ILeptin: yini, kungani ingahle ibe phezulu nokuthi yini okufanele uyenze

-Delile

• Amanani ajwayelekile we-leptin
• Uwahlola kanjani amazinga e-leptin
• Kusho ukuthini ukuba ne-leptin ephezulu
• Ubudlelwano phakathi kwe-leptin nokulahleka kwesisindo
• Okufanele ukwenze lapho i-leptin iphakeme
• 1. Ukwehla kwesisindo kancane
• 2. Gwema ukudla okubanga ukumelana ne-leptin
• 3. Landela ukudla okunempilo
• 4. Yenza umsebenzi womzimba
• 5. Ulale kahle
• Uyini umehluko phakathi kwe-leptin ne-ghrelin

ILeptin yihomoni ekhiqizwa ngamangqamuzana amafutha, asebenza ngqo ebuchosheni futhi imisebenzi yayo eyinhloko ukulawula ukudla, ukunciphisa ukudla nokulawula ukusetshenziswa kwamandla, okuvumela isisindo somzimba ukuba sigcinwe.

Ezimweni ezijwayelekile, lapho umzimba unamaseli amaningi anonile, kukhona ukukhuphuka kokukhiqizwa kwe-leptin, okuthumela ebuchosheni umyalezo wokuthi kuyadingeka ukunciphisa ukudla okudliwayo ukuze kulawulwe isisindo. Ngakho-ke, lapho i-leptin yanda, kuncipha ukudla futhi umuntu agcine esedla kancane.

Kodwa-ke, kwabanye abantu isenzo se-leptin singaguqulwa, okusho ukuthi, noma ngabe kunamafutha amaningi anqwabelene, umzimba awuphenduli ku-leptin ngakho-ke, awukho umthethonqubo wokudla futhi abantu basenokuningi yesifiso sokudla futhi kwenze kube nzima, okwenza kube nzima ukwehlisa isisindo.

Ngakho-ke, ukwazi ukuthi ungasithuthukisa kanjani isenzo se-leptin kungaba isu elihle lokuzuza ukwehla kwesisindo kuze kube phakade naphakade.

Amanani ajwayelekile we-leptin

Amanani ajwayelekile we-leptin ancike ocansini, inkomba yomzimba nobudala:

• Abesifazane abane-BMI ka-18 kuya ku-25: 4.7 kuya ku-23.7 ng / mL;
• Abesifazane abane-BMI enkulu kuno-30: 8.0 kuye ku-38.9 ng / mL;
• Amadoda ane-BMI ye-18 kuye ku-25: 0.3 kuya ku-13.4 ng / mL;
• Abesilisa abane-BMI enkulu kuno-30: inani elijwayelekile leptin lingu-1.8 kuye ku-19.9 ng / mL;
• Izingane kanye nabantu abasha abaneminyaka engu-5 kuya kwengu-9 ubudala: 0.6 kuya ku-16.8 ng / mL;
• Izingane kanye nabantu abasha abaneminyaka engu-10 kuya ku-13: 1.4 kuya ku-16.5 ng / mL;
• Izingane kanye nabantu abasha abaneminyaka engu-14 kuya kwengu-17: 0.6 kuya ku-24.9 ng / mL.

Amanani we-Leptin nawo angahluka ngokuya ngesimo sempilo futhi angakhuphuka ngenxa yethonya lezinto ezivuthayo noma ama-hormone afana ne-insulin noma i-cortisol, isibonelo.

Ezinye izinto, ngakolunye uhlangothi, zinganciphisa amazinga e-leptin, njengokunciphisa umzimba, ukuzila ukudla isikhathi eside, ukubhema, noma ithonya lamahomoni afana ne-thyroid noma i-hormone yokukhula.

Uwahlola kanjani amazinga e-leptin

Amazinga e-Leptin ahlolwa ngokuhlolwa okumele ku-odolwe ngudokotela noma uchwepheshe wezokudla futhi kwenziwa ngokuqoqwa kwegazi.

