I-Lamotrigine

-Delile

• Ngaphambi kokuthatha i-lamotrigine,
• I-Lamotrigine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezichazwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

[Kuthunyelwe ngo-03/31/2021]

ISIHLOKO: Ucwaningo lukhombisa ukwanda kwengcuphe yezinkinga zesigqi senhliziyo ngokubanjwa kanye nemithi yezempilo yengqondo i-lamotrigine (Lamictal) ezigulini ezinesifo senhliziyo

Isithameli: Isiguli, Ochwepheshe Bezempilo, Ikhemisi

INKINGA: Ukubuyekezwa kokutholakele kocwaningo kwe-U.S. Food and Drug Administration (FDA) kukhombise ubungozi obungahle bube khona bezinkinga zesigqi senhliziyo, ezibizwa ngama-arrhythmias, ezigulini ezinesifo senhliziyo ezithatha umuthi wokuquleka nowempilo yezengqondo i-lamotrigine (Lamictal). Sifuna ukuhlola ukuthi ngabe eminye imithi esesigabeni esifanayo semithi inemiphumela efanayo yini enhliziyweni futhi idinga izifundo zokuphepha kuyo nayo. Sizokwazisa umphakathi uma imininingwane eyengeziwe evela kulezi zifundo itholakala. I-FDA idinga lezi zifundo, ezibizwa nge-in vitro studies, ukuze ziqhubeke nokuphenya ngemiphumela kaLamictal enhliziyweni ngemuva kokuthola imibiko yokutholakala okungavamile kwe-electrocardiographic (ECG) nezinye izinkinga ezinkulu. Kwezinye izimo, izinkinga ezibandakanya ubuhlungu besifuba, ukulahlekelwa ukwazi nokuboshwa kwenhliziyo kwenzeka. Izifundo ze-in vitro yizifundo ezenziwa kumashubhu wokuhlola noma ezitsheni ze-petri hhayi kubantu noma ezilwaneni. Siqale ngokungeza imininingwane ngale ngozi kwi-lamotrigine enquma imininingwane kanye neMihlahlandlela Yezokwelapha ngo-Okthoba 2020, esiyivuselele.

ISENDLALELO: ILamotrigine isetshenziswa yodwa noma neminye imithi yokwelapha ukuquleka ezigulini ezineminyaka emibili nangaphezulu. Ingasetshenziswa futhi njengokwelashwa kwesondlo ezigulini ezinesimo sempilo yengqondo isifo se-bipolar ukusiza ukubambezela ukuvela kweziqephu zemizwa ezifana nokudana, i-mania, noma i-hypomania. ILamotrigine ivunyelwe futhi isemakethe isikhathi esingaphezu kweminyaka engama-25 futhi itholakala ngaphansi kwegama lomkhiqizo iLamictal nanjengemithi ejwayelekile.

UKUNCOMA:

Ochwepheshe Bokunakekelwa Kwezempilo

• Hlola ukuthi izinzuzo ezingaba khona ze-lamotrigine zidlula ingozi engaba khona ye-arrhythmias yesiguli ngasinye.
• Ukuhlolwa kwelabhorethri okwenziwe ekugxilweni okuphathelene nokwelashwa kukhombisile ukuthi i-lamotrigine ingakhuphula ubungozi be-arrhythmias enkulu, engabeka impilo ezigulini ezinenkinga yenhliziyo ehlelekile noma esebenzayo. Izinkinga zenhliziyo ezibalulekile ezakhiwayo nezisebenza kahle zifaka ukwehluleka kwenhliziyo, isifo senhliziyo se-valvular, isifo senhliziyo esizelwe, isifo sohlelo lokuqhuba, ama-arrhythmias e-ventricular, ama-channelopathies enhliziyo afana ne-Brugada syndrome, isifo senhliziyo esibalulekile emtholampilo, noma izici eziningi zobungozi besifo semithambo yenhliziyo.
• Ubungozi be-arrhythmias bungakhuphuka buqhubeke uma busetshenziswa ngokuhlangana neminye imithi evimba iziteshi ze-sodium enhliziyweni. Abanye abavimba iziteshi ze-sodium abavunyelwe isithuthwane, ukuphazamiseka kwengqondo okuguquguqukayo, nezinye izinkomba akufanele kubhekwe njengezindlela eziphephe kunazo zonke ze-lamotrigine uma kungekho eminye imininingwane.

