Inaliti yeThiyotepa

-Delile

• Ngaphambi kokuthola i-thiotepa,
• I-Thiotepa ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

IThiyotepa isetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza wesibeletho (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda), umdlavuza webele nowesinye. Ibuye isetshenziselwe ukuphatha ukwelashwa okulimazayo (isimo lapho uketshezi luqoqa emaphashini noma nxazonke zenhliziyo) okubangelwa izicubu zomdlavuza. UThiyotepa usesigabeni semithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

UThiyotepa uza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Kungabuye kujovwe ngaphakathi (ngaphakathi kwesisu), ngaphakathi (ngaphakathi kwesifuba), noma nge-intrapericardially (emgqeni wenhliziyo). Isheduli yokwelashwa kwakho incike esimweni sakho nokuthi uphendula kanjani ku-thiotepa.

Uma isetshenziselwa umdlavuza wesinye, i-thiotepa ifakwa (ijojowe kancane) esinyeni sakho ngokusebenzisa ithubhu noma ipayipi kanye ngesonto amasonto ama-4. Gwema uketshezi lokuphuza amahora ayisishiyagalombili kuya kwayi-12 ngaphambi kokwelashwa kwakho. Kufanele ugcine umuthi esinyeni sakho amahora amabili. Uma ungakwazi ukugcina umuthi esinyeni sakho amahora wonke ama-2, tshela umhlinzeki wakho wezokunakekelwa kwempilo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-thiotepa,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies kwi-thiotepa, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-thiotepa. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi. Udokotela wakho kungenzeka angafuni ukuthi ungatholi i-thiotepa.
• Tshela udokotela wakho ukuthi wake wathola noma uzokwelashwa ngemisebe (x-ray) noma enye i-chemotherapy futhi uma uke waba nezimo ezithile zezempilo noma wake waba nazo.
• kufanele wazi ukuthi i-thiotepa ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane, ingamisa ukukhiqizwa kwesidoda emadodeni, futhi ingadala nenzalo (kube nzima ukukhulelwa). Abesifazane abakhulelwe kufanele batshele odokotela babo ngaphambi kokuba baqale ukuthola lo muthi. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola i-thiotepa. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa kuwe noma kumlingani wakho ngesikhathi sokwelashwa kwakho ngomjovo we-thiotepa.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola i-thiotepa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Thiotepa ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• ukukhathala okungajwayelekile noma ubuthakathaka
• isiyezi
• ikhanda
• ukufiphala kwamehlo
• amehlo abuhlungu noma abomvu
• ukulahleka kwezinwele
• ubuhlungu endaweni lapho umjovo wafakwa khona

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuchama kaningi, okuphuthumayo noma okubuhlungu
• igazi emchameni
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza kwegazi; okokuhlanza okubukeka njengezizathu zekhofi
• ekhaleni

IThiyotepa ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-thiotepa.

I-Thiotepa ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza kwegazi; okokuhlanza okubukeka njengezizathu zekhofi

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-thiotepa.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Tepadina^®
• Thioplex^®¶

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.