IGemfibrozil, Ithebhulethi Yomlomo

-Delile

• Izexwayiso ezibalulekile
• Yini i-gemfibrozil?
• Kungani kusetshenziswa
• Isebenza kanjani
• Imiphumela emibi ye-Gemfibrozil
• Imiphumela emibi ejwayelekile
• Imiphumela emibi kakhulu
• IGemfibrozil ingaxhumana neminye imithi
• Ukungezwani komzimba nesifo somoya
• Isidakamizwa esinciphisa igazi
• Izidakamizwa zomdlavuza
• Isidakamizwa sohudo
• Izidakamizwa ze-cholesterol
• Izidakamizwa zikashukela
• Isidakamizwa se-Gout
• Isidakamizwa se-Hepatitis C
• Umuthi we-pulmonary arterial hypertension (PAH)
• Izexwayiso zeGemfibrozil
• Isexwayiso somzimba
• Izexwayiso zabantu abanezimo ezithile zempilo
• Izexwayiso kwamanye amaqembu
• Ungayithatha kanjani i-gemfibrozil
• Amafomu wezidakamizwa namandla
• Isikali se-cholesterol ephezulu
• Thatha njengoba kuqondisiwe
• Ukucatshangelwa okubalulekile kokuthatha i-gemfibrozil
• Jikelele
• Isitoreji
• Ukugcwalisa kabusha
• Ukuvakasha
• Ukuqapha komtholampilo
• Ukudla kwakho
• Ingabe zikhona ezinye izindlela?

Amaphuzu avelele we-gemfibrozil

1. Ithebhulethi yomlomo yeGemfibrozil iyatholakala njengesidakamizwa esinegama lomuthi kanye nomuthi ojwayelekile. Igama lomkhiqizo: Lopid.
2. I-Gemfibrozil iza kuphela ngendlela yethebhulethi oyithatha ngomlomo.
3. IGemfibrozil isetshenziselwa ukwehlisa ama-triglycerides, uhlobo lwamafutha egazini lakho. Ukuba namazinga aphakeme kakhulu e-triglycerides kukhulisa ingozi yokuba ne-pancreatitis (ukuvuvukala kwamanyikwe).

Izexwayiso ezibalulekile

• Isexwayiso se-Gallstones: I-Gemfibrozil ingakudalela ukuba wakhe amatshe enyongo. Uma uthuthukisa ama-gallstones, kufanele uyeke ukusebenzisa lesi sidakamizwa.
• Ukuhlanganiswa nesexwayiso sezimiso: IGemfibrozil akufanele ithathwe nge-simvastatin, esinye isidakamizwa se-cholesterol. Sebenzisa i-gemfibrozil nge-simvastatin noma ezinye izidakamizwa esigabeni se-statin kungahle kube nobuthi obukhulu bemisipha. Lesi simo singadala ukwehluleka kwezinso noma ukufa.

Sebenzisa ngesexwayiso selexipag: I-Gemfibrozil akufanele ithathwe nge-selexipag, esetshenziselwa ukwelapha umfutho wegazi ophakeme wamaphaphu (PAH). Ukusebenzisa le mithi ndawonye kungakhuphula inani le-selexipag emzimbeni wakho emazingeni ayingozi.

Yini i-gemfibrozil?

IGemfibrozil ngumuthi kadokotela. Kuza njengethebhulethi oyithatha ngomlomo.

IGemfibrozil iyatholakala njengesidakamizwa esinegama lomkhiqizo I-Lopid. Iphinde itholakale njengomuthi ojwayelekile. Imithi ejwayelekile ijwayele ukubiza imali encane kunohlobo lwamagama. Kwezinye izimo, kungenzeka zingatholakali ngawo wonke amandla noma ifomu njengesidakamizwa esinegama lomkhiqizo.

Kungani kusetshenziswa

IGemfibrozil isetshenziselwa ukwehlisa amazinga akho e-triglycerides, uhlobo lwamafutha egazini lakho. Amazinga aphezulu kakhulu e-triglycerides akhulisa ubungozi be-pancreatitis.