Iziguli, Abazali, kanye Nabanakekeli

• Ungayeki ukuphuza umuthi wakho ngaphandle kokuqala ukhulume nalowo obhalele yena ngoba ukumisa i-lamotrigine kungaholela ekuqulekeni okungalawuleki, noma ezinkingeni zempilo yengqondo ezintsha noma ezimbi kakhulu.
• Xhumana nochwepheshe wezokunakekelwa kwezempilo ngokushesha noma uye egumbini lezimo eziphuthumayo uma uhlangabezana nokushaya kwenhliziyo okungavamile noma isigqi esingajwayelekile, noma izimpawu ezinjengokushaya kwenhliziyo okugijimayo, ukweqa noma ukushaya kwenhliziyo, ukuphefumula okuncane, isiyezi, noma ukuquleka.

Ukuthola eminye imininingwane vakashela iwebhusayithi ye-FDA ku: http://www.fda.gov/Safety/MedWatch/SafetyInformation naku-http: //www.fda.gov/Drugs/DrugSafety.

I-Lamotrigine ingadala ukuqubuka, kufaka phakathi ukuqubuka okukhulu okungadinga ukwelashwa esibhedlela noma kubangele ukukhubazeka unomphela noma ukufa. Tshela udokotela wakho uma uthatha i-valproic acid (i-Depakene) noma i-divalproex (i-Depakote) ngoba ukuthatha le mithi nge-lamotrigine kungakhuphula ingozi yokuba nokuqubuka okukhulu. Phinda utshele udokotela wakho uma wake waqubuka ngemuva kokuthatha i-lamotrigine noma omunye umuthi wesifo sokuwa noma uma uxabana nanoma imiphi imithi yesifo sokuwa.

Udokotela wakho uzokuqala ngomthamo ophansi we-lamotrigine futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo emavikini ayi-1 kuya kwangu-2. Ungase ube namathuba amaningi okuthuthukisa ukuqubuka okukhulu uma uthatha umthamo ophakeme wokuqala noma ukwandisa umthamo wakho ngokushesha kunokuba udokotela wakho ekutshela ukuthi kufanele. Imithamo yakho yokuqala yemithi ingafakwa kukhithi yokuqalisa ezokukhombisa ngokusobala inani elifanele lemithi ozolithatha usuku ngalunye phakathi kwamaviki amahlanu okuqala wokwelashwa kwakho. Lokhu kuzokusiza ukuthi ulandele imiyalo kadokotela wakho njengoba umthamo wakho wanda kancane. Qinisekisa ukuthatha i-lamotrigine njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Ukuqubuka okukhulu kuvame ukukhula phakathi nokwelashwa kwamasonto amabili kuya kwayisishiyagalombili nge-lamotrigine, kepha kungakhula nganoma yisiphi isikhathi lapho welashwa. Uma uba nezimpawu ezilandelayo ngenkathi uthatha i-lamotrigine, shayela udokotela wakho ngokushesha: ukuqubuka; ukushwabana noma ukuxebuka kwesikhumba; isifuba; ukulunywa; noma izilonda ezibuhlungu emlonyeni wakho noma eduze kwamehlo akho.

