I-TRT: Iqiniso elihlukanisayo kusuka kuFiction

-Delile

• Yini i-TRT?
• Kungani i-T incipha ngeminyaka?
• Ngazi kanjani ukuthi ngine-T ephansi?
• Ilawulwa kanjani i-TRT?
• I-TRT isetshenziswa kanjani kwezokwelapha?
• Yikuphi ukusetshenziswa okungeyona kwezokwelapha kwe-TRT?
• Kubiza malini i-TRT?
• Yigcine isemthethweni (futhi iphephile)
• Ingabe zikhona izingozi ezixhunyaniswe ne-TRT?
• Okubalulekile

Yini i-TRT?

I-TRT isichasiso sokwelapha i-testosterone therapy, kwesinye isikhathi ibizwa ngokuthi ukwelashwa okufaka esikhundleni se-androgen. Isetshenziselwa ukwelapha amazinga aphansi e-testosterone (T), angenzeka ngeminyaka noma ngenxa yesimo sezempilo.

Kepha kuya ngokuya kwanda ngokusetshenziswa okungeyona eyezokwelapha, kufaka phakathi:

• ukuthuthukisa ukusebenza kocansi
• ukuthola amazinga aphezulu wamandla
• ukwakha imisipha yokwakha umzimba

Olunye ucwaningo lukhombisa ukuthi i-TRT ingakusiza ukuthi ufeze ezinye zalezi zinhloso. Kepha kunezihibe ezithile. Ake singene kulokho okwenzeka ngqo emazingeni akho we-T njengoba ukhula nokuthi yini ongayilindela ngokweqiniso ku-TRT.

Kungani i-T incipha ngeminyaka?

Umzimba wakho ngokwemvelo ukhiqiza u-T omncane njengoba ukhula. Ngokusho kwendatshana eku-American Family Physician, ukukhiqizwa kwe-T kwesilisa okujwayelekile kwehla cishe ngephesenti elilodwa kuya kwamabili unyaka ngamunye.

Konke lokhu kuyingxenye yenqubo yemvelo ngokuphelele eqala ngasekupheleni kweminyaka engama-20 noma ekuqaleni kweminyaka engama-30:

1. Njengoba ukhula, amasende akho akhiqiza u-T omncane.
2. Ukwehliswa kwamasende T kubangela ukuthi i-hypothalamus yakho ikhiqize i-hormone engatheni ekhulula i-gonadotropin (GnRH).
3. Ukwehlisa i-GnRH kubangela ukuthi indlala yakho ye-pituitary yenze i-hormone engaphansi ye-luteinizing (LH).
4. Imiphumela eyehlisiwe ye-LH kumkhiqizo owehlisiwe ophelele we-T.

Lokhu kwehla kancane kancane kwe-T kaningi akubangeli zimpawu ezibonakalayo. Kepha ukwehla okukhulu kwamazinga we-T kungadala:

• ukushayela ucansi okuphansi
• ama-erections ambalwa okuzenzekelayo
• ukungasebenzi kahle kwe-erectile
• kwehlise isibalo sesidoda noma ivolumu
• inkathazo yokulala
• ukulahleka okungajwayelekile kwemisipha namathambo
• ukuzuza kwesisindo okungaqondakali

Ngazi kanjani ukuthi ngine-T ephansi?

Ukuphela kwendlela yokwazi ukuthi unayo ngempela i-T ephansi ukubona umhlinzeki wezokunakekelwa kwezempilo esivivinyweni sezinga le-testosterone. Lokhu ukuhlolwa kwegazi okulula, futhi abahlinzeki abaningi bakudinga ngaphambi kokuchaza i-TRT.

Ungadinga ukwenza isivivinyo kaningana ngoba amazinga we-T athinteka yizici ezahlukahlukene, njenge:

• ukudla
• izinga lokuqina
• isikhathi sosuku isivivinyo sesenziwe
• imithi ethile, njenge-anticonvulsants ne-steroids

Nakhu ukwehla kwamazinga we-T ejwayelekile emadodeni amadala aqala eminyakeni yobudala engama-20:

Uma amazinga akho we-T ephansi kancane ngeminyaka yakho, mhlawumbe awudingi i-TRT.Uma ziphansi kakhulu, umhlinzeki wakho kungenzeka enze ukuhlolwa okwengeziwe ngaphambi kokuncoma i-TRT.

