Yini i-galactorrhea, izimbangela eziyinhloko nokwelashwa
-Delile
IGalactorrhea yimfihlo engafanele yoketshezi oluqukethe ubisi olusuka ebeleni, oluvela emadodeni noma kwabesifazane abangakhulelwe noma abancelisayo. Imvamisa kuyisibonakaliso esidalwa ukwanda kwe-prolactin, i-hormone ekhiqizwa ebuchosheni umsebenzi wayo ukwenza ukwakheka kobisi ngamabele, isimo esibizwa nge-hyperprolactinemia.
Izimbangela ezinkulu zokwanda kweprolactin ukukhulelwa nokuncelisa ibele, futhi kunezimbangela eziningi zokwanda kwayo okungafanele, kufaka phakathi isimila sobuchopho besifo, ukusetshenziswa kwemithi, njengamanye ama-neuroleptics kanye ne-anti-depressants, ukugqugquzela amabele noma ezinye izifo ze-endocrine, njenge-hypothyroidism kanye i-polycystic ovary syndrome.
Ngakho-ke, ukwelapha i-hyperprolactinemia kanye ne-galactorrhea, kuyadingeka ukuxazulula imbangela yayo, kungaba ngokususa umuthi noma ukwelapha isifo esinciphisa ukukhiqizwa kobisi ngamabele.
Izimbangela eziyinhloko
Izimbangela eziyinhloko zokukhiqizwa kobisi ngamabele ukukhulelwa nokuncelisa, kepha i-galactorrhea yenzeka, ikakhulukazi ngenxa yezimo ezinjengalezi:
- I-pituitary adenoma: kuyisimila esibi se-pituitary gland, esibhekele ukukhiqizwa kwamahomoni amaningi, kufaka phakathi i-prolactin. Uhlobo oluyinhloko yi-prolactinoma, okuvame ukudala ukwanda kwamazinga e-prolactin egazi amakhulu kune-200mcg / L;
- Ezinye izinguquko ku-pituitary gland: umdlavuza, i-cyst, ukuvuvukala, imisebe noma imivimbo yobuchopho, isibonelo;
- Ukukhuthazwa kodonga lwamabele noma lwesifuba: isibonelo esiyinhloko sokugqugquzela ukuncela amabele ngumntwana, okwenza kusebenze izindlala ezincelisayo futhi kuqinise ukukhiqizwa kwe-cerebral prolactin futhi, ngenxa yalokho, ukukhiqizwa ubisi;
- Izifo ezidala ukuphazamiseka kwamahomoni: ezinye zazo eziyinhloko i-hypothyroidism, i-cirrhosis yesibindi, ukwehluleka okungapheli kwezinso, isifo se-Addison kanye ne-polycystic ovary syndrome;
- Umdlavuza webele: kungadala i-galactorrhea engonweni eyodwa, imvamisa inegazi;
- Ukusetshenziswa kwemithi:
- Ama-Antipsychotic, afana neRisperidone, Chlorpromazine, Haloperidol noma iMetoclopramide;
- Ama-opiates, afana ne-Morphine, Tramadol noma i-Codeine;
- Ama-gastric acid reducers, afana neRanitidine noma iCimetidine;
- Ama-anti-depressants, afana ne-Amitriptyline, Amoxapine noma iFluoxetine;
- Ezinye izidakamizwa ezinomfutho wegazi ophezulu, njengeVerapamil, Reserpina neMetildopa;
- Ukusetshenziswa kwamahomoni, njenge-estrogens, anti-androgens noma i-HRT.
Ukulala nokucindezeleka ezinye izimo ezibangela ukwanda kokukhiqizwa kwe-prolactin, kepha-ke, kuyaqabukela kubangele izinguquko ezanele ukudala i-galactorrhea.
Izimpawu ezivamile
IGalactorrhea uphawu oluyinhloko lwe-hyperprolactinemia, noma i-prolactin eyeqile emzimbeni, futhi ingahle iveze obala, ibe nobisi noma inegazi ngombala, futhi ivele kwelinye noma kuwo womabili amabele.
Kodwa-ke, kungavela ezinye izimpawu nezimpawu, ngoba ukwanda kwale hormone kungadala ushintsho kuma-hormone ezocansi, njengokuncipha kwe-estrogen ne-testosterone, noma, futhi, uma kukhona izimila endlaleni yebhinqa. Izimpawu eziyinhloko yilezi:
- I-Amenorrhea, okungukuphazamiseka kokuvuthwa nokuya esikhathini kwabesifazane;
- Ukungabi namandla ocansini kanye nokungasebenzi kahle kwamadoda emadodeni;
- Ukungabi nenzalo nokwehla kwesifiso sobulili;
- Ukukhumuzeka kwamathambo;
- Ikhanda;
- Izinguquko ezibukwayo, ezinjenge-turbidity nokubona kwamabala akhanyayo.
Izinguquko zeHormonal nazo zingabhekela ukungabi nenzalo kwabesilisa noma kwabesifazane.
Ungayixilonga kanjani
I-Galactorrhea ibonwa ekuhlolweni kwemitholampilo yezokwelapha, okungaba okuzenzakalelayo noma ukuvela ngemuva kokuvezwa kwengono. IGalactorrhea iqinisekiswa noma nini lapho uketshezi lobisi lwenzeka emadodeni, noma uma luvela kwabesifazane abangakhulelwe noma abancelisayo ezinyangeni eziyisithupha ezidlule.
Ukuthola imbangela ye-galactorrhea, udokotela uzohlola umlando wemithi nezinye izimpawu umuntu angahlangabezana nazo. Ngaphezu kwalokho, ezinye izivivinyo zingenziwa ukuphenya imbangela ye-galactorrhea, njengokukalwa kweprolactin egazini, ukulinganiswa kwamanani we-TSH ne-T4, ukuphenya ukusebenza kwe-thyroid, futhi, uma kunesidingo, i-MRI yobuchopho ukuphenya ubukhona bezimila noma olunye ushintsho ku-pituitary gland.
Yelashwa kanjani
Ukwelashwa kwe-galactorrhea kuqondiswa yi-endocrinologist, futhi kuyahlukahluka ngokuya ngezimbangela zesifo. Uma kungumphumela oseceleni womuthi, kufanele ukhulume nodokotela ukuze ahlole ukuthi kungenzeka yini ukumiswa noma ukuphindiselwa kwalo muthi ngomunye.
Uma sibangelwa yisifo, kubalulekile ukuthi siphathwe kahle, ukuze kuzinze ukuphazamiseka kwamahomoni, njengesibonelo, ukushintshwa kwamahomoni wegilo ku-hypothyroidism, noma ukusetshenziswa kwama-corticosteroids ama-pituitary granulomas. Noma, lapho i-galactorrhea ibangelwa isimila, udokotela angancoma ukwelashwa ngokususwa kokuhlinzwa noma izinqubo ezifana ne-radiotherapy.
Ngaphezu kwalokho, kukhona izidakamizwa ezinganciphisa ukukhiqizwa kwe-prolactin nokulawula i-galactorrhea, ngenkathi ukwelashwa okucacile kwenziwa, njengeCabergoline neBromocriptine, okuyizidakamizwa ezisesigabeni sabaphikisi be-dopaminergic.