Ukwenza isivivinyo, kufanele uzile ukudla amahora ayi-12, noma kunjalo, amanye amalabhorethri, ngokuya ngendlela esetshenzisiwe, cela ukuzila ukudla kwamahora ama-4 kuphela. Ngakho-ke, izincomo zokuzila kufanele zihlolwe elabhorethri ngaphambi kokwenza isivivinyo.

Kusho ukuthini ukuba ne-leptin ephezulu

I-leptin ephezulu, eyaziwa ngokwesayensi njenge-hyperleptinemia, ivame ukwenzeka ezimweni zokukhuluphala, ngoba njengoba kunamaseli amaningi anonile, ukukhiqizwa kwe-leptin kuyanda njalo, uma lokhu kwenzeka, ubuchopho buqala ukubheka i-leptin ephezulu njengokujwayelekile futhi indlala yayo elawulayo ayisasebenzi . Lesi simo saziwa ngokuthi ukumelana ne-leptin.

Ngaphezu kwalokho, ukungeniswa kokudla njengokucutshungulwa, ukucutshungulwa, imikhiqizo ekheniwe, ecebile ngamafutha noma ushukela, ngokwesibonelo, kungadala ukuvuvukala kumaseli, nakho okunomthelela ekumelaneni ne-leptin.

Lokhu kumelana kuholela ekwandeni kwendlala nokunciphisa ukushiswa kwamafutha emzimbeni, okwenza kube nzima ukunciphisa isisindo.

Ubudlelwano phakathi kwe-leptin nokulahleka kwesisindo

ILeptin ibizwa nge-hormone yokusutha, ngoba le hormone, uma ikhiqizwa ngamangqamuzana anamafutha nobuchopho iyaluqonda isignali ye-leptin yokwehlisa isifiso sokudla nokwandisa ukushisa kwamafutha, ukwehla kwesisindo kwenzeka kalula.

Kodwa-ke, lapho ukukhiqizwa kwe-leptin okuyihaba kwenzeka, ubuchopho buyehluleka ukuqonda isignali yokuyeka ukudla bese benza ngendlela ehlukile, kwandisa indlala, okwenza ukwehla kwesisindo kube nzima noma kukhuphuke isisindo somzimba, lokhu kuyindlela ephathekayo yokumelana ne-leptin.

Ezinye izifundo zesayensi zenziwe ukuzama ukuthuthukisa ukuxhumana phakathi kwamangqamuzana akhiqiza i-leptin nobuchopho ukuze i-leptin isetshenziswe kahle, kuvuna ukulahleka kwesisindo kwabantu abakhuluphele. Kodwa-ke, ezinye izifundo zisadingeka.

Okufanele ukwenze lapho i-leptin iphakeme

Ezinye izindlela ezilula zokwehlisa nokujwayelekile amazinga aphezulu e-leptin nokunciphisa ukumelana nale hormone, okufaka isandla ekwehliseni isisindo yilezi:

1. Ukwehla kwesisindo kancane

Lapho kunokuncipha okungazelelwe kwesisindo, amazinga e-leptin nawo ancipha ngokushesha futhi nengqondo iyaqonda ukuthi ihamba esigabeni sokuvinjelwa kokudla, futhi ngaleyo ndlela ivuse inkanuko yokudla. Lesi ngesinye sezizathu eziyinhloko zokuyeka ukudla, njengoba kukhona ukwanda kwendlala, nobunzima obukhulu bokugcina isisindo esilahlekile. Ngakho-ke, lapho wehlisa isisindo kancane, amazinga e-leptin ancipha kancane kancane ngaphezu kokusebenza kahle nokulawulwa kwesifiso kulula.

