I-Epirubicin

-Delile

• Ngaphambi kokuthola umjovo we-epirubicin,
• I-Epirubicin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Epirubicin kufanele inikezwe kuphela emthanjeni. Kodwa-ke, ingahle ivuze izicubu eziseduze ezibangele ukucasuka okukhulu noma ukulimala. Udokotela wakho noma umhlengikazi uzoqapha indawo yakho yokuphatha ngale ndlela. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu, ukulunywa, ubomvu, ukuvuvukala, amabhamuza, noma izilonda endaweni lapho umjovo wafakwa khona.

I-Epirubicin ingadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo nganoma yisiphi isikhathi phakathi nokwelashwa kwakho noma izinyanga kuya eminyakeni ngemuva kokuphela kokwelashwa kwakho. Udokotela wakho uzo-oda ukuhlolwa ngaphambi nangesikhathi sokwelashwa kwakho ukuze abone ukuthi inhliziyo yakho isebenza kahle ngokwanele yini ukuthola i-epirubicin ngokuphepha. Lezi zivivinyo zingafaka i-electrocardiogram (ECG; ukuhlolwa okurekhoda umsebenzi kagesi wenhliziyo) kanye ne-echocardiogram (ukuhlolwa okusebenzisa amaza omsindo ukukala amandla enhliziyo yakho okumpompa igazi). Udokotela wakho angakutshela ukuthi akufanele uthole le mithi uma izivivinyo zibonisa ukuthi amandla enhliziyo yakho okupompa igazi anciphile. Tshela udokotela wakho uma ngabe uke waba nanoma yiluphi uhlobo lwesifo senhliziyo noma ukwelashwa ngemisebe (x-ray) endaweni yesifuba. Tshela udokotela wakho kanye nosokhemisi uma uthatha noma wake wathola imithi ethile yokwelashwa ngamakhemikhali efana ne-daunorubicin (Cerubidine), doxorubicin (Doxil), idarubicin (Idamycin), mitoxantrone (Novantrone), cyclophosphamide (Cytoxan), noma i-trastuzumab (Herceptin). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuphefumula okuncane; ukuphefumula kanzima; ukuvuvukala kwezandla, izinyawo, amaqakala noma imilenze engezansi; noma ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla.

I-Epirubicin ingakhuphula ubungozi bokuthola i-leukemia (umdlavuza wamaseli amhlophe egazi), ikakhulukazi uma inikezwa ngemithamo ephezulu noma kanye neminye imithi ethile yokwelashwa ngamakhemikhali.

I-Epirubicin ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho wethambo. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulinyazwa.

I-Epirubicin kufanele inikezwe kuphela ngaphansi kokuqondisa kukadokotela onolwazi ekusetshenzisweni kwemithi yokwelapha ngamakhemikhali.

Khuluma nodokotela wakho ngengozi yokuthola i-epirubicin.

I-Epirubicin isetshenziswa ngokuhlangana neminye imishanguzo yokwelapha umdlavuza webele ezigulini ezihlinzwe ukukhipha isimila. I-Epirubicin isekilasini lemithi ebizwa ngama-anthracyclines. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

I-Epirubicin iza njengesisombululo (uketshezi) sokujova ngomjovo (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha kanye neminye imithi yokwelashwa ngamakhemikhali. Ingafakwa kanye ezinsukwini ezingama-21 ngemijikelezo eyisithupha yokwelashwa noma ingajova kabili (ngezinsuku 1 no-8) njalo ezinsukwini ezingama-28 ngemijikelezo eyisithupha yokwelashwa.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-epirubicin,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-epirubicin, daunorubicin (Cerubidine, DaunoXome), doxorubicin (Doxil), idarubicin (Idamycin), noma imiphi eminye imithi, noma iziphi izithako zomjovo we-epirubicin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nokunye okulandelayo: ama-calcium channel blocker anjenge-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), kanye ne-verapamil (Calan, Isoptin, Verelan); imithi ethile ye-chemotherapy efana ne-docetaxel (Taxotere) noma i-paclitaxel (i-Abraxane, i-Onxol); noma i-cimetidine (Tagamet). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo ingaxhumana ne-epirubicin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi wake wakuthola yini ukwelashwa ngemisebe noma wake waba nesifo sesibindi noma sezinso.
• kufanele wazi ukuthi i-epirubicin ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane futhi ingamisa ukukhiqizwa kwesidoda emadodeni. Kodwa-ke, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukuthola lo muthi. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola umjovo we-epirubicin. Uma ukhulelwa ngenkathi uthola i-epirubicin, shayela udokotela wakho. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. I-Epirubicin ingalimaza umbungu.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Epirubicin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• izilonda emlonyeni nasemphinjeni
• ubuhlungu besisu
• isifo sohudo
• ukulahlekelwa isifiso sokudla noma isisindo
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukulahleka kwezinwele
• ukushisa okushisayo
• ukuguqulwa okubomvu komchamo (izinsuku eziyi-1 kuya kwezi-2 ngemuva komthamo)
• amehlo abuhlungu noma abomvu
• ubuhlungu beso
• ukufiphala kwesikhumba noma kwezipikili

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isikhumba esiphaphathekile
• ukuquleka
• isiyezi
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya

I-Epirubicin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• izilonda emlonyeni nasemphinjeni
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza okunegazi
• okokuhlanza okubukeka njengezizathu zekhofi

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-epirubicin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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