Khuluma nodokotela wakho ngezingozi zokuthatha i-lamotrigine noma ngokunikeza i-lamotrigine enganeni yakho. Izingane ezineminyaka engu-2-17 ubudala ezithatha i-lamotrigine zinamathuba amaningi okuba nokuqubuka okukhulu kunabantu abadala abathatha umuthi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-lamotrigine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Amaphilisi e-Lamotrigine anwetshiwe (asebenza isikhathi eside) asetshenziswa neminye imithi yokwelapha izinhlobo ezithile zokubanjwa kweziguli ezinesifo sokuwa. Zonke izinhlobo zamaphilisi e-lamotrigine (amaphilisi, amaphilisi ahlukaniswa ngomlomo, namathebulethi angahlafunwayo) ngaphandle kwamaphilisi akhishwa enwetshiwe asetshenziswa yedwa noma ngeminye imithi yokwelapha ukuquleka kubantu abanesithuthwane noma i-Lennox-Gastaut syndrome (isifo esidala ukuquleka futhi kuvame ukudala ukubambezeleka kwentuthuko). Zonke izinhlobo zamaphilisi we-lamotrigine ngaphandle kwamaphilisi akhululiwe asetshenziselwa ukwandisa isikhathi phakathi kweziqephu zokucindezeleka, i-mania (imizwa evuthayo noma ejabule ngokweqile), nezinye izimo ezingavamile ezigulini ezine-bipolar I disorder (isifo sokudangala komuntu) isifo esibangela iziqephu zokucindezeleka, iziqephu ze-mania, nezinye izimo ezingavamile). ILamotrigine ayikhonjiswanga ukuthi iyasebenza lapho abantu bezwa iziqephu zangempela zokucindezeleka noma i-mania, ngakho-ke eminye imithi kufanele isetshenziselwe ukusiza abantu ukuthi balulame kulezi ziqephu. ILamotrigine isekilasini lemithi ebizwa ngama-anticonvulsants. Isebenza ngokunciphisa umsebenzi kagesi ongajwayelekile ebuchosheni.

ILamotrigine iza njengethebhulethi, ithebhulethi ekhishwa isikhathi eside, ithebhulethi eyahlakazeka ngomlomo (iyancibilika emlonyeni futhi ingagwinywa ngaphandle kwamanzi), kanye nethebhulethi ehlafunwayo (engahlafunwa noma ichithwe ngoketshezi) ithebhulethi ongayithatha ngomlomo noma ngaphandle ukudla. Amaphilisi akhishwa isikhathi eside athathwa kanye ngosuku. Amathebulethi, amaphilisi ahlukaniswa ngomlomo, namathebulethi ahlafunwayo ngokuvamile athathwa kanye noma kabili ngosuku, kodwa angaphuzwa kanye njalo ngosuku lokuqala lokwelashwa. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi.

Kuneminye imithi enamagama afana negama lomkhiqizo le-lamotrigine. Kufanele uqiniseke ukuthi uthola i-lamotrigine hhayi umuthi ofanayo njalo lapho ugcwalisa incwadi kadokotela. Qiniseka ukuthi incwadi kadokotela akunikeza yona icacile futhi ifundeka kalula. Khuluma nosokhemisi wakho ukuze uqiniseke ukuthi unikezwa i-lamotrigine. Ngemuva kokuthola umuthi wakho, qhathanisa amaphilisi nezithombe ezikushidi lemininingwane yesiguli lomkhiqizi. Uma ucabanga ukuthi unikezwe umuthi ongafanele, khuluma nosokhemisi wakho. Ungathathi noma imuphi umuthi ngaphandle uma uqinisekile ukuthi ngumuthi owunikwe udokotela wakho.

Gwinya amathebulethi namaphilisi akhululiwe enwetshiwe ngokuphelele; ungawahlukanisi, ungawahlafune noma uwagxoze.

Uma uthatha amaphilisi ahlafunwayo angahlakazeka, ungawagwinya ephelele, uwahlafune, noma uwaqede uketshezi. Uma uhlafuna amaphilisi, phuza inani elincane lamanzi noma ijusi yezithelo ehlanjululwe ngemuva kwalokho ukugeza umuthi. Ukwehlisa amaphilisi kuketshezi, faka isipuni 1 (5 ml) samanzi noma ijusi yezithelo ehlanjululwe engilazini. Beka ithebhulethi koketshezi bese ulinda iminithi elingu-1 ukuyivumela incibilike. Bese ugijimisa uketshezi bese uliphuza lonke ngokushesha. Ungazami ukwehlukanisa ithebhulethi eyodwa ezosetshenziselwa umthamo ongaphezu kowodwa.

Ukuthatha ithebhulethi ehlakazeka ngomlomo, ibeke olimini lwakho bese uyihambisa emlonyeni wakho. Linda isikhashana ukuthi ithebhulethi incibilike, bese uyigwinya ngamanzi noma ngaphandle kwawo.

