwe esikhwameni sokuqala bese usilahla ngokuphepha, lapho izingane nezilwane ezifuywayo bengenakufinyelela kuzo.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Uma othile egwinya, ehlafuna, noma encela iziqeshana ze-asenapine, shayela isikhungo sakho sendawo yokulawula ubuthi ku-1-800-222-1222. Uma isisulu siwile noma singaphefumuli, shayela abezimo eziphuthumayo zendawo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

  • ukudideka
  • ukuyaluza

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Isisindo sakho kufanele sihlolwe njalo ngenkathi uthola lo muthi.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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Kugcine ukubuyekezwa - 04/15/2020

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