Ukufakelwa kwe-Fecal: Ukhiye Wokuthuthukisa Impilo Ye-Gut?

-Delile

• Kuyini ukufakelwa kwendle?
• Kwenziwa kanjani?
• Colonoscopy
• Enema
• Ishubhu le-Nasogastric
• Amaphilisi
• Ingabe kubangela noma yimiphi imiphumela emibi?
• Ivelaphi indle?
• Ziyini izinzuzo zokwelapha ukutheleleka kuC.
• Kuthiwani ngezinzuzo zezinye izimo?
• I-irritable bowel syndrome (IBS)
• I-ulcerative colitis (UC)
• I-Autism spectrum disorder (ASD)
• Ukwehla kwesisindo
• Ngubani ongafanele ukufakelwa indle?
• Siyini isimo se-FDA?
• Kuthiwani ngokufakelwa kwendle kwe-DIY?
• Okubalulekile

Kuyini ukufakelwa kwendle?

Ukufakelwa kabusha kwendle kuyinqubo edlulisa indle isuke komnikeli iye emgodini wamathumbu (GI) womunye umuntu ngenhloso yokwelapha isifo noma isimo. Kubizwa nangokuthi i-fecal microbiota transplant (FMT) noma i-bacteriotherapy.

Ziya ngokuya zanda njengoba abantu bejwayela kakhulu ukubaluleka kwe-gut microbiome. Umqondo wokufakelwa kabusha kwendle ukuthi usiza ukwethula amabhaktheriya azuzisa kakhulu kupheshana lakho le-GI.

Ngokulandelayo, la mabhaktheriya awusizo angasiza ekulweni nezimo ezahlukahlukene zezempilo, kusuka ekungenweni yi-GI kuya kwi-autism spectrum disorder (ASD).

Kwenziwa kanjani?

Kunezindlela eziningana zokwenza ukufakelwa kwendle, ngayinye inezinzuzo zayo.

Colonoscopy

Le ndlela iletha ukulungiswa kwendle ketshezi ngqo emathunjini akho amakhulu nge-colonoscopy. Imvamisa, ityhubhu ye-colonoscopy iphushelwa emathunjini akho amakhulu. Njengoba ithubhu ihoxa, ifaka ukufakelwa emathunjini akho.

Ukusetshenziswa kwe-colonoscopy kunenzuzo yokuvumela odokotela ukuthi babone ngeso lengqondo izindawo zamathumbu akho amakhulu ezingalimala ngenxa yesimo esingaphansi.

Enema

Njengenqubo ye-colonoscopy, le ndlela ingenisa ukufakelwa ngqo emathunjini akho amakhulu nge-enema.

Ungacelwa ukuba ulale ngohlangothi lwakho ngenkathi umzimba wakho ophansi uphakanyisiwe. Lokhu kwenza kube lula ukuthi ukufakelwa kufinyelele emathunjini akho. Okulandelayo, ithiphu le-enema eligcotshisiwe lifakwa kahle ku-rectum yakho. Ukufakelwa kabusha, okusesikhwameni se-enema, bese kuvunyelwe ukugeleza ku-rectum.

Ukufakelwa kwe-fecal okunikezwe yi-enema ngokuvamile akuhlaseli kakhulu futhi kubiza kancane kunama-colonoscopies.

Ishubhu le-Nasogastric

Kule nqubo, ukulungiswa kwesitokisi esiwuketshezi kulethwa esiswini sakho ngebhubhu egijima ngamakhala akho. Kusuka esiswini sakho, ithuluzi bese liya emathunjini akho.

Okokuqala, uzonikezwa umuthi wokumisa isisu sakho ekukhiqizeni i-asidi engabulala izinto eziwusizo ekulungiseleleni ukufakelwa.

Okulandelayo, ishubhu lifakwa emakhaleni akho. Ngaphambi kwenqubo, uchwepheshe wezokunakekelwa kwempilo uzohlola ukubekwa kwephubhu esebenzisa ubuchwepheshe bezithombe. Uma isimiswe kahle, bazosebenzisa isirinji ukufutha ukulungiselela ngepayipi kanye nasesiswini sakho.

Amaphilisi

Le yindlela entsha yokufakelwa kabusha kwendle okubandakanya ukugwinya amaphilisi amaningi aqukethe ukulungiselela indle. Uma kuqhathaniswa nezinye izindlela, kuncane okungahlaseli futhi kungenziwa ngokujwayelekile ehhovisi lezokwelapha noma nasekhaya.

U-2017 uqhathanise le ndlela ne-colonoscopy kubantu abadala ephindaphindayo IClostridium difficile ukutheleleka. I-capsule ayibonakalanga ingasebenzi kangako kune-colonoscopy maqondana nokuvikela izifo eziphindaphindayo okungenani amasonto ayi-12.

Noma kunjalo, le ndlela yokugwinya ama-capsule idinga ukutadisha okuqhubekayo ukuqonda ngokugcwele ukusebenza nokuphepha kwayo.

