Injection ye-Interferon Alfa-2b

-Delile

• Kusetshenziswa umjovo we-Interferon alfa-2b
• Uma une:
• Ngaphambi kokuthola umjovo we-interferon alfa-2b,
• Umjovo we-Interferon alfa-2b ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma yiziphi noma lezo ezibalwe eziXwayisweni EZIBALULEKILE noma ezigabeni EZIKHETHEKILE, Fonela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Ukujova kwe-Interferon alfa-2b kungadala noma kubhebhethekise lezi zimo ezilandelayo ezingaba zimbi noma ezisongele impilo: izifo; ukugula ngengqondo, kufaka phakathi ukudangala, izinkinga zemizwa nezokuziphatha, noma imicabango yokuzilimaza noma ukuzibulala noma ukubulala abanye; ukuphazamiseka kweschemic (izimo lapho kutholakala khona igazi elincane endaweni yomzimba) njenge-angina (ubuhlungu besifuba) noma isifo senhliziyo; nokuphazamiseka kokuzilimaza komzimba (izimo lapho amasosha omzimba ehlasela khona ingxenye eyodwa noma eziningi zomzimba ezingathinta igazi, amalunga, izinso, isibindi, amaphaphu, imisipha, isikhumba noma indlala yegilo). Tshela udokotela wakho uma unesifo; noma uma uke waba nesifo sokuzivikela komzimba, i-psoriasis (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, ama-scaly kwezinye izindawo zomzimba), systemic lupus erythematosus (SLE noma lupus; isifo sokuzivikela komzimba lapho amasosha omzimba ahlasela khona enempilo izingxenye zomzimba), i-sarcoidosis (isimo lapho ama-clump amancane amangqamuzana omzimba akha izitho ezahlukahlukene ezinjengamaphaphu, amehlo, isikhumba, nenhliziyo futhi kuphazamise ukusebenza kwalezi zitho), noma isifo samathambo (RA; isimo lapho umzimba uhlasela khona amalunga awo, ubangele ubuhlungu, ukuvuvukala, nokulahlekelwa wumsebenzi); umdlavuza; i-colitis (ukuvuvukala kwamathumbu); isifo sikashukela; isifo senhliziyo; umfutho wegazi ophakeme; amazinga aphezulu e-triglyceride (amafutha ahlobene ne-cholesterol); I-HIV (i-human immunodeficiency virus) noma i-AIDS (i-immunodeficiency syndrome); ukushaya kwenhliziyo okungajwayelekile; ukugula kwengqondo kubandakanya ukucindezeleka, ukukhathazeka, noma ukucabanga noma ukuzama ukuzibulala; noma inhliziyo, izinso, amanyikwe, noma isifo segilo.

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: uhudo olunegazi noma ukunyakaza kwamathumbu; umkhuhlane, ukubanda, ukukhwehlela nge-phlegm (amafinyila), umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka; ukuchama kaningi noma ngobuhlungu, ubuhlungu besifuba; ukushaya kwenhliziyo okungajwayelekile; ushintsho esimweni sakho sengqondo noma ekuziphatheni kwakho; ukucindezeleka; ukuqala ukusebenzisa izidakamizwa zasemgwaqweni noma utshwala futhi uma ubuzisebenzisa phambilini; ukucasuka (ukucasuka kalula); imicabango yokuzibulala noma yokuzilimaza; ukuziphatha okunolaka noma okunodlame; ukuphefumula kanzima; ubuhlungu besifuba; izinguquko ekuhambeni noma ekukhulumeni; ukunciphisa amandla noma ubuthakathaka ngakolunye uhlangothi lomzimba wakho; ukungaboni kahle noma ukulahleka kombono; ubuhlungu obukhulu besisu; ukopha okungavamile noma ukulimaza; umchamo onombala omnyama; ukunyakaza okukhanyayo okukhanyayo; noma ukwanda kwesifo somzimba.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-interferon alfa-2b.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-interferon alfa-2b futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Umjovo we-Interferon alfa-2b usetshenziselwa ukwelapha izimo eziningi.

