Kuyini I-Lymphoma Yokulandela?

-Delile

• Isigameko
• Izimpawu
• Ukuxilongwa
• Ukwelashwa
• Ukulinda okulindile
• Imisebe
• Ukwelashwa ngamakhemikhali
• Amasosha omzimba angama-monoclonal
• I-Radioimmunotherapy
• Ukufakelwa kwe-stem cell
• Izinkinga
• Ukubuyiselwa
• Umbono

Ukubuka konke

I-follicular lymphoma uhlobo lomdlavuza oqala kumaseli amhlophe egazi lomzimba wakho. Kunezinhlobo ezimbili eziyinhloko ze-lymphoma: iHodgkin ne-non-Hodgkin. I-follicular lymphoma iyi-non-Hodgkin lymphoma.

Lolu hlobo lwe-lymphoma luvame ukukhula kancane, odokotela abakubiza ngokuthi “ukuvilapha.”

Funda ukuze ufunde kabanzi mayelana nezimpawu ze-follicular lymphoma nokuthi yiziphi izinketho zokwelashwa ezitholakalayo.

Isigameko

I-non-Hodgkin lymphoma ingenye yomdlavuza ovame kakhulu e-United States. Bangaphezu kuka-72,000 abantu abatholakala benohlobo lwayo unyaka nonyaka.

Cishe eyodwa kwama-lymphomas amahlanu e-United States yi-follicular lymphoma.

I-lymphoma yesibindi ayithinti kakhulu abantu abasha. Isilinganiso seminyaka yomuntu onalolu hlobo lomdlavuza cishe singama-60.

Izimpawu

Izimpawu ze-follicular lymphoma zingafaka:

• ama-lymph node akhulisiwe entanyeni, ngaphansi kwekhwapha, esiswini noma emgodini
• ukukhathala
• ukuphelelwa umoya
• imfiva noma ukujuluka ebusuku
• ukuncipha komzimba
• izifo

Abanye abantu abane-follicular lymphoma abanazo izimpawu nhlobo.

Ukuxilongwa

Ukuthola i-follicular lymphoma, udokotela wakho angenza izivivinyo ezilandelayo:

• Isidumbu. I-biopsy yenziwa ukuhlola izicubu ngaphansi kwesibonakhulu bese kunqunywa ukuthi inomdlavuza yini.
• Ukuhlolwa kwegazi. Ungadinga ukuhlolwa ukuhlola ukubalwa kwamaseli akho egazi.
• Ukuthwebula ukuskena. Udokotela wakho angase asikisele ukuthi uskene isithombe ukuze ubone i-lymphoma emzimbeni wakho nokuhlela ukwelashwa kwakho. Izikena ze-computed tomography (CT) ne-positron emission tomography (PET) zivame ukusetshenziswa.

Ukwelashwa

Izinketho zokwelashwa eziningana ziyatholakala kubantu abane-follicular lymphoma. Udokotela wakho uzonquma ukuthi iluphi uhlobo lokwelashwa olulungele wena ngokuya ngohlobo lwakho lomdlavuza nokuthi luthuthuke kangakanani.

Ukulinda okulindile

Uma utholakala kusenesikhathi futhi unezimpawu ezimbalwa kuphela, udokotela wakho angase asikisele ukuthi ubuke futhi ulinde. Lokhu kusho ukuthi umhlinzeki wakho wezokunakekelwa kwempilo uzobheka isimo sakho, kodwa ngeke uthole ukwelashwa okwamanje.

Imisebe

Imisebe isebenzisa imishayo enamandla amakhulu ukubhubhisa amangqamuzana omdlavuza. Kuvame ukunikezwa abantu abane-follicular lymphoma yokuqala. Kwezinye izimo, imisebe iyodwa ingakwazi ukwelapha lolu hlobo lomdlavuza. Ungadinga imisebe kanye nezinye izindlela zokwelapha uma umdlavuza wakho usuthuthuke kakhulu.

Ukwelashwa ngamakhemikhali

I-Chemotherapy isebenzisa izidakamizwa ukubulala amangqamuzana omdlavuza emzimbeni wakho. Kwesinye isikhathi kunikezwa abantu abane-follicular lymphoma, futhi kuvame ukuhlanganiswa nezinye izindlela zokwelapha.