Ilawulwa kanjani i-TRT?

Kunezindlela eziningi zokwenza i-TRT. Okukhethwa kukho okuhle kuzoya ngezidingo zakho zezokwelapha kanye nendlela yakho yokuphila. Ezinye izindlela zidinga ukuphathwa nsuku zonke, kanti ezinye zidinga ukwenziwa njalo ngenyanga.

Izindlela ze-TRT zifaka:

• imithi yomlomo
• imijovo yemisipha
• Ama-patdermal patches
• okhilimu bezindaba

Kukhona nohlobo lwe-TRT olubandakanya ukuhlikihla i-testosterone ezinsinini zakho kabili ngosuku.

I-TRT isetshenziswa kanjani kwezokwelapha?

I-TRT ngokwesiko isetshenziselwa ukwelapha i-hypogonadism, eyenzeka lapho ama-testes akho (abizwa nangokuthi ama-gonads) engakhiqizi i-testosterone eyanele.

Kunezinhlobo ezimbili ze-hypogonadism:

• I-hypogonadism eyinhloko. Imiphumela ephansi ye-T ivela ezindabeni ngama-gonads akho. Bathola amasiginali ebuchosheni bakho ukwenza i-T kepha abakwazi ukuwakhiqiza.
• I-hypogonadism emaphakathi (yesibili). Imiphumela ephansi ye-T ivela ezindabeni ze-hypothalamus noma i-pituitary gland yakho.

I-TRT isebenza ukwenzela i-T engakhiqizwa ama-testes akho.

Uma une-hypogonadism yangempela, i-TRT inga:

• thuthukisa umsebenzi wakho wezocansi
• khulisa isibalo sakho sesidoda nevolumu
• ukwandisa amazinga amanye amahomoni asebenzisana ne-T, kufaka phakathi i-prolactin

I-TRT ingasiza futhi ukulinganisela amazinga we-T angavamile abangelwa:

• izimo ezizimele
• ukuphazamiseka kofuzo
• izifo ezilimaza izitho zakho zobulili
• amasende angafuneki
• ukwelashwa ngemisebe yomdlavuza
• ukuhlinzwa kwezitho zocansi

Yikuphi ukusetshenziswa okungeyona kwezokwelapha kwe-TRT?

Amazwe amaningi, kubandakanya ne-United States, awavumeli abantu ukuthi bathenge ngokusemthethweni izithasiselo ze-T ze-TRT ngaphandle kwencwadi kadokotela.

Noma kunjalo, abantu bafuna i-TRT ngezizathu eziningi ezingezona ezokwelapha, njenge:

• ukuncipha
• ukwandisa amazinga wamandla
• ukukhulisa idrayivu yezocansi noma ukusebenza
• ukukhulisa ukubekezela kwemidlalo
• ukuthola imisipha eyengeziwe yokwakha umzimba

I-TRT impela ikhonjisiwe ukuthi inezinye zalezi zinzuzo. Isibonelo, kuphethwe ukuthi kukhulise ngempumelelo amandla emisipha emadodeni aphakathi nendawo nangaphezulu.

Kepha i-TRT inezinzuzo ezimbalwa ezifakazelwe kubantu, ikakhulukazi abesilisa abancane, abanamazinga ajwayelekile noma aphezulu eT. Futhi izingozi zingadlula izinzuzo. Ucwaningo oluncane luka-2014 luthole ukuxhumana phakathi kwamazinga aphezulu we-T nokukhiqizwa kwesidoda okuphansi.

Futhi, ukusebenzisa i-TRT ukuthola umkhawulo wokuncintisana kwezemidlalo kubhekwa njenge- "doping" yizinhlangano eziningi zobungcweti, futhi iningi likubheka njengezizathu zokunqanyulwa kulo mdlalo.

Esikhundleni salokho, cabanga ukuzama ezinye izindlela zokwengeza u-T. Nanka amathiphu ayisishiyagalombili wokuqalisa.

Kubiza malini i-TRT?

