Nakhu Odinga Ukukwazi Ngemiphumela Eseceleni Yokugomela I-COVID Uma Unama-Cosmetic Filler

-Delile

• Okokuqala, uvame kangakanani lo mthelela ohlangothini ovela kumuthi wokugoma?
• Kungani umuntu onama-filler engase avuvuke ngemva kokuthola umgomo we-COVID-19?
• Okufanele Ukwenze Uma Ube Nezigcwalisi futhi Uhlela Ukuthola Umuthi Wokugoma i-COVID-19
• Buyekeza kwe-

Ngaphambi nje konyaka omusha, i-Food and Drug Administration ibike umphumela omusha wokugomela i-COVID-19 owawungalindelekile: ukuvuvukala kobuso.

Abantu ababili - oneminyaka engama-46 noneminyaka engama-51 - abebethole umuthi wokugoma weModerna COVID-19 ngesikhathi sokuhlolwa komtholampilo babhekana "nokuhlangana okwesikhashana" (okusho ohlangothini lobuso) ukuvuvukala kungakapheli izinsuku ezimbili kokuthola isilinganiso sabo sesibili sokudubula, ngokusho kombiko. Imbangela esolwayo yokuvuvukala? Ukugcwaliswa kwezimonyo. "Zombili lezi zifundo bezikade zinamakhompiyutha," kusho i-FDA kulo mbiko. Le nhlangano ayizange ihlanganyele eminye imininingwane, futhi nommemezeli weModerna akazange abuye UmumoIsicelo sokuphawula ngaphambi kokushicilelwa.

Uma unezigcwalisi zezimonyo noma ubuzicabangela, mhlawumbe unemibuzo ethile mayelana nokuthi yini ongayilindela uma uthola umuthi wokugoma i-COVID-19 - noma ngabe uvela eModerna, Pfizer, noma ezinye izinkampani ezingathola maduzane imvume yokusebenzisa isimo esiphuthumayo I-FDA. Nakhu okudingeka ukwazi.

Okokuqala, uvame kangakanani lo mthelela ohlangothini ovela kumuthi wokugoma?

Hhayi kakhulu. Ukuvuvukala kobuso akufakiwe ohlwini lwemiphumela emibi evamile yomgomo we-COVID-19 ovela kuCenters for Disease Control and Prevention. Futhi i-FDA ibhale imibiko emibili nje kuphela yalo mphumela ongemuhle kubantu abangaphezu kwabangama-30,000 ababambe iqhaza ezivivinyweni zokwelashwa zaseModerna (kuze kube manje, imiphumela engemihle ayikabikwa ngomuthi wokugoma kaPfizer noma eminye imigomo ye-COVID-19 yenye inkampani).

Lokho kusho, STAT, isayithi lezindaba zezokwelapha elibhale bukhoma isethulo se-FDA sale datha ngoDisemba, sabika umuntu wesithathu ecaleni likaModerna owathi baba ne-lip angioedema (ukuvuvukala) cishe ezinsukwini ezimbili ngemuva kokugoma (akucaci noma ngabe lokhu bekungemva kokuqala komuntu noma umthamo wesibili). "Lo muntu ubethole imijovo yangaphambi kokuhlinzwa emlonyeni," kusho uRachel Zhang, MD, osebenza kwezokwelapha e-FDA ngesikhathi ethula le nkulumo, ngokusho kuka STAT. UDkt. Zhang akazange acacise ukuthi lo muntu uyithole nini inqubo yakhe yokugcwalisa. (Okuhlobene: Konke Odinga Ukukwazi Mayelana Nemiphumela emibi ye-COVID-19 Vaccine Side)

Ngenkathi i-FDA ingashongo ukuthi bangaki abantu ecaleni likaModerna ababenezigcwalisi zezimonyo, cishe abantu abayizigidi ezintathu e-U.S. Bathola ukugcwaliswa minyaka yonke, ngokwe-American Society of Plastic Surgeons - ngakho-ke, kuyinqubo ejwayelekile. Kodwa ngezigameko ezintathu kuphela zokuvuvukala kobuso esivivinyweni esasihilela abantu abangaphezu kuka-30,000, lokho kusho ukuthi kunethuba elilinganiselwe elilodwa kwayizi-10 000 lokuthuthukisa ukuvuvukala kobuso ngemuva kokuthola umuthi wokugoma i-COVID-19. Ngamanye amagama: Akunakwenzeka.