Ingabe kubangela noma yimiphi imiphumela emibi?

Ukulandela ukufakelwa kwe-fecal, ungahle ube nemiphumela emibi embalwa, kufaka phakathi:

• ukungakhululeki esiswini noma ukuqunjelwa
• ukuqunjelwa
• ukuqunjelwa
• isifo sohudo
• ukubopha noma ukuqumba

Xhumana nomhlinzeki wakho wezempilo ngokushesha uma ubuhlungu buba bukhulu noma uhlangabezana nakho:

• ukuvuvukala okukhulu kwesisu
• ukuhlanza
• igazi esitokisini sakho

Ivelaphi indle?

Indle esetshenziselwa ukufakelwa indle ivela kubaxhasi babantu abanempilo. Ngokuya ngenqubo, indle ingenziwa ibe yisixazululo soketshezi noma yomiswe ibe yinto enamanzi.

Abantu abangaba banikeli kumele bahlolwe ngokwehlukahlukene, kufaka phakathi:

• ukuhlolwa kwegazi ukuhlola i-hepatitis, i-HIV, nezinye izimo
• indle ukuhlolwa namasiko ukuhlola izimuncagazi nezinye izimpawu zesimo esingaphansi

Abanikeli baphinde baqhubeke nenqubo yokuhlola ukuthola ukuthi:

• bathathe ama-antibiotic ezinyangeni eziyisithupha ezedlule
• Unesimiso sokuzivikela somzimba esibucayi
• ube nomlando wokuziphatha kocansi okuyingozi kakhulu, kufaka phakathi ukuya ocansini ngaphandle kokuvikelwa kwezihibe
• uthole umdwebo noma ukubhoboza umzimba ezinyangeni eziyisithupha ezedlule
• unomlando wokusetshenziswa kwezidakamizwa
• muva nje baye emazweni anezinga eliphezulu lokutheleleka ngezinambuzane
• unesimo esingelapheki se-GI, esifana nesifo samathumbu esivuthayo

Ungahle uhlangane namawebhusayithi ahlinzeka ngamasampuli endle ngeposi. Uma ucabanga ukufakelwa indle, qiniseka ukuthi usebenza nomhlinzeki wakho wezokunakekelwa kwezempilo ukuze uqinisekise ukuthi uthola isampula kumnikeli ofanelekayo.

Ziyini izinzuzo zokwelapha ukutheleleka kuC.

C. okuhlukileizifo zaziwa ngokuba nzima ukwelashwa. Mayelana nabantu abaphethwe ngemithi elwa namagciwane i C. okuhlukile ukutheleleka kuzoqhubeka nokwakha ukutheleleka okuphindaphindayo. Futhi, ukumelana namagciwane ku C. okuhlukile bekulokhu kwanda.

C. okuhlukile ukutheleleka kwenzeka lapho kunokuchichima kwamagciwane asepheshaneni lakho le-GI. Ngokusho kwe-American College of Gastroenterology, amaphesenti ama-5 kuye kwangama-15 abantu abadala abanempilo - namaphesenti angama-84.4 ezingane ezisanda kuzalwa nezinsana ezinempilo - anenani elijwayelekile C. okuhlukile emathunjini abo. Akubangeli izinkinga futhi kusiza ekugcineni inani lamagciwane ajwayelekile emathunjini.

Kodwa-ke, amanye amabhaktheriya emathunjini akho ngokuvamile agcina inani labantu be- C. okuhlukile isheke, ukuyivimba ukuthi ingabangeli ukutheleleka. Ukufakelwa kabusha kwe-fecal kungasiza ukuphinda ufake lawa mabhaktheriya epheshaneni lakho le-GI, okuwavumela ukuthi avimbele ukwanda kwesikhathi esizayo C. okuhlukile.

Iningi lezifundo ezikhona mayelana nokusetshenziswa kokufakelwa kwendle ekwelashweni kwe- C. okuhlukile izifo zincane. Kodwa-ke, iningi likhiqize imiphumela efanayo ekhombisa izinga lokwelashwa elingaphezu kuka.

Kuthiwani ngezinzuzo zezinye izimo?

Ochwepheshe basanda kucwaninga ukuthi ukufakelwa kwendle kungasiza kanjani kwezinye izimo nezinkinga zezempilo, kufaka phakathi ezinye izimo ze-GI. Ngezansi kunesifinyezo solunye locwaningo kuze kube manje.

Ngenkathi eminye yale miphumela ithembisa, kusenesidingo esikhulu sokwenza ucwaningo olwengeziwe kule ndawo ukuthola ukusebenza nokuphepha kokufakelwa kwendle kwalokhu kusetshenziswa.

I-irritable bowel syndrome (IBS)

Ukubuyekezwa kwakamuva nje kwezifundo eziyisishiyagalolunye kutholakale ukuthi ukufakelwa kwendle kuthuthukise izimpawu ze-IBS kubahlanganyeli. Kodwa-ke, lezi zifundo eziyisishiyagalolunye bezihluke kakhulu kunqubo yazo, isakhiwo kanye nokuhlaziywa kwazo.