Uma umuthi wakho ufika ku-blisterpack, hlola i-blisterpack ngaphambi kokuthatha umthamo wakho wokuqala. Ungasebenzisi noma imuphi umuthi osuka ephaketheni uma kukhona amabhamuza adabukile, aphukile, noma aqukethe amaphilisi.

Uma ubuthatha omunye umuthi ukwelapha ukuquleka futhi ushintshela ku-lamotrigine, udokotela wakho uzokwehlisa kancane kancane umthamo wakho womunye umuthi futhi akhuphule kancane umthamo wakho we-lamotrigine. Landela lezi zinkombandlela ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo mayelana nokuthi ungakanani umuthi ngamunye okufanele uwuthathe.

ILamotrigine ingalawula isimo sakho, kepha ngeke iselaphe. Kungathatha amasonto ambalwa ukuthi uzwe inzuzo ephelele ye-lamotrigine. Qhubeka uphuze i-lamotrigine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-lamotrigine ngaphandle kokukhuluma nodokotela wakho, noma ngabe uhlangabezana nemiphumela emibi njengokushintsha okungavamile kokuziphatha noma kwemizwelo. Udokotela wakho mhlawumbe uzokwehlisa umthamo wakho kancane kancane. Uma ngokungazelelwe uyeka ukuthatha i-lamotrigine, ungahle ube nokuquleka. Uma uyeka ukuthatha i-lamotrigine nganoma yisiphi isizathu, ungaqali ukuyithatha futhi ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lamotrigine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-lamotrigine, noma imiphi eminye imithi. noma yiziphi izithako zohlobo lwamaphilisi we-lamotrigine ozobe uwaphuza. Buza udokotela wakho noma usokhemisi noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SEXWAYISO kanye ne-atazanavir ene-ritonavir (Reyataz neNorvir); i-lopinavir ne-ritonavir (Kaletra); i-methotrexate (Rasuvo, Trexall, Trexup); eminye imithi yokwelashwa okufana ne-carbamazepine (Epitol, Tegretol, abanye), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin, Phenytek), ne-primidone (Mysoline); i-pyrimethamine (iDaraprim); i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, i-Rifater); ne-trimethoprim (Primsol, eBactrim, Septra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma usebenzisa imishanguzo yabesifazane yamahomoni njengezindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, imijovo, okufakelwa, noma amadivayisi we-intrauterine), noma i-hormone replacement therapy (HRT). Khuluma nodokotela wakho ngaphambi kokuba uqale noma uyeke ukuthatha noma iyiphi yale mithi ngenkathi uthatha i-lamotrigine. Uma uthatha umuthi wabesifazane we-hormonal, tshela udokotela wakho uma uphuma igazi phakathi kwezikhathi ezilindelekile zokuya esikhathini.
• Tshela udokotela wakho uma uke waba nesifo sokuzilimaza (isimo lapho umzimba uhlasela izitho zawo uqobo, kubangele ukuvuvukala nokulahleka kokusebenza) njenge-lupus (isimo lapho umzimba uhlasela khona izitho eziningi ezahlukahlukene ezibanga izimpawu ezahlukahlukene) , ukuphazamiseka kwegazi, ezinye izimo zempilo yengqondo, noma isifo sezinso noma sesibindi, noma i-ascites (ukuvuvukala kwesisu okubangelwa yisifo sesibindi).
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-lamotrigine, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Uma uncelisa ibele ngesikhathi sokwelashwa kwakho nge-lamotrigine, ingane yakho ingathola i-lamotrigine ebisi lwebele. Bhekisisa ingane yakho ubuthongo obungajwayelekile, ukuphefumula okuphazamisekile, noma ukuncela kabi.
• kufanele wazi ukuthi lo muthi ungakwenza ukozele noma ube nesiyezi. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile futhi ungazibulala (ucabange ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo) ngenkathi uthatha i-lamotrigine ekwelashweni kwesifo sokuwa, ukugula kwengqondo, noma ezinye izimo. Inani elincane labantu abadala nezingane ezineminyaka engu-5 nangaphezulu (cishe umuntu oyedwa kwabangu-500) abathathe ama-anticonvulsants afana ne-lamotrigine ukwelapha izimo ezahlukahlukene phakathi kwezifundo zokwelashwa baba nokuzibulala ngesikhathi belashwa. Abanye balaba bantu bahlakulela imicabango yokuzibulala nokuziphatha kungakapheli isonto elilodwa beqale ukuthatha umuthi. Kunobungozi bokuthi ungathola ushintsho empilweni yakho yengqondo uma uthatha umuthi we-anticonvulsant ofana ne-lamotrigine, kepha kungahle kube nengozi yokuthi uzohlangabezana nezinguquko empilweni yakho yengqondo uma isimo sakho singelashwa. Wena nodokotela wakho nizonquma ukuthi izingozi zokuthatha umuthi we-anticonvulsant zinkulu yini kunezingozi zokungawuthathi umuthi. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukwethuka; ukuphazamiseka noma ukungahlaliseki; ukucasuka okusha noma okuya kuba kubi, ukukhathazeka, noma ukucindezeleka; ukwenza izinkanuko eziyingozi; ubunzima bokulala noma ukulala; ulaka, intukuthelo, noma ukuziphatha okunodlame; i-mania (i-frenzied, imood ejabule ngokungavamile); ukukhuluma noma ukucabanga ngokufuna ukuzilimaza noma ukuqeda impilo yakho; ukuhoxa kubangani nomndeni; ukukhathazeka ngokufa nokufa; ukuphana ngezinto eziyigugu; noma olunye uguquko olungajwayelekile ekuziphatheni noma emoyeni. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Lamotrigine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulahlekelwa ibhalansi noma ukuxhumanisa
• ukubona kabili
• ukungaboni kahle
• ukunyakaza okungalawuleki kwamehlo
• ubunzima bokucabanga noma ukugxila
• kunzima ukukhuluma
• ikhanda
• ukozela
• isiyezi
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• isilungulela
• isicanucanu
• ukuhlanza
• umlomo owomile
• isisu, iqolo, noma ubuhlungu bamalunga
• izikhathi ezingaphuthi noma ezibuhlungu zokuya esikhathini
• ukuvuvukala, ukulunywa, noma ukucasuka kwesitho sangasese sowesifazane
• ukuzamazama okungalawuleki kwengxenye yomzimba