Kungani umuntu onama-filler engase avuvuke ngemva kokuthola umgomo we-COVID-19?

Isizathu ngqo asikacaci okwamanje, kodwa ukuvuvukala "kungenzeka kube yinto ethize esebenza phakathi komuthi wokugoma kanye nezithako ezikulo," kusho uchwepheshe wezifo ezithathelwanayo u-Amesh A. Adalja, MD, isazi esiphakeme eJohns Hopkins Center for Ukuphepha Kwezempilo.

Izithako zomuthi wokugoma iModerna zifaka i-mRNA (i-molecule efundisa umzimba wakho ukuthi yakhe uhlobo lwayo lweprotein ye-spike yegciwane le-COVID-19 njengendlela yokulungisa umzimba wakho ukuzivikela kuleligciwane), izinhlobo ezahlukahlukene zama-lipids (amafutha ukusiza ukuthwala i-mRNA kumaseli afanele), i-tromethamine ne-tromethamine hydrochloride (ama-alkalizer avame ukusetshenziswa emithini yokugoma ukusiza ukufanisa izinga le-pH lomgomo nelemizimba yethu), i-acetic acid (i-asidi yemvelo evame ukutholakala kuviniga nayo kusiza ukugcina ukuzinza kwe-pH yokugoma), i-sodium acetate (uhlobo lukasawoti olusebenza njengesiqinisi se-pH somuthi futhi esivame ukusetshenziswa ku-IV fluid), kanye ne-sucrose (aka ushukela - esinye futhi isithako esivamile sokuqinisa imishanguzo ngokujwayelekile) .

Ngenkathi enye ye-lipids yomuthi wokugoma, i-polyethylene glycol, ixhunyaniswe nokungezwani komzimba esikhathini esedlule, uDkt Adalja uthi kunzima ukwazi ukuthi ngabe lesi sithako - noma esinye, salokho - sithinteka ngqo ekuvuvukala kwabantu abanezigcwalisi.

Umbiko we-FDA awucacisanga kahle ukuthi hlobo luni lokugcwalisa izimonyo lezi ziguli ezitholile. I-American Academy of Dermatology ithi izithako zokugcwalisa ezivame kakhulu, zifaka phakathi amafutha athathwe emzimbeni wakho, i-hyaluronic acid (ushukela otholakala ngokwemvelo emzimbeni onikeza ukonakala kwesikhumba, ukuqhuma nokukhanya), i-calcium hydroxylapatite (ngokuyisisekelo ifomu lokujova le-calcium elisiza ukukhuthaza ukukhiqizwa kwe-collagen yesikhumba), i-poly-L-lactic acid (i-asidi ephakamisa ukwakheka kwe-collagen), ne-polymethylmethacrylate (enye i-collagen booster). Ngayinye yalezi zigcwalisi ingeza nemiphumela yayo eyehlukile kanye nokusabela okwehlukile. Kodwa njengoba i-FDA ingazange icacise ukuthi yiluphi uhlobo (noma izinhlobo) zezigcwalisi laba bantu ababenazo, "akucaci ukuthi kungaba yini ukusabela okuphambene," kusho uDkt. Adalja. "Kunemibuzo eminingi esadinga ukuphendulwa." (Okuhlobene: Umhlahlandlela Ophelele Wokugcwalisa Imijovo)

Kuyathakazelisa ukuthi umuntu okubikwa ukuthi uvuvukele izindebe ngemuva kokugonyelwa i-Moderna COVID-19 uthe "babe nokusabela okufanayo ngemuva kokugomela umkhuhlane wangaphambilini," kusho uDkt Zhang ngesikhathi i-FDA yethula imininingwane yokugomela iModerna, ngokusho kukaDkt. STAT.

