I-Rifampin

-Delile

• Ngaphambi kokuthatha i-rifampin,
• I-Rifampin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Rifampin isetshenziswa neminye imithi yokwelapha isifo sofuba (i-TB; ukutheleleka okunzima okuthinta amaphaphu futhi kwesinye isikhathi nezinye izingxenye zomzimba). I-Rifampin nayo isetshenziselwa ukwelapha abanye abantu abanayo I-Neisseria meningitidis (uhlobo lwama-bacteria olungadala ukutheleleka okukhulu okubizwa nge-meningitis) ezifweni nasemakhaleni abo. Laba bantu abakaze babe nezimpawu zalesi sifo, kanti le ndlela yokwelapha isetshenziselwa ukuvikela ukuthi bangatheleleli abanye abantu. I-Rifampin akufanele isetshenziselwe ukwelapha abantu abanezimpawu ze-meningitis. URifampin usesigabeni semithi ebizwa ngama-antimycobacterials. Isebenza ngokubulala amabhaktheriya abangela ukutheleleka.

Ama-antibiotic afana ne-rifampin ngeke asebenzele imikhuhlane, umkhuhlane, noma okunye ukutheleleka ngegciwane. Ukusebenzisa ama-antibiotic lapho kungadingeki kwandisa ingozi yakho yokuthola ukutheleleka kamuva okuphikisana nokwelashwa kwama-antibiotic.

URifampin uza njengephilisi elizothathwa ngomlomo. Kufanele ithathwe ngengilazi egcwele yamanzi esiswini esingenalutho, ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla. Lapho i-rifampin isetshenziselwa ukwelapha isifo sofuba, iphuzwa kanye ngosuku. Lapho i-rifampin isetshenziselwa ukuvimbela ukusabalala kwe- I-Neisseria meningitidis amabhaktheriya kwabanye abantu, kuthathwa kabili nsuku zonke izinsuku ezimbili noma kanye nsuku zonke izinsuku ezine. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-rifampin njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Tshela udokotela noma usokhemisi wakho uma ungakwazi ukugwinya amaphilisi. Usokhemisi wakho angakulungisela uketshezi okufanele uluthathe esikhundleni salokho.

Uma uthatha i-rifampin ukwelapha isifo sofuba, udokotela wakho angakutshela ukuthi uthathe i-rifampin izinyanga ezimbalwa noma ngaphezulu. Qhubeka uthathe i-rifampin uze uqedele imishanguzo noma ngabe uzizwa ungcono, futhi uqaphele ukuthi ungaphuthelwa imithamo. Uma uyeka ukuthatha i-rifampin maduzane, ukutheleleka kwakho kungenzeka kungalashwa ngokuphelele futhi amabhaktheriya angamelana nemithi elwa namagciwane. Uma uphuthelwa imithamo ye-rifampin, ungaqala ukuba nezimpawu ezingathandeki noma ezimbi lapho uqala ukuthatha umuthi futhi.