Kusetshenziswa umjovo we-Interferon alfa-2b

• iyodwa noma ihlanganiswe ne-ribavirin (Copegus, Rebetol, Ribasphere) yokwelapha ukutheleleka okungapheli (kwesikhathi eside) kwesifo sokusha kwesibindi kohlobo C (ukuvuvukala kwesibindi okubangelwa igciwane) kubantu abakhombisa izimpawu zokulimala kwesibindi,
• ukwelapha ukutheleleka okungapheli kwe-hepatitis B (ukuvuvukala kwesibindi okubangelwa igciwane) kubantu abakhombisa izimpawu zokulimala kwesibindi,
• ukwelapha i-leukemia yeseli elinoboya (umdlavuza omhlophe wamangqamuzana egazi),
• ukwelapha izinsumpa zangasese,
• ukwelapha iKaposi’s sarcoma (uhlobo lomdlavuza oludala izicubu ezingavamile ukuba zikhule ezingxenyeni ezihlukene zomzimba) ezihlobene ne-immunodeficiency syndrome (i-AIDS),
• ukwelapha i-malignant melanoma (umdlavuza oqala kumaseli athile esikhumba) kubantu abathile abahlinziwe ukukhipha umdlavuza,
• kanye nomunye umuthi wokwelapha i-follicular non-Hodgkin's lymphoma (NHL; umdlavuza wegazi okhula kancane).

I-Interferon alfa-2b isekilasini lemithi ebizwa ngama-immunomodulators. I-Interferon alfa-2b isebenza ukwelapha igciwane le-hepatitis C (HCV) kanye ne-hepatitis B virus (HBV) ngokwehlisa inani legciwane emzimbeni. I-Interferon alfa-2b ingahle ingelaphi i-hepatitis B noma i-hepatitis C noma ikuvimbele ekubeni nezinkinga ezivela kulezi zifo ezifana ne-cirrhosis (scarring) yesibindi, ukwehluleka kwesibindi, noma umdlavuza wesibindi. Kungenzeka futhi kungavimbeli ukusakazeka kwesifo sokusha kwesibindi kohlobo B noma C kwabanye abantu. Akwaziwa kahle ukuthi i-interferon alfa-2b isebenza kanjani ukwelapha umdlavuza noma izinsumpa zangasese.

I-Interferon alfa-2b iza njenge-powder esitsheni sokuxubana noketshezi futhi njengesixazululo sokujova ngokunqamula (ngaphansi nje kwesikhumba), ngemisipha (emsipheni), ngemithambo (emthanjeni), noma ngaphakathi (kwisilonda) ). Kungcono ukujova umuthi cishe ngesikhathi esifanayo sosuku ngezinsuku zakho zomjovo, imvamisa ntambama noma kusihlwa.

Uma une:

• I-HCV, jove lo muthi kathathu noma nge-intramuscularly kathathu ngesonto.
• I-HBV, jove lo muthi ngokuncipha noma nge-intramuscularly kathathu ngesonto imvamisa amasonto ayi-16.
• i-leukemia enoboya obuningi, ujove umuthi kungaba nge-intramuscularly noma ngaphansi kwesikhumba amahlandla ama-3 ngeviki kuze kube izinyanga eziyisithupha.
• i-melanoma ebulalayo, jovela umuthi ngemithambo yegazi izinsuku ezi-5 zilandelana amasonto ama-4, bese ungena kathathu ngesonto amasonto angama-48.
• i-follicular melanoma, jovela umuthi ngokunqamula kathathu ngesonto izinyanga ezifika kwezili-18.
• izinsumpa zangasese, jovela umuthi ngesisu kathathu ngesonto ngezinsuku ezihlukile zamaviki ama-3, khona-ke ukwelashwa kungaqhubeka kuze kube amasonto ayi-16.
• Kaposi’s sarcoma, jovela umuthi ngokuncipha noma nge-intramuscularly kathathu ngesonto amasonto ayi-16.

Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-interferon alfa-2b njengoba uqondisiwe. Ungawusebenzisi kakhulu lo muthi noma uwusebenzise kaningi noma isikhathi eside kunokuyalelwa ngudokotela wakho.