Enye yezincazelo ezingaba khona zalo mphumela oseceleni - noma ngabe wumuthi wokugoma kaModerna we-COVID-19, umkhuhlane, noma yimuphi omunye umuthi wokugoma - ukuthi "ukusebenza okuhlosiwe kwamasosha omzimba ngumuthi wokugoma nakho kungadala ukuvuvukala kwezinye izingosi emzimbeni, "kusho uJason Rizzo, MD, Ph.D., umqondisi weMohs Surgery eWestern New York Dermatology. "Njengoba i-dermal filler empeleni iyinto engaziwa emzimbeni, kuyaqondakala ukuthi lezi zindawo zingahle zivame ukuvuvukala nokuvuvukala kulolu hlobo lwesimo," kuchaza yena. (I-FYI: I-dermal filler ayifani ne-Botox.)

Okufanele Ukwenze Uma Ube Nezigcwalisi futhi Uhlela Ukuthola Umuthi Wokugoma i-COVID-19

Kuqoqwa idatha eyengeziwe mayelana nemiphumela engemihle yemithi yokugomela i-COVID-19 iyonke, kodwa kubalulekile ukunaka lokho okubikwe ngakho kuze kube manje - ngisho nemiphumela engemihle eye yabonakala ngamanani amancane kakhulu. Unalokho engqondweni, uDkt. Adalja uthi kungumqondo omuhle ukukhuluma nodokotela wakho wokunakekelwa okuyisisekelo uma uke wagcwalisa futhi uhlela ukugomela i-COVID-19.

Uma uthola ukuqhubeka, vele uqiniseke ukuthi uhlala ehhovisi lomhlinzeki wakho wezokwelapha imizuzu engaba ngu-15 kuya kwengu-30 ngemuva kokugonywa. (Umhlinzeki wakho kufanele alandele iziqondiso ze-CDC futhi atuse lokhu noma kunjalo, kodwa akukaze kube buhlungu ukukuphinda.) "Uma uthola ukuvuvukala, ungelashwa ngama-steroid noma ama-antihistamine, noma inhlanganisela yazo," kusho uDkt. Adalja. Uma kwenzeka uba nokuvuvukala kobuso (noma omunye umphumela ongalindelekile, ngalokho) ngemuva kokugonywa bese ushiya indawo yokugoma, uDkt Adalja uphakamisa ukubiza udokotela wakho ASAP ukuthola ukwelashwa okulungile.

Futhi, uma ubona ukuvuvukala kobuso (noma okunye okuphathelene nemiphumela engemihle) ngemuva komthamo wokuqala womuthi wakho wokugoma we-COVID-19, qiniseka ukuthi ukhuluma nodokotela wakho ngokuthi kungumbono omuhle yini ukuthola umthamo wesibili, kusho uRajeev Fernando , MD, uchwepheshe wezifo ezithathelwanayo osebenza ezibhedlela zasemkhakheni ze-COVID-19 ezweni lonke. Futhi, uma ukhathazekile ngalokho okungahle kudale ukuvuvukala, uDkt Fernando uphakamisa ukukhuluma nomuntu ongezwani nezinto zomzimba, ongakwazi ukwenza izivivinyo ezithile ukuze abone ukuthi yini engaba ngemuva komphumela ohlangothini.

UDkt. Adalja ugcizelela ukuthi lezi zindaba akufanele zikuvimbe ekutholeni umuthi wokugoma, noma ngabe uke wacabanga ukuthola ama-filler kungekudala. Kepha, uthi, "ungahle uthande ukuqaphela kancane izimpawu ohlangabezana nazo ngemuva kokuthola umuthi wokugoma, uma zikhona, bese unaka izindawo lapho ubugcwalise khona."

Sekukonke, noma kunjalo, uDkt. Adalja uthi "isilinganiso sengozi nenzuzo sithanda ukuthola umuthi wokugoma."

“Singakwelapha ukuvuvukala,” usho kanje, kodwa asikwazi njalo ukwelapha i-COVID-19 ngempumelelo.

Imininingwane ekule ndaba inembile njengesikhathi sokushicilela. Njengoba izibuyekezo mayelana ne-coronavirus COVID-19 ziqhubeka nokuvela, kungenzeka ukuthi ulwazi oluthile nezincomo kule ndaba kushintshile kusukela ekushicilelweni kokuqala. Sikukhuthaza ukuthi uhlole njalo izinsiza ezifana ne-CDC, i-WHO, kanye nomnyango wezempilo womphakathi wendawo ukuze uthole imininingwane yakamuva nezincomo.

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