I-Rifampin kwesinye isikhathi isetshenziswa ukwelapha izifo ezibangelwa ezinye izinhlobo zebhaktheriya nokuvikela ukutheleleka kubantu abebesondelene kakhulu nabantu abanezifo ezithile ezibucayi ezibangelwa amagciwane. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-rifampin,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-rifampin, i-rifabutin (i-Mycobutin), i-rifapentine (i-Priftin), noma imuphi omunye umuthi, noma iziphi izithako ezikuma-capsule e-rifampin. Buza udokotela wakho noma usokhemisi uhlu lwezithako.
• Tshela udokotela wakho uma ngabe uthatha noma imuphi wale mithi elandelayo: (Invirase) kuhlanganisiwe. Udokotela wakho mhlawumbe uzokutshela ukuthi ungayithathi i-rifampin uma usebenzisa noma iyiphi yale mithi. Uma uthatha i-rifampin futhi udinga ukuthatha i-praziquantal (i-Biltricide), kufanele ulinde okungenani amasonto ama-4 ngemuva kokuyeka ukuthatha i-rifampin ngaphambi kokuba uqale ukuthatha i-praziquantel.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); ama-antifungals afana ne-fluconazole (Diflucan), i-itraconazole (i-Onmel, i-Sporanox), ne-ketoconazole; i-atovaquone (iMepron, eMalarone); ama-barbiturates afana ne-phenobarbital; ama-beta blocker anjenge-atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), nepropranolol (Inderal, Innopran); ama-calcium channel blocker afana ne-diltiazem (Cardizem, Cartia, Tiazac), nifedipine (Adalat, Procardia), ne-verapamil (Calan, Verelan); i-chloramphenicol; i-clarithromycin (i-Biaxin); i-cyclosporine (Gengraf, Neoral, Sandimmune); daclatasvir (Daklinza); dapsone; diazepam (Valium); i-doxycycline (i-Monodox, i-Oracea, i-Vibramycin); i-efavirenz (Sustiva); i-enalapril (i-Vaseretic); ama-antibiotic e-fluoroquinolone njenge-ciprofloxacin (Cipro) ne-moxifloxacin (Avelox); gemfibrozil (Lopid); i-haloperidol (iHaldol); izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, noma imijovo); ukwelashwa kwe-hormone replacement (HRT); indinavir (Crixivan); i-irinotecan (iCamptosar); i-isoniazid (eRifater, eRifamate); i-levothyroxine (Levoxyl, Synthroid, Tirosint); losartan (Cozaar); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-digoxin (i-Lanoxin), i-disopyramide (i-Norpace), i-mexiletine, i-propafenone (i-Rythmol), ne-quinidine (e-Nuedexta); imithi yokuquleka efana ne-phenytoin (iDilantin, Phenytek); i-methadone (i-Dolophine, i-Methadose); imithi ye-narcotic yezinhlungu ezifana ne-oxycodone (i-Oxaydo, i-Xtampza) ne-morphine (i-Kadian); i-ondansetron (iZofran, iZuplenz); imithi yomlomo yesifo sikashukela efana ne-glipizide (Glucotrol), i-glyburide (i-Diabeta), ne-rosiglitazone (i-Avandia); ama-probenecid (i-Probalan); i-quinine (iQualquin); i-simvastatin (i-Flolipid, i-Zocor), i-steroids efana ne-dexamethasone (i-Decadron), i-methylprednisolone (i-Medrol) ne-prednisone; i-sofosbuvir (Sovaldi); i-tamoxifen (i-Soltamox); i-toremifene (Fareston); i-trimethoprim ne-sulfamethoxazole (Bactrim, Septra); itacrolimus (Prograf); i-theophylline (i-Elixophyllin, i-Theo-24); i-tricyclic antidepressants efana ne-amitriptyline ne-nortriptyline (Pamelor); i-zidovudine (i-Retrovir, e-Trizivir), ne-zolpidem (Ambien). Eminye imithi eminingi ingaxhumana ne-rifampin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha ama-antacids, thatha i-rifampin okungenani ihora elilodwa ngaphambi kokuthatha ama-antacids.
• Tshela udokotela wakho uma uthatha noma usebenzisa izinto zokuvimbela inzalo ze-hormonal (amaphilisi okulawula ukubeletha, amabala, izindandatho, okufakelwa kanye nemijovo). I-Rifampin inganciphisa ukusebenza kahle kokuvimbela inzalo ngama-hormonal. Kufanele usebenzise enye indlela yokulawula ukubeletha ngenkathi usebenzisa le mithi. Khuluma nodokotela wakho mayelana nokulawulwa kokuzalwa ngenkathi uthatha i-rifampin.
• Tshela udokotela wakho uma uke waba nesifo sikashukela noma i-porphyria (isimo lapho izinto ezithile zemvelo zakha khona emzimbeni futhi zingadala ubuhlungu besisu, izinguquko ekucabangeni nasekuziphatheni, noma ezinye izimpawu), noma yisiphi isimo esithinta indlala yakho ye-adrenal indlala encane eduze kwezinso ezikhiqiza izinto ezibalulekile zemvelo) noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-rifampin, shayela udokotela wakho.
• Tshela udokotela wakho uma ugqoke amalensi athambile okuthintana nawo. I-Rifampin ingadala amabala abomvu unomphela kuma-lens oxhumana nawo uma uwagqoka ngesikhathi sokwelashwa kwakho nge-rifampin.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Ungaphuthelwa imithamo ye-rifampin. Imithamo elahlekile ingakhuphula ubungozi bokuthi uzoba nemiphumela emibi kakhulu. Uma uphuthelwa umthamo, thatha umthamo owulahlekile ngokushesha uma uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese ushayela udokotela wakho. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Rifampin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuguqulwa kwesikhashana (okuphuzi, okubomvu-orange, noma umbala onsundu) kwesikhumba sakho, amazinyo, amathe, umchamo, isitulo, umjuluko nezinyembezi)
• ukulunywa
• ukuqhuma
• ikhanda
• ukozela
• isiyezi
• ukuntuleka kokuxhumana
• ubunzima bokugxila
• ukudideka
• izinguquko ekuziphatheni
• ubuthakathaka bemisipha
• ukuba ndikindiki
• ubuhlungu ezingalweni, ezandleni, ezinyaweni, noma emilenzeni
• isilungulela
• amajaqamba esiswini
• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukuhlanza
• isifo sohudo
• igesi
• izikhathi ezibuhlungu noma ezingavamile zokuya esikhathini
• umbono uyashintsha

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

• indle enamanzi noma enegazi, amajaqamba esiswini, noma imfiva ngesikhathi sokwelashwa noma izinyanga ezimbili noma ngaphezulu ngemuva kokuyeka ukwelashwa
• ukuqubuka; isifuba; imfiva; Ukugodola; ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo; ubunzima bokugwinya noma ukuphefumula; ukuphelelwa umoya; ukushaya; ama-lymph node avuvukile; Umphimbo obuhlungu; iso elibomvana; izimpawu ezinjengomkhuhlane; ukopha okungavamile noma ukulimaza; noma ukuvuvukala okuhlangene noma ubuhlungu
• isicanucanu, ukuhlanza, ukulahlekelwa isifiso sokudla, umchamo omnyama, noma ukuphuzi kwesikhumba noma kwamehlo

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

I-Rifampin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• ukulunywa
• ikhanda
• ukulahlekelwa ukwazi
• ukuphuzi kwesikhumba noma kwamehlo
• umbala onsundu ngokubomvu kwesikhumba, amathe, umchamo, indle, umjuluko nezinyembezi
• ubumnene engxenyeni engenhla yangakwesokudla yesisu
• ukuvuvukala kwamehlo noma kobuso
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• isithuthwane

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yakho ku-rifampin.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, kufaka phakathi ukuhlolwa kokuhlolwa kwezidakamizwa, tshela abasebenzi be-laboratory ukuthi uthatha i-rifampin. IRifampin ingadala imiphumela yokuhlolwa kokuhlolwa kwezidakamizwa ukuthi ibe muhle yize ungakayiphuzanga le mithi.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Rifadin^®
• I-Rimactane^®

• Ukuvuselela^® (equkethe i-Isoniazid, Rifampin)
• Isibhamu^® (equkethe i-Isoniazid, Pyrazinamide, Rifampin)