I-Colchicine (Colchis): iyini, yenzelwe ini nokuthi isetshenziswa kanjani

-Delile

• Yenzelwe ini
• Isetshenziswa kanjani
• 1. Ukulwa namantombazane
• 2. Isifo sikaPeyronie
• I-Colchicine yokwelashwa kwe-COVID-19
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

IColchicine ngumuthi olwa nokuvuvukala osetshenziselwa ukwelapha nokuvikela ukuhlaselwa yi-gout. Ngaphezu kwalokho, ingasetshenziselwa ukwelapha amacala we-gout engapheli, imfiva yomndeni yaseMedithera noma lapho usebenzisa izidakamizwa ezehlisa i-uric acid.

Lo muthi ungathengwa ezikhemisi, ngohlobo olujwayelekile noma ngegama lokuhweba iColchis, ngamaphakethe amaphilisi angama-20 noma angama-30, lapho kwethulwa incwadi kadokotela.

Yenzelwe ini

IColchicine umuthi osetshenziselwa ukwelapha ukuhlaselwa yi-gout acute nokuvikela ukuhlaselwa okuqatha kubantu abane-gouty arthritis engapheli.

Thola ukuthi yini i-gout, ukuthi yini ebangela nezimpawu ezingavela.

Ngaphezu kwalokho, ukwelashwa ngalo muthi kungakhonjiswa kwisifo sikaPeyronie, iMedithera Yomndeni waseMedithera futhi ezimweni ze-scleroderma, i-polyarthritis ehlotshaniswa ne-sarcoidosis ne-psoriasis.

Isetshenziswa kanjani

Uhlobo lokusetshenziswa kwe-colchicine luyehluka ngokuya ngesibonakaliso salo, noma kunjalo, noma kunjalo kubalulekile ukugwema ukufaka i-colchicine kanye nejusi lamagilebhisi, ngoba lesi sithelo singavimbela ukuqedwa komuthi, kwandise ubungozi bezinkinga kanye nemiphumela ebambekayo.

1. Ukulwa namantombazane

Ukuze kuvinjelwe ukuhlaselwa yi-gout, umthamo ophakanyisiwe yi-1 tablet ka-0.5 mg, kanye kuya kathathu ngosuku, ngomlomo. Iziguli ezihlinzwayo kufanele zithathe ithebhulethi elilodwa kathathu ngosuku, njalo emahoreni ayisishiyagalombili, ngomlomo, ezinsukwini ezintathu ngaphambi kwezinsuku ezi-3 ngemuva kokuhlinzwa.

Ukuze kutholakale ukuhlaselwa okunamandla kwe-gout, umthamo wokuqala kufanele ube ngu-0.5 mg kuye ku-1.5 mg kulandelwe ithebhulethi eli-1 ngezikhathi ezi-1, noma amahora amabili, kuze kuvele ukukhululeka kobuhlungu noma isicanucanu, ukuhlanza noma uhudo. Umthamo akufanele neze wenyuswe ngaphandle kokuqondiswa udokotela, noma ngabe izimpawu zingathuthuki.

Iziguli ezingalapheki zingaqhubeka nokwelashwa ngomthamo wesondlo wamaphilisi ama-2 ngosuku, njalo emahoreni ayi-12, kuze kufike ezinyangeni ezintathu, ngokokubona kukadokotela.

Umthamo omkhulu ofinyelelwe akufanele udlule u-7 mg nsuku zonke.

2. Isifo sikaPeyronie

Ukwelashwa kufanele kuqalwe ngo-0.5 mg kuye ku-1.0 mg nsuku zonke, kuhlinzekwe ngemithamo eyodwa kuya kwemibili, engakhuphuka ifike ku-2 mg ngosuku, ilawulwa ngemithamo emibili kuya kwemithathu.

I-Colchicine yokwelashwa kwe-COVID-19

Ngokombiko wokuqala okhishwe yiMontreal Heart Institute ^[1], i-colchicine ikhombise imiphumela emihle ekwelapheni iziguli ezine-COVID-19. Ngokusho kwabacwaningi, lo muthi ubonakala wehlisa izinga lokulaliswa nokufa kwabantu esibhedlela, lapho ukwelashwa kuqala ngaphambi nje kokuxilongwa.

Kodwa-ke, kusadingeka ukuthi yonke imiphumela yalolu cwaningo yaziwe futhi ihlaziywe ngumphakathi wesayensi, futhi kunconywa ukuthi kuqhutshekwe nophenyo ngalo muthi, ikakhulukazi ngoba kungumuthi ongadala imiphumela emibi lapho hhayi esetshenzisiwe kumthamo.lungile nangaphansi kokuqondisa kukadokotela.

Ngubani ongafanele asebenzise

Leli khambi akufanele lisetshenziswe kubantu abanezinto ezingezwani nezinto ezithile kunoma yiziphi izinto ezikhona kwifomula, abantu abenza i-dialysis noma abantu abanezifo ezinzima zesisu, i-hematological, isibindi, izinso noma izifo zenhliziyo.

Ngaphezu kwalokho, akufanele futhi isetshenziselwe izingane, abesifazane abakhulelwe noma abesifazane abancelisayo.

Imiphumela emibi engaba khona

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwalo muthi ukuhlanza, isicanucanu, ukukhathala, ikhanda elibuhlungu, i-gout, amajaqamba, ubuhlungu besisu nobuhlungu be-larynx nepharynx. Omunye umphumela obaluleke kakhulu uhudo, okuthi, uma luvela, kufanele lubikwe ngokushesha kudokotela, njengoba kukhombisa ukuthi ukwelashwa kufanele kumiswe.

Ngaphezu kwalokho, yize kungavamile, ukulahleka kwezinwele, ukudangala komgogodla, i-dermatitis, izinguquko ekucinaneni nasezibindini, ukusabela okweqile, ukwanda kwe-creatine phosphokinase, ukungabekezelelani kwe-lactose, ubuhlungu bemisipha, inani elincishisiwe lesidoda, onsomi, ukubhujiswa kwamaseli emisipha kanye ne-neuromuscular enobuthi isifo.