Izindleko ze-TRT ziyehluka ngokuya ngohlobo onqunyelwe lona. Uma unomshuwalense wezempilo futhi udinga i-TRT ukwelapha isimo sempilo, cishe ngeke ukhokhe izindleko ezigcwele. Izindleko zangempela zingahluka ngokuya ngendawo yakho nokuthi ngabe kukhona inguqulo ejwayelekile etholakalayo.

Ngokuvamile, ungalindela ukukhokha noma yikuphi kusuka ku- $ 20 kuya ku- $ 1,000 ngenyanga. Izindleko zangempela zincike ebangeni lezici, kufaka phakathi:

• indawo okuyo
• uhlobo lomuthi
• indlela yokuphatha
• noma ngabe kukhona uhlobo olujwayelekile olutholakalayo

Lapho ucabangela izindleko, khumbula ukuthi i-TRT imane ikhuphule amazinga akho e-T. Ngeke iphathe imbangela eyisisekelo ye-T yakho ephansi, ngakho-ke ungadinga ukwelashwa impilo yonke.

Yigcine isemthethweni (futhi iphephile)

Khumbula, akukho emthethweni ukuthenga i-T ngaphandle kwencwadi kadokotela emazweni amaningi. Uma ubanjwa wenza kanjalo, ungabhekana nemiphumela emibi yezomthetho.

Futhi, iT ithengiswa ngaphandle kwamakhemisi asemthethweni ayilawulwa. Lokhu kusho ukuthi kungenzeka ukuthi uthenga i-T exutshwe nezinye izithako ezingekho ohlwini lwelebula. Lokhu kungaba yingozi noma kusongele impilo uma unalelgi kunoma iziphi zalezo zithako.

Ingabe zikhona izingozi ezixhunyaniswe ne-TRT?

Ochwepheshe basazama ukuqonda ngokugcwele izingozi nemiphumela emibi ye-TRT. Ngokuya ngeHarvard Health, izifundo eziningi ezikhona zinemikhawulo, njengokuncane ngosayizi noma ukusebenzisa imithamo emikhulu kunokujwayelekile yeT.

Ngenxa yalokhu, kusenempikiswano mayelana nezinzuzo nobungozi obuxhumene ne-TRT. Isibonelo, kuthiwe kukhulisa futhi kunciphise ubungozi bezinhlobo ezithile zomdlavuza.

Iphephabhuku i-Therapeutic Advances in Urology liphakamisa ukuthi eminye yale mibono engqubuzanayo ingumphumela wokusakazwa ngokweqile kwabezindaba, ikakhulukazi e-United States.

Ngaphambi kokuzama i-TRT, kubalulekile ukuhlala phansi nomhlinzeki wakho wezokunakekelwa kwempilo bese ubheka yonke imiphumela emibi engaba khona kanye nezingozi. Lokhu kungafaka:

• ubuhlungu besifuba
• ukuphefumula kanzima
• ubunzima bokukhuluma
• ukubala kwesidoda okuphansi
• polycythemia vera
• kwehlise i-cholesterol ye-HDL ("enhle")
• isifo senhliziyo
• ukuvuvukala ezandleni noma emilenzeni
• unhlangothi
• i-benign prostatic hyperplasia (i-prostate ekhulisiwe)
• ukulala ubuthongo
• izinduna noma ukuqhuma kwesikhumba okufanayo
• i-vein thrombosis ejulile
• embolism yamaphaphu

Akufanele ungene ku-TRT uma usuvele usengcupheni yanoma yiziphi izimo ezibhalwe ngenhla.

Okubalulekile

I-TRT sekuyisikhathi eside iyindlela yokwelashwa kubantu abane-hypogonadism noma izimo ezihambisana nokukhiqizwa kwe-T okuncishisiwe. Kepha izinzuzo zayo kulabo abangenawo umbandela oyisisekelo azicaci kangako, naphezu kwawo wonke ama-hype.

Khuluma nodokotela wakho ngaphambi kokuthatha noma iziphi izithako ze-T noma imithi. Bangakusiza ukuthi unqume ukuthi ngabe izinhloso zakho nge-TRT ziphephile yini futhi zinengqondo.

Kubalulekile futhi ukuthi ubhekwe ngongoti bezokwelapha njengoba uthatha izithasiselo ze-T ukuze uqaphele noma yiziphi izimpawu ezingafuneki noma imiphumela emibi engahle yenzeke ngesikhathi sokwelashwa.