Isebenza kanjani

IGemfibrozil ingeyesigaba semithi ebizwa nge-fibric acid derivatives. Isigaba semithi siyiqembu lemithi esebenza ngendlela efanayo. Le mithi ivame ukusetshenziselwa ukwelapha izimo ezifanayo.

IGemfibrozil isebenza ngokuguqula inani le-cholesterol namanye amafutha (lipids) emzimbeni wakho. IGemfibrozil yehlisa amazinga e-triglyceride futhi inyuse amazinga e-cholesterol e-HDL. (I-HDL ibhekwa njengohlobo oluhle lwe-cholesterol.)

Imiphumela emibi ye-Gemfibrozil

IGemfibrozil ayibangeli ukozela, kepha ingadala eminye imiphumela emibi.

Imiphumela emibi ejwayelekile

Imiphumela emibi ejwayelekile engenzeka ngokusetshenziswa kwe-gemfibrozil ifaka:

• ukucasuka kwesisu
• ubuhlungu besisu
• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukuqubuka
• isiyezi
• ikhanda
• izinguquko endleleni izinto ezinambitha ngayo
• ubuhlungu bemisipha

Uma le miphumela imnene, ingahle ihambe zingakapheli izinsuku ezimbalwa noma amasonto ambalwa. Uma zinzima kakhulu noma zingahambi, khuluma nodokotela wakho noma usokhemisi.

Imiphumela emibi kakhulu

Shayela udokotela wakho ngokushesha uma unemiphumela emibi kakhulu. Shayela u-911 uma izimpawu zakho zizizwa zisongela impilo noma uma ucabanga ukuthi unezimo eziphuthumayo zezokwelapha. Imiphumela emibi kanye nezimpawu zayo zingafaka okulandelayo:

• Amatshe amatshe amade. Izimpawu zingafaka:
  • ubuhlungu engxenyeni engenhla yesisu sakho (indawo yesisu)
  • isicanucanu
  • ukuhlanza
• I-Rhabdomyolysis (ubuthi bemisipha). Izimpawu zingafaka:
  • ubuhlungu, isisa, noma ubuthakathaka emisipheni yakho
  • umchamo onombala omnyama

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zithinta umuntu ngamunye ngokuhlukile, asikwazi ukuqinisekisa ukuthi lolu lwazi lubandakanya yonke imiphumela emibi engaba khona. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala uxoxa ngemiphumela emibi engaba khona nomhlinzeki wezokunakekelwa kwempilo owazi umlando wakho wezokwelapha.

IGemfibrozil ingaxhumana neminye imithi

Ithebhulethi yomlomo yeGemfibrozil ingaxhumana neminye imishanguzo, amavithamini, noma amakhambi okungenzeka ukuthi uthatha. Ukusebenzisana kulapho into iguqula indlela umuthi osebenza ngayo. Lokhu kungaba yingozi noma kuvimbele umuthi ukuthi usebenze kahle.

Ukusiza ukugwema ukuxhumana, udokotela wakho kufanele aphathe yonke imithi yakho ngokucophelela. Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi, amavithamini, noma amakhambi owathathayo. Ukuthola ukuthi lo muthi ungahlangana kanjani nokunye okuthathayo, khuluma nodokotela wakho noma usokhemisi.

Izibonelo zezidakamizwa ezingadala ukusebenzisana ne-gemfibrozil zibalwe ngezansi.

Ukungezwani komzimba nesifo somoya

I-Montelukast isetshenziselwa ukwelapha ukungezwani komzimba nesifuba somoya. Ukuthatha i-gemfibrozil ngayo kungandisa ubungozi bemiphumela emibi. Udokotela wakho angehlisa isilinganiso sakho salesi sidakamizwa uma udinga ukusithatha nge-gemfibrozil.

