Inaliti yeDaratumumab neHyaluronidase-fihj

-Delile

• Ngaphambi kokuthola umjovo we-daratumumab ne-hyaluronidase-fihj,
• Umjovo we-Daratumumab ne-hyaluronidase-fihj ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisohlwini lwe-HOW section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Daratumumab ne-hyaluronidase-fihj usetshenziswa neminye imithi yokwelapha i-myeloma eminingi (uhlobo lomdlavuza womnkantsha) kubantu abadala abasanda kutholakala abangakwazi ukuthola ezinye izindlela zokwelashwa. Umjovo we-Daratumumab ne-hyaluronidase-fihj usetshenziswa futhi ngokuhlangana neminye imithi yokwelapha i-myeloma eminingi kubantu abadala ebuyile noma engakathuthuki ngemuva kokunye ukwelashwa. Lo muthi ubuye usetshenziselwe wedwa ukwelapha abantu abadala abane-myeloma eminingi abathole okungenani imigqa emithathu yokwelashwa ngeminye imithi futhi abangazange baphathwe ngempumelelo. UDaratumumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokusiza umzimba ukuthi unciphise noma umise ukukhula kwamangqamuzana omdlavuza. IHyaluronidase-fihj iyi-endoglycosidase. Kuyasiza ukugcina i-daratumumab emzimbeni isikhathi eside ukuze umuthi ube nomthelela omkhulu.

Umjovo we-Daratumumab ne-hyaluronidase-fihj uza njengesisombululo (uketshezi) sokujovwa ngomgogodla (ngaphansi kwesikhumba) esiswini (esiswini) ngaphezulu kwemizuzu emi-3 kuye kwemi-5. Ubude bokwelashwa kwakho buzoya ngesimo sakho nokuthi umzimba wakho uphendula kahle kanjani ekwelashweni.

Udokotela noma umhlengikazi uzokubheka eduze ngenkathi uthola umuthi futhi ngemuva kwalokho aqiniseke ukuthi awuphenduli ngokuqinile emithini. Uzonikezwa eminye imithi yokusiza ukuvimbela nokwelapha ukusabela ku-daratumumab ne-hyaluronidase-fihj ngaphambi nangemva kokuthola imithi yakho. Tshela udokotela wakho noma umhlengikazi ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ubunzima bokuphefumula noma ukuphefumula okuncane, ubuhlungu besifuba, isifuba, ukuqina komphimbo nokucasula, ukukhwehlela, ukuphuma kwamakhala noma ikhala eligcwele, ikhanda elibuhlungu, ukulunywa, isicanucanu, ukuhlanza, umkhuhlane, ukugodola , ukuqubuka, isifuba, noma isiyezi noma ikhanda elikhanyayo.

Udokotela wakho angamisa ukwelashwa kwakho okwesikhashana noma unomphela. Lokhu kuncike ekutheni umuthi usebenza kanjani kuwe kanye nemiphumela emibi oyitholayo. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-daratumumab ne-hyaluronidase-fihj. Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-daratumumab ne-hyaluronidase-fihj,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-daratumumab, i-hyaluronidase-fihj, noma imiphi eminye imithi, noma iziphi izithako ze-daratumumab ne-hyaluronidase-fihj injection. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nezinsini (ukuqubuka okubuhlungu okwenzeka ngemuva kokutheleleka nge-herpes zoster noma inkukhu), i-hepatitis B (igciwane elithelela isibindi futhi lingadala ukulimala kwesibindi), noma izinkinga zokuphefumula.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa ngesikhathi ukwelashwa kwakho nge-daratumumab ne-hyaluronidase-fihj futhi okungenani izinyanga ezintathu ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezinhlobo zokulawulwa kokuzalwa okuzokusebenzela. Uma ukhulelwa ngenkathi uthola umjovo we-daratumumab ne-hyaluronidase-fihj, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-daratumumab ne-hyaluronidase-fihj.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Daratumumab ne-hyaluronidase-fihj ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• isifo sohudo
• ukuhlanza
• isicanucanu
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• ukukhathala
• ubunzima bokulala noma ukulala
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ukuvuvukala kwezandla, amaqakala, noma izinyawo
• ukuhlungu obusemhlane
• ukulunywa, ukuvuvukala, ukulinyazwa, noma ukubomvu kwesikhumba endaweni yomjovo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisohlwini lwe-HOW section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukulimaza noma ukopha okungavamile
• isikhumba esiphaphathekile, ukukhathala, noma ukuphefumula okuncane
• amehlo aphuzi noma isikhumba; umchamo omnyama; noma ubuhlungu noma ukungaphatheki kahle endaweni engaphezulu yesisu

Umjovo we-Daratumumab ne-hyaluronidase-fihj ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho kumjovo we-daratumumab ne-hyaluronidase-fihj.

I-Daratumumab ne-hyaluronidase-fihj kungathinta imiphumela yokuhlolwa kwegazi ngesikhathi sokwelashwa kwakho futhi kuze kube izinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Ngaphambi kokumpontshelwa igazi, tshela udokotela wakho kanye nabasebenzi baselabhorethri ukuthi uthola noma uthola umjovo we-daratumumab ne-hyaluronidase-fihj. Udokotela wakho uzokwenza ukuhlolwa kwegazi ukufanisa uhlobo lwegazi lakho ngaphambi kokuba uqale ukwelashwa nge-daratumumab ne-hyaluronidase-fihj.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-daratumumab ne-hyaluronidase-fihj.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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