Amasosha omzimba angama-monoclonal

Ama-antibody e-monoclonal yimithi ekhomba izimpawu ezithile kwizicubu futhi isiza amaseli akho omzimba alwe nomdlavuza. I-Rituximab (i-Rituxan) i-anti-monoclonal antibody evame ukusetshenziswa ukwelapha i-follicular lymphoma. Ngokuvamile kunikezwa njengokufakwa kwe-IV ehhovisi likadokotela wakho futhi kuvame ukusetshenziswa ngokuhlanganiswa ne-chemotherapy.

Ukuhlanganiswa okuvamile kufaka:

• r-bendamustine (rituximab ne-bendamustine)
• R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, ne-prednisone)
• I-R-CVP (rituximab, cyclophosphamide, vincristine, ne-prednisone)

I-Radioimmunotherapy

I-Radioimmunotherapy ihilela ukusebenzisa umuthi i-yttrium-90 ibritumomab tiuxetan (Zevalin) ukuletha imisebe kumaseli womdlavuza.

Ukufakelwa kwe-stem cell

Ukufakelwa kwe-stem cell kwesinye isikhathi kusetshenziselwa i-follicular lymphoma, ikakhulukazi uma umdlavuza wakho ubuya. Le nqubo ifaka ukufaka amaseli ezinhlayiya anempilo emzimbeni wakho ukuze angene esikhundleni somnkantsha onezifo.

Kunezinhlobo ezimbili zokufakelwa kwe-stem cell:

• Ukufakelwa kwe-Autologous. Le nqubo isebenzisa amaseli akho we-stem ukwelapha umdlavuza wakho.
• Ukufakelwa kabusha kwe-allogeneic. Le nqubo isebenzisa amaseli ama-stem enempilo avela kumnikeli.

Izinkinga

Lapho i-lymphoma ekhula kancane, njenge-follicular lymphoma, iphenduka ifomu elikhula ngokushesha, yaziwa njenge-lymphoma eguquliwe. I-lymphoma eshintshiwe ivame ukuba nolaka kakhulu futhi ingadinga ukwelashwa okunzima kakhulu.

Amanye ama-lymphomas angama-follicular angaphenduka uhlobo olukhula ngokushesha lwe-lymphoma olubizwa ngokuthi ukusabalalisa okukhulu kwe-B-cell lymphoma.

Ukubuyiselwa

Ngemuva kokwelashwa okuphumelelayo, abantu abaningi abane-follicular lymphoma bazongena ekuxolelweni. Noma lokhu kuxolelwa kungahlala iminyaka, i-follicular lymphoma ibhekwa njengesimo sempilo yonke.

Lo mdlavuza ungabuya, futhi kwesinye isikhathi, abantu ababuyela emuva abaphenduli ekwelashweni.

Umbono

Ukwelashwa kwe-follicular lymphoma kuvame ukusetshenziselwa ukugcina isifo silawulwa kunokulapha isimo. Lo mdlavuza uvame ukuphathwa ngempumelelo iminyaka eminingi.

Odokotela benze i-Follicular Lymphoma International Prognostic Index (FLIPI) ukusiza ukuhlinzekela ukubikezelwa kwalolu hlobo lomdlavuza. Lolu hlelo lusiza ukuhlukanisa i-follicular lymphoma ngezigaba ezintathu:

• ingozi ephansi
• ubungozi obuphakathi
• ingozi enkulu

Ingozi yakho ibalwa ngokuya "ngezinto zokubikezela," ezibandakanya izinto ezifana nobudala, isigaba somdlavuza wakho, nokuthi mangaki ama-lymph node athintekile.

Isilinganiso seminyaka emihlanu sokusinda kwabantu abane-follicular lymphoma abasengozini ephansi (abanaso noma esisodwa kuphela isici esibi sokubikezela) singamaphesenti angama-91. Kulabo abanobungozi obuphakathi nendawo (izinto ezimbili ezimbi zokubikezela), isilinganiso seminyaka emihlanu sokusinda singamaphesenti angama-78. Uma usengozini enkulu (izici ezintathu noma ngaphezulu zokuxela okubi), isilinganiso seminyaka emihlanu sokusinda singamaphesenti angama-53.

Amanani okusinda anganikeza imininingwane ewusizo, kodwa angukulinganisela kuphela futhi awakwazi ukubikezela okuzokwenzeka esimweni sakho esithile. Khuluma nodokotela wakho ngombono wakho othize nokuthi yiziphi izinhlelo zokwelashwa ezilungele isimo sakho.