Umjovo weLurbinectedin

-Delile

• Ngaphambi kokuthola umjovo we-lurbinectedin,
• I-Lurbinectedin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Lurbinectedin usetshenziselwa ukwelapha umdlavuza omncane wamaseli wamaphaphu (i-SCLC) osabalalele kwezinye izingxenye zomzimba futhi awuzange uthuthuke ngesikhathi nangemuva kokwelashwa nge-platinum chemotherapy. Umjovo weLurbinectedin usesigabeni semithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

Umjovo weLurbinectedin uza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngaphezu kwemizuzu engama-60 ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa kanye ezinsukwini ezingama-21. Udokotela wakho uzonquma ukuthi uzoyithola kangaki i-lurbinectedin ngokuya ngempendulo yomzimba wakho kulo muthi.

Udokotela wakho kungadingeka ukuthi ayeke ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho ngomjovo we-lurbinectedin.

Udokotela wakho uzokunika imithi yokuvikela isicanucanu nokuhlanza ngaphambi kokuthola umthamo ngamunye we-lurbinectedin.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-lurbinectedin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-lurbinectedin, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-lurbinectedin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela noma engabhaliswanga, amavithamini, noma izithako zokudla okunempilo ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo yokubulala amagciwane efana ne-fluconazole (Diflucan), i-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole (i-Nizoral), ne-voriconazole (i-Vfend); i-clarithromycin (i-Biaxin, i-Prevpac); i-diltiazem (Cardizem, Dilacor, Tiazac, abanye); i-erythromycin (E-mycin, Ery-Tab, abanye); imishanguzo ethile ye-HIV efana ne-efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra), ne-saquinavir (Invirase); nefazodone; i-pioglitazone (Actos, e-Oseni); i-rifabutin (i-Mycobutin); i-prednisone; i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); imithi ethile yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Tegretol, abanye), phenobarbital, ne-phenytoin (Dilantin, Phenytek); kanye ne-verapamil (Calan, Verelan). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-lurbinectedin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola umjovo we-lurbinectedin. Udokotela wakho angenza isivivinyo sokukhulelwa ukuze aqiniseke ukuthi awukhulelwe ngaphambi kokuthola umjovo we-lurbinectedin. Uma ungowesifazane, kufanele usebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa kwakho nezinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa kwenu nezinyanga ezine ngemuva komthamo wakho wokugcina. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola umjovo we-lurbinectedin, shayela udokotela wakho. Umjovo we-Lurbinectedin ungalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola umjovo we-lurbinectedin futhi okungenani amasonto ama-2 ngemuva komthamo wakho wokugcina.

Ungadli i-grapefruit noma uphuze ijusi lamagilebhisi ngenkathi uthola lo muthi.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti yokuthola umthamo we-lurbinectedin.

I-Lurbinectedin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala
• isicanucanu
• ukuhlanza
• ukuqunjelwa
• isifo sohudo
• ukulahlekelwa isifiso sokudla
• ubuhlungu bemisipha
• ikhanda
• ukuluma, ukuba ndikindiki, nobuhlungu ezandleni nasezinyaweni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu besifuba
• ukuphelelwa umoya
• ukunyakaza kwamathumbu anombala okhanyayo, ukuphuzi kwesikhumba noma kwamehlo, ukulahlekelwa isifiso sokudla, ukopha okungavamile noma ukulimaza, umchamo omnyama ophuzi noma onsundu, noma ubuhlungu engxenyeni engenhla yesokudla
• umkhuhlane, ukukhwehlela, ukubanda, noma ezinye izimpawu zokutheleleka
• ukukhathala noma isikhumba esiphaphathekile

I-Lurbinectedin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-lurbinectedin.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-lurbinectedin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Zepzelca^®