I-ulcerative colitis (UC)

Izilingo ezine beziqhathanisa amazinga okuxolelwa e-UC kubantu abebethole ukufakelwa kwe-fecal kuqhathaniswa ne-placebo. Labo abathola ukufakelwa indle babenesilinganiso sokuxolelwa esingamaphesenti angama-25, uma kuqhathaniswa namaphesenti ama-5 kulabo abaseqenjini le-placebo.

Gcina ukhumbula ukuthi ukuthethelelwa kubhekisa enkathini yesikhathi ngaphandle kwezimpawu. Abantu abane-UC abasethethelweni basengaqhubeka nokuthola ukuqhuma noma izimpawu zesikhathi esizayo.

I-Autism spectrum disorder (ASD)

Okuncane kutholakale ukuthi uhlobo olwandisiwe lokufakelwa kwendle okuhlala isikhathi esingamasonto ayisikhombisa kuya kwayisishiyagalombili lwehlise izimpawu zokugaya ukudla ezinganeni ezine-ASD. Izimpawu zokuziphatha ze-ASD zibonakala zithuthuka futhi.

Lokhu kuthuthukiswa kusabonakala emasontweni ayisishiyagalombili ngemuva kokwelashwa.

Ukwehla kwesisindo

Okusanda kwenzeka kumagundane kubandakanye amaqembu amabili: elilodwa londla ukudla okunamafutha amaningi kanti elinye londle ukudla okunamafutha ejwayelekile futhi lafakwa ohlotsheni lokuvivinya umzimba.

Amagundane ekudleni okunamafutha aphezulu athola ukufakelwa kwendle kusuka kumagundane eqenjini lesibili. Lokhu kuvele ukunciphisa ukuvuvukala nokwenza ngcono imetabolism. Baze bakhomba amagciwane amaningi ahambisana nale miphumela, noma kungacaci ukuthi le miphumela izohumusha kanjani kubantu.

Funda kabanzi mayelana nokuxhumana phakathi kwesisindo namathumbu amabhaktheriya.

Ngubani ongafanele ukufakelwa indle?

Ukufakelwa kwe-fecal akunconyelwe abantu abangakwazi ukuzivikela ngenxa yokuthi:

• izidakamizwa ezicindezela amasosha omzimba
• I-HIV
• isifo sesibindi esithuthukile, njenge-cirrhosis
• ukufakelwa umnkantsha wamuva nje

Siyini isimo se-FDA?

Ngenkathi ucwaningo oluzungeze ukufakelwa kwendle luthembisa, i-Food and Drug Administration (i-FDA) ayikabavumeli ukusetshenziswa kwanoma yimuphi umtholampilo futhi ibabheka njengesidakamizwa sokuphenya.

Ekuqaleni, odokotela abafuna ukusebenzisa ukufakelwa kwendle kwakudingeka bafake isicelo ku-FDA ngaphambi kokwenza inqubo. Lokhu kubandakanya inqubo ende yokugunyaza edikibalise abaningi ekusebenziseni ukufakelwa kwendle.

I-FDA isikhululile le mfuneko yokufakelwa indle okuhloswe ngayo ukwelapha okuphindayo C. okuhlukile izifo ezingaphendulanga kuma-antibiotic. Kepha odokotela kusadingeka bafake izicelo zanoma ikuphi ukusetshenziswa ngaphandle kwalesi simo.

Kuthiwani ngokufakelwa kwendle kwe-DIY?

I-inthanethi igcwele mayelana nokuthi ungenza kanjani ukufakelwa kwendle ekhaya. Futhi ngenkathi umzila we-DIY ungazwakala uyindlela enhle yokuzungeza imithethonqubo ye-FDA, ngokuvamile akuwona umqondo omuhle.

Nazi izizathu ezimbalwa zokuthi kungani:

• Ngaphandle kokuhlolwa okufanele kwabanikeli, kungenzeka ukuthi uzibeka engcupheni yokuthola isifo.
• Odokotela abenza ukufakelwa kwendle banokuqeqeshwa okubanzi kokuthi ungenza kanjani ngokuphepha isitulo sokulungiselela ukufakelwa.
• Ucwaningo ngemiphumela yesikhathi eside nokuphepha kokufakelwa kwendle lusakhawulelwe, ikakhulukazi ngezimo ezingezona C. okuhlukile ukutheleleka.

Okubalulekile

Ukufakelwa kukaFecal kuyindlela ethembisayo yokwelashwa yezimo ezahlukahlukene. Namuhla, zisetshenziselwa okuyinhloko ukwelapha okuphindayo C. okuhlukile izifo.

Njengoba ochwepheshe befunda kabanzi ngokufakwa kwendle, bangaba inketho yezinye izimo, kusuka ezindabeni ze-GI kuye ezimweni ezithile zentuthuko.