Isidakamizwa esinciphisa igazi

I-Warfarin isetshenziselwa ukunciphisa igazi. Uma isetshenziswa nge-gemfibrozil, imiphumela ye-warfarin ingakhuphuka. Lokhu kuphakamisa ingozi yakho yokopha. Udokotela wakho anganciphisa isilinganiso sakho se-warfarin futhi akuqaphele kaningi lapho uqala i-gemfibrozil.

Izidakamizwa zomdlavuza

Ukuthatha imishanguzo ethile yomdlavuza nge-gemfibrozil kungakhuphula imiphumela yalezo zidakamizwa zomdlavuza. Udokotela wakho anganciphisa isilinganiso sakho sale mithi uma udinga ukuyithatha nge-gemfibrozil. Izibonelo zale mithi zifaka:

• dabrafenib
• enzalutamide
• hbokuhle

Isidakamizwa sohudo

I-Loperamide isetshenziselwa ukwelapha isifo sohudo. Uma isetshenziswa nge-gemfibrozil, imiphumela ye-loperamide ingakhuphuka. Udokotela wakho anganciphisa isilinganiso sakho se-loperamide uma udinga ukuyithatha nge-gemfibrozil.

Izidakamizwa ze-cholesterol

Imithi ethile ebuye yehlise i-cholesterol inyusa izingozi ezithile uma ithathwa nge-gemfibrozil. Ungasebenzisi le mithi nge-gemfibrozil. Zandisa amathuba okuba nobuthi bemisipha noma ukwehluleka kwezinso. Lokhu kungenzeka ngemuva kwamasonto amathathu okwelashwa okuhlangene, noma kungenzeka ngemuva kwezinyanga ezimbalwa. Izibonelo zale mithi zifaka:

• mthombeni
• i-fluvastatin
• umabhebhana
• pitavastatin
• pravastatin
• rosuvastatin
• simvastatin

Futhi, izidakamizwa ezithile ze-cholesterol zinganciphisa imiphumela ye-gemfibrozil. Ukuvimbela lokhu, kufanele uthathe le mithi amahora amabili noma ngaphezulu ngemuva kokuthatha i-gemfibrozil. Izibonelo zale mithi zifaka:

• kucofe
• umabhebhana
• lindokuhle

Izidakamizwa zikashukela

Ukusebenzisa i-gemfibrozil ngemithi ethile yesifo sikashukela kungakhuphula imiphumela yalezo zidakamizwa. Lokhu kuphakamisa ingozi yakho yamazinga kashukela aphansi egazini. Ungasebenzisi le mithi nge-gemfibrozil. Izibonelo zale mithi zifaka:

• umabhebhana

Eminye imishanguzo yesifo sikashukela ingadinga ukunciphisa ukuncipha uma inikezwa nge-gemfibrozil. Lokhu kufaka phakathi:

• i-glyburide
• sphamandla
• glipizide
• nutslinide
• imvuzone
• mthombeni

Isidakamizwa se-Gout

I-Colchicine isetshenziselwa ukwelapha i-gout. Usebenzisa i-gemfibrozil ngalo muthi kuphakamisa ubungozi bakho bokuba yingozi yemisipha ebucayi. Lesi simo singadala ukwehluleka kwezinso noma ukufa. Ungaba sengozini enkulu uma umdala (uneminyaka engama-65 noma ngaphezulu) noma unezinkinga zezinso.

Isidakamizwa se-Hepatitis C

I-Dasabuvir isetshenziselwa ukwelapha i-hepatitis C. Musa ukusebenzisa lesi sidakamizwa nge-gemfibrozil.

Umuthi we-pulmonary arterial hypertension (PAH)

I-Selexipag isetshenziselwa ukwelapha i-PAH. Ungasebenzisi lesi sidakamizwa nge-gemfibrozil.

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zisebenzisana ngokwehlukile kumuntu ngamunye, asikwazi ukuqinisekisa ukuthi lolu lwazi lubandakanya konke ukuxhumana okungenzeka. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala ukhuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nokuhlangana okungenzeka ngayo yonke imishanguzo kadokotela, amavithamini, amakhambi kanye nezithasiselo, kanye nemithi oyithenga uphuza yona.