2. Gwema ukudla okubanga ukumelana ne-leptin

Okunye ukudla okufana noshukela, amaswidi, ukudla okunamafutha kakhulu, imikhiqizo ekheniwe nocutshunguliwe kungadala ukuvuvukala kumaseli futhi kuholele ekumelaneni ne-leptin. Ngaphezu kwalokho, lokhu kudla kwandisa ingozi yokuba nesifo sikashukela, isifo senhliziyo nokukhuluphala.

3. Landela ukudla okunempilo

Lapho udla ukudla okunempilo, umzimba uthola zonke izakhi zomzimba ezidingekayo, okudala ukuthambekela kwemvelo okwehlise isifiso sokudla. Nakhu ukuthi ungadla kanjani ukudla okunempilo.

4. Yenza umsebenzi womzimba

Imisebenzi yomzimba isiza ukunciphisa ukumelana ne-leptin, isiza ekusebenzeni kwayo ukulawula inkanuko nokwandisa ukushiswa kwamafutha. Ukwehlisa isisindo okunempilo, kunconywa ukuthi uhambe imizuzu engama-20 kuye kwengama-30 nsuku zonke, kanye nokudla okunempilo. Kubalulekile ukwenza ukuhlolwa kwezokwelapha ngaphambi kokuqala ukuvivinya umzimba futhi, ikakhulukazi kubantu abakhuluphele, umuntu kufanele ahambisane nomfundisi wezempilo ukuze agweme imizamo eyeqisayo nobungozi bokulimala okungadikibalisa ukwehla kwesisindo.

5. Ulale kahle

Olunye ucwaningo lubonisa ukuthi ukungalali amahora angu-8 kuya kwangu-9 okulala kunganciphisa amazinga e-leptin futhi kubangele ukwanda kwesifiso sokudla. Ngaphezu kwalokho, ukukhathala kanye nengcindezi yokungalali ngokwanele, kwandisa amazinga e-hormone i-cortisol, okwenza ukuncipha kwesisindo kube nzima.

Bona kuvidiyo engezansi ukuthi i-leptin ingalawulwa kanjani ngesikhathi sokulala ukuze yehlise isisindo.

Olunye ucwaningo lwesayensi ngama-leptin supplements akhombisa ukuthi izakhamzimba ezahlukahlukene zesengezo zisiza ukuthuthukisa ukuzwela kwe-leptin futhi zikhuthaze ukusutha. Kodwa-ke, kusadingeka izifundo ukuze kufakazelwe ukusebenza kwalezi zithasiselo. Bheka izithasiselo ezihamba phambili ukukusiza ulahlekelwe isisindo.

Ngokunjalo, izifundo ngokuzila ukudla ngezikhathi ezithile kumagundane zikhombisile ukwehla kwamazinga e-leptin, noma kunjalo, ukusebenza kahle kokuzila ukudla ngezikhathi ezithile kusaphikisana nabantu, futhi kudingeka izifundo ezengeziwe.

Uyini umehluko phakathi kwe-leptin ne-ghrelin

Kokubili i-leptin ne-ghrelin ngamahomoni enza ngokulawula isifiso sokudla. Kodwa-ke, i-ghrelin, ngokungafani ne-leptin, inyusa ukudla.

IGhrelin ikhiqizwa ngamangqamuzana esisu futhi isebenza ngqo ebuchosheni, ukukhiqizwa kwayo kuya ngesimo sokudla okunempilo. Amazinga e-Ghrelin ajwayele ukuba phezulu uma isisu singenalutho, okuvuselela ukukhiqizwa kwe-ghrelin ekhombisa ubuchopho ukuthi udinga ukudla ini. IGhrelin futhi inamazinga aphakeme kakhulu ezimweni zokungondleki njenge-anorexia ne-cachexia, ngokwesibonelo.

Amazinga e-Ghrelin aphansi ngemuva kokudla futhi, ikakhulukazi, ekukhulupheni. Olunye ucwaningo lukhombisa ukuthi amazinga aphezulu e-leptin anomthelela ekukhiqizeni i-ghrelin, anciphisa inani le-ghrelin ekhiqizwayo.