Udokotela wakho anganciphisa umthamo wakho uma uhlangabezana nemiphumela emibi yomuthi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa bese ubuza udokotela noma usokhemisi wakho uma unemibuzo mayelana nenani lemithi okufanele uyisebenzise.

Uzothola umthamo wakho wokuqala we-interferon alfa-2b ehhovisi likadokotela wakho. Ngemuva kwalokho, ungazijovela i-interferon alfa-2b ngokwakho noma umngane noma isihlobo sikunikeze imijovo. Ngaphambi kokusebenzisa i-interferon alfa-2b okokuqala ngqa, wena noma umuntu ozonikeza imijovo kufanele ufunde imininingwane yomenzi wesiguli esiza nayo. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani. Uma omunye umuntu ezokujovela lo muthi, qiniseka ukuthi uyazi ukuthi angazigwema kanjani izinaliti ngengozi.

Uma ujova lo muthi ngokunqamula, jovela i-interferon alfa-2b noma yikuphi endaweni yesisu sakho, ezingalweni ezingaphezulu, noma emathangeni akho, ngaphandle kwasezinkalweni zakho noma enkabeni yakho (esiswini). Ungafaki umuthi wakho esikhumbeni esivele sicasukile, silimele, sibomvu, sinegciwane noma sinezibazi.

Uma ujova lo muthi nge-intramuscularly, jovela i-interferon alfa-2b ezingalweni zakho, emathangeni, noma endaweni engaphandle yezinqa. Ungasebenzisi indawo efanayo izikhathi ezimbili zilandelana.Ungafaki umuthi wakho esikhumbeni esivele sicasukile, silimele, sibomvu, sinegciwane noma sinezibazi.

Uma ujova lo muthi ngaphakathi, jovela ngqo enkabeni yesisekelo sensumpa.

Ungalokothi usebenzise imijovo, izinaliti, noma izitsha ze-interferon alfa-2b. Lahla izinaliti nemijovo esetshenzisiwe esitsheni esingamelana nokubhoboza, bese ulahla izitsha zemithi ezisetshenzisiwe kudoti. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Ngaphambi kokusebenzisa i-interferon alfa-2b, bheka isixazululo esitsheni. Umuthi kufanele ucace futhi ungabi nezinhlayiya ezintantayo. Bheka i-vial ukuze uqiniseke ukuthi akukho kuvuza futhi uhlole usuku lokuphelelwa yisikhathi. Ungasebenzisi isixazululo uma siphelelwe yisikhathi, liguqubele, liqukethe izinhlayiya, noma lisemgodini ovuzayo.

Kufanele uxube kuphela isitsha esisodwa se-interferon alfa-2b ngasikhathi. Kungcono ukuxuba umuthi ngaphambi kokuhlela ukuwujova. Kodwa-ke, ungahlanganisa imishanguzo kusengaphambili, uyigcine esiqandisini, bese uyisebenzisa kungakapheli amahora angama-24. Qinisekisa ukukhipha imishanguzo esiqandisini bese uyivumela ukuthi ifike ekamelweni lokushisa ngaphambi kokuyijova.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-interferon alfa-2b futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo.