Izexwayiso zeGemfibrozil

Lesi sidakamizwa siza nezixwayiso eziningana.

Isexwayiso somzimba

I-Gemfibrozil ingadala ukusabela okweqile komzimba. Izimpawu zingafaka:

• inkinga yokuphefumula
• ukuvuvukala komphimbo wakho

Uma uthuthukisa lezi zimpawu, shayela ku-911 noma uye egumbini lezimo eziphuthumayo eliseduze.

Ungaphinde uwuthathe lo muthi uma ngabe uke waba nokungezwani komzimba nawo. Ukuyithatha futhi kungaba yingozi (kungadala ukufa).

Izexwayiso zabantu abanezimo ezithile zempilo

Kubantu abanezinkinga zezinso: IGemfibrozil ingenza isifo sakho sezinso sibe sibi kakhulu. Uma uhluleka izinso, akufanele usebenzise i-gemfibrozil.

Kubantu abanesifo senhliziyo: I-Gemfibrozil ayiboniswanga ukunciphisa ubungozi bokufa ngenxa yesifo senhliziyo. Udokotela wakho angamisa ukusetshenziswa kwakho kwe-gemfibrozil uma kungabangeli ukwehla okukhulu kuma-triglycerides akho.

Izexwayiso kwamanye amaqembu

Kwabesifazane abakhulelwe: IGemfibrozil yisigaba C somuthi wokukhulelwa. Lokho kusho izinto ezimbili:

1. Ukucwaninga ngezilwane kukhombise imiphumela emibi embungwini lapho umama ethatha umuthi.
2. Akuzange kube nezifundo ezanele ezenziwe ebantwini ukuze kuqinisekiswe ukuthi umuthi ungawuthinta kanjani umbungu.

Khuluma nodokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Lesi sidakamizwa kufanele sisetshenziswe kuphela uma inzuzo engaba khona iqinisekisa ubungozi obungaba khona.

Uma ukhulelwa ngenkathi usebenzisa lesi sidakamizwa, shayela udokotela wakho ngokushesha.

Kwabesifazane abancelisayo: IGemfibrozil ingadlula ibisi lwebele futhi ingadala imiphumela emibi enganeni enceliswa ibele. Khuluma nodokotela wakho uma uncelisa ingane yakho ibele. Akufanele uncelise futhi usebenzise lesi sidakamizwa ngasikhathi sinye.

Okwabadala: Izinso zabantu abadala zingase zingasebenzi ngendlela ababevame ngayo. Lokhu kungadala ukuthi umzimba wakho ukwazi ukucubungula izidakamizwa kancane. Ngenxa yalokhu, inani eliphakeme lomuthi lihlala emzimbeni wakho isikhathi eside. Lokhu kwandisa ingozi yemiphumela emibi.

Ungayithatha kanjani i-gemfibrozil

Yonke imithamo engenzeka kanye namafomu ezidakamizwa kungenzeka angafakwa lapha. Umthamo wakho, ifomu lesidakamizwa, nokuthi uwuthatha kangaki umuthi kuzoya ngokuthi:

• iminyaka yakho
• isimo esilashwa
• ubunzima besimo sakho
• ezinye izimo zezokwelapha onazo
• ukuthi usabela kanjani esilinganisweni sokuqala

Amafomu wezidakamizwa namandla

Okujwayelekile: Gemfibrozil

• Ifomu: ithebhulethi yomlomo
• Amandla: 600 mg

Umkhiqizo: I-Lopid

• Ifomu: ithebhulethi yomlomo
• Amandla: 600 mg

Isikali se-cholesterol ephezulu

Isikali sabadala (iminyaka eyi-18-64 iminyaka):

Umthamo ojwayelekile ungama-600 mg kabili ngosuku.

Isilinganiso sengane (iminyaka engu-0-17):

Akuqinisekisiwe ukuthi i-gemfibrozil iphephile futhi iyasebenza ukuze isetshenziswe ezinganeni. Ungayisebenzisi ezinganeni ezingaphansi kweminyaka eyi-18.

