I-Relugolix

-Delile

• Ngaphambi kokuthatha i-relugolix,
• I-Relugolix ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Relugolix isetshenziselwa ukwelapha umdlavuza wesibeletho osezingeni eliphakeme (umdlavuza oqala ku-prostate [indlala yokuzala yowesilisa]) kubantu abadala. I-Relugolix isekilasini lemithi ebizwa ngokuthi i-gonadotropin-releasing hormone (GnRH) antagonists. Isebenza ngokunciphisa inani le-testosterone (i-hormone yowesilisa) ekhiqizwa ngumzimba. Lokhu kunganciphisa noma kumise ukusabalala kwamangqamuzana omdlavuza wesibeletho adinga i-testosterone ukuthi ikhule.

I-Relugolix iza njenge-tablet ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye ngosuku. Thatha i-relugolix ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-relugolix njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-relugolix,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-relugolix, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-relugolix. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Equetro, Tegretol, Teril), clarithromycin; umqeqeshi womzimba; cyclosporine (Neoral, Sandimmune), erythromycin (E.E.S., E-Mycin, Erythrocin), ketoconazole, rifampin (Rifadin, Rimactane, eRifamate, eRifater), ritonavir (Norvir), noma verapamil (Calan, Isoptin, Verelan). Eminye imithi eminingi ingase futhi ihlanganyele ne-relugolix, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ngabe uke waba ne-QT syndrome ende noma (wake waba nenkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa ngokuzuma); amazinga aphezulu noma aphansi we-calcium, i-potassium, i-magnesium, noma i-sodium egazini lakho; noma ukwehluleka kwenhliziyo.
• kufanele wazi ukuthi i-relugolix isetshenziselwa amadoda kuphela. Abesifazane akufanele bathathe le mithi, ikakhulukazi uma bekhulelwe noma bengakhulelwa noma bencelisa. Uma ungowesilisa futhi umlingani wakho wesifazane angakhulelwa, kufanele usebenzise izindlela zokuvimbela inzalo ezisebenzayo ngesikhathi sokwelashwa kanye namasonto ama-2 ngemuva komthamo wokugcina. I-Relugolix ingalimaza umbungu.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala emadodeni. Khuluma nodokotela wakho ngezingozi zokuthatha i-relugolix.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa ngumthamo ngaphansi kwamahora ayi-12, thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Kodwa-ke, uma uphuthelwa umthamo ngaphezu kwamahora we-12, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Uma uphuthelwa izinsuku ezingaphezu kwezingu-7 zokwelashwa, khuluma nodokotela wakho ngaphambi kokuqala ukukuthatha futhi. Kuzodingeka uqale kabusha ukuyithatha kumthamo ophakeme ekuqaleni.

I-Relugolix ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukushisa okushisayo
• ukuqhuma isikhumba
• ukujuluka
• ukuzuza kwesisindo
• kwehle isifiso sobulili noma ikhono
• ubuhlungu bemisipha, emuva, obuhlangene, noma bethambo
• ukukhathala
• isifo sohudo
• ukuqunjelwa
• ubunzima bokulala noma ukulala
• ukudana

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isiyezi; ukuquleka; ukushaya kwenhliziyo; noma ubuhlungu besifuba
• ubuhlungu besifuba noma ingcindezi; noma ubuhlungu ezingalweni, emhlane, entanyeni, noma emhlathini
• ukuba ndikindiki okungazelelwe noma ukuba buthakathaka kobuso, ingalo, noma umlenze (ikakhulukazi ohlangothini olulodwa lomzimba); ukudideka okungazelelwe; ukukhathazeka ukukhuluma noma ukuqonda; inkathazo engazelelwe yokubona kwelinye noma kuwo womabili amehlo; noma ukuhamba enkingeni ngokungazelelwe, isiyezi, ukulahlekelwa ibhalansi noma ukuxhumanisa

I-Relugolix ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (iphakethe elincane elifakiwe nemithi yokwamukela umswakama).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-relugolix.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi usebenzisa i-relugolix.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Orgovyx^®