I-Interferon alfa-2b kwesinye isikhathi isetshenziswa ukwelapha igciwane le-hepatitis D (i-HDV; ukuvuvukala kwesibindi okubangelwa igciwane), i-basal cell carcinoma (uhlobo lomdlavuza wesikhumba), i-T-cell lymphomas (CTCL, uhlobo lomdlavuza wesikhumba) ), nomdlavuza wezinso. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-interferon alfa-2b,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji kumjovo we-interferon alfa-2b, eminye imithi ye-interferon alfa kufaka phakathi i-PEG-interferon alfa-2b (i-PEG-Intron) ne-PEG-interferon alfa-2a (Pegasys), noma imiphi eminye imithi, i-albumin, noma noma iziphi ezinye izithako zomjovo we-interferon alfa-2b. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: telbivudine (Tyzeka), theophylline (Elixophyllin, Theo-24, Theochron), noma i-zidovudine (Retrovir, eCombivir, eTrizivir). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma unesifo esibi sesibindi noma i-autoimmune hepatitis (isimo lapho amangqamuzana omzimba ahlasela isibindi). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi umjovo we-interferon alfa-2b.
• Tshela udokotela wakho noma usokhemisi uma ngabe uke wafakelwa isitho somzimba (ukuhlinzekwa ukufaka isitho emzimbeni) futhi uthatha imishanguzo yokuvikela amasosha akho omzimba. Phinda utshele udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SESEXWAYISO noma okunye kwalokhu okulandelayo: i-anemia (amaseli egazi abomvu aphansi) noma amaseli egazi amhlophe aphansi, izinkinga zokopha noma amahlule egazi kufaka phakathi i-pulmonary embolism ( I-PE; i-clot yegazi emaphashini), isifo samaphaphu njenge-pneumonia, i-pulmonary arterial hypertension (i-PAH; umfutho wegazi ophakeme emithanjeni ethwala igazi emaphashini, kubangele ukuphefumula, isiyezi nokukhathala), isifo esingapheliyo sokuphazamiseka kwamaphaphu (COPD; iqembu lezifo ezithinta amaphaphu nemigwaqo yomoya), noma izinkinga zamehlo.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-interferon alfa-2b, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola i-interferon alfa-2b.
• kufanele wazi ukuthi ungaba nezimpawu ezifana nomkhuhlane njengekhanda, ukujuluka, ubuhlungu bemisipha, nokukhathala ngemuva kokuthola umjovo wakho. Udokotela wakho angakutshela ukuthi uthathe i-acetaminophen (i-Tylenol), i-pain-the-counter kanye nemithi yomkhuhlane ukusiza ngalezi zimpawu. Khuluma nodokotela wakho uma lezi zimpawu kunzima ukuphatha noma ziba nzima.

Qaphela ukuthi uphuze uketshezi olwanele phakathi nokwelashwa kwakho kokuqala kwe-interferon alfa-2b.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa umthamo womjovo we-interferon alfa-2b, jovelela umthamo wakho olandelayo ngokushesha okukhulu lapho ukhumbula noma ukwazi ukuwunikeza. Ungasebenzisi umjovo we-interferon alfa-2b izinsuku ezimbili zilandelana. Musa ukujova umthamo ophindwe kabili ukwenzela umthamo ongabanjwanga. Shayela udokotela wakho uma uphuthelwa umthamo futhi unemibuzo mayelana nokuthi wenzeni.

Umjovo we-Interferon alfa-2b ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulimaza, ukopha, ubuhlungu, ukuba bomvu, ukuvuvukala, noma ukucasuka endaweni owafaka kuyo i-interferon alfa-2b
• ubuhlungu bemisipha
• shintsha emandleni okunambitha
• ukulahleka kwezinwele
• isiyezi
• umlomo owomile
• izinkinga zokuhlushwa
• ukuzwa kubanda noma kushisa
• izinguquko zesisindo
• izinguquko zesikhumba

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma yiziphi noma lezo ezibalwe eziXwayisweni EZIBALULEKILE noma ezigabeni EZIKHETHEKILE, Fonela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukuxebuka kwesikhumba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo
• izinguquko embonweni
• ubuhlungu besisu, ubumnene noma ukuvuvukala
• ukuphuzi kwesikhumba noma kwamehlo
• ukukhathala ngokweqile
• ukudideka
• isifo sohudo
• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukuhlanza
• ukuhlungu obusemhlane
• ukulahlekelwa ukwazi
• ukuba ndikindiki, ukushiswa noma ukuncinza ezandleni noma ezinyaweni

Umjovo we-Interferon alfa-2b ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine esiqandisini, kodwa ungayifaki iqhwa. Uma usuxubene, yisebenzise ngokushesha. Ingagcinwa esiqandisini amahora angafika kwangu-24 ngemuva kokuxubeka. Lahla noma imuphi umuthi osuphelelwe yisikhathi noma ongasadingeki. Khuluma nosokhemisi wakho ngokulahlwa okufanele kwemithi yakho.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Intron A^®