Umthamo omkhulu (oneminyaka engama-65 nangaphezulu):

Izinso zabantu abadala zingase zingasebenzi ngendlela ababevame ngayo. Lokhu kungadala ukuthi umzimba wakho ukwazi ukucubungula izidakamizwa kancane. Ngenxa yalokhu, inani eliphakeme lomuthi lihlala emzimbeni wakho isikhathi eside. Lokhu kwandisa ingozi yemiphumela emibi.

Uma unezinkinga zezinso, udokotela wakho angakuqala kumthamo owehlisiwe noma uhlelo oluhlukile lwemithi. Lokhu kungasiza ukugcina amazinga alo muthi ekwakheni kakhulu emzimbeni wakho.

Ukuzikhulula: Inhloso yethu ukukunikeza imininingwane efanelekile futhi yamanje. Kodwa-ke, ngoba izidakamizwa zithinta umuntu ngamunye ngokuhlukile, asikwazi ukuqinisekisa ukuthi lolu hlu lubandakanya yonke imithamo engenzeka. Lolu lwazi aluyithathi indawo yeseluleko sezokwelapha. Hlala ukhuluma nodokotela wakho noma usokhemisi ngemithamo ekufanele.

Thatha njengoba kuqondisiwe

I-Gemfibrozil isetshenziselwa ukwelashwa isikhathi eside. Udokotela wakho anganquma ukumisa i-gemfibrozil ngemuva kwezinyanga ezintathu zokwelashwa uma ungenalo ushintsho olwanele emazingeni akho e-triglyceride.

Lesi sidakamizwa siza nezingozi ezinkulu uma ungathathi njengoba kuchaziwe.

Uma uyeka ukuthatha umuthi ngokungazelelwe noma ungawuthathi nhlobo: Izinga lakho le-triglyceride lingakhuphuka. Uma amazinga akho e-triglyceride ephezulu kakhulu, usengozini enkulu yesifo senhliziyo noma i-pancreatitis.

Uma uphuthelwa imithamo noma ungaphuzi umuthi ngesikhathi: Imithi yakho kungenzeka ingasebenzi kahle noma ingayeka ukusebenza ngokuphelele. Ukuze lo muthi usebenze kahle, inani elithile lidinga ukuba semzimbeni wakho ngaso sonke isikhathi.

Uma uthatha kakhulu: Ungaba namazinga ayingozi omuthi emzimbeni wakho. Izimpawu zokudlula ngokweqile zingabandakanya:

• ukucasuka kwesisu
• ikhanda
• ubuhlungu bemisipha

Uma ucabanga ukuthi uthathe kakhulu lo muthi, shayela udokotela wakho noma funa ukuholwa yi-American Association of Poison Control Centers ku-1-800-222-1222 noma ngethuluzi labo eliku-inthanethi. Kepha uma izimpawu zakho zinzima, shayela ku-911 noma uye egumbini lezimo eziphuthumayo eliseduze ngokushesha.

Okufanele ukwenze uma uphuthelwa umthamo: Thatha umthamo wakho ngokushesha nje lapho ukhumbula. Kepha uma ukhumbula amahora ambalwa ngaphambi komthamo wakho olandelayo ohleliwe, thatha umthamo owodwa kuphela. Ungalokothi uzame ukuthola ngokuthatha amanani amabili ngasikhathi sinye. Lokhu kungaholela emiphumeleni emibi eyingozi.

Ungasho kanjani ukuthi umuthi uyasebenza: Kufanele ube nokwehla kuma-triglycerides akho kanye nokwanda kwamazinga akho e-HDL. Ungase ungazizwa uhlukile lapho uthatha lo muthi. Udokotela wakho uzoqapha amazinga akho e-cholesterol ukuqinisekisa ukuthi umuthi uyakusebenzela.

Ukucatshangelwa okubalulekile kokuthatha i