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezichazwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, namehlo, ubunzima bokugwinya noma bokuphefumula, ukubhonga
• ukuquleka okwenzeka kaningi, kuhlala isikhathi eside, noma kwehlukile kunokuquleka owawunakho esikhathini esedlule
• ikhanda, umkhuhlane, isicanucanu, ukuhlanza, intamo eqinile, ukuzwela ekukhanyeni, ukugodola, ukudideka, ubuhlungu bemisipha, ukozela
• ukopha okungajwayelekile noma ukulinyazwa
• imfiva, ukuqubuka, ukuvuvukala kwama-lymph node, ukuphuzi kwesikhumba noma kwamehlo, ubuhlungu besisu, ukuchama okubuhlungu noma okunegazi, ubuhlungu besifuba, ubuthakathaka bemisipha noma ubuhlungu, ukopha okungavamile noma ukulimaza, ukuquleka, ukuhamba kanzima, ubunzima bokubona noma ezinye izinkinga zombono
• umphimbo obuhlungu, umkhuhlane, ukubanda, ukukhwehlela, ukuphefumula kanzima, ubuhlungu bendlebe, iso elibomvana, ukuchama kaningi noma okubuhlungu, noma ezinye izimpawu zokutheleleka

I-Lamotrigine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa, kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukulahlekelwa ibhalansi noma ukuxhumanisa
• ukunyakaza okungalawuleki kwamehlo
• ukubona kabili
• ukuquleka okwengeziwe
• ukushaya kwenhliziyo okungajwayelekile
• ukulahlekelwa ukwazi
• ikhoma

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yakho ku-lamotrigine.

Ngaphambi kokwenza noma yiluphi uvivinyo lwe-laboratory, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-lamotrigine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Lamictal^®
• I-Lamictal^® CD
• I-Lamictal^® ODT
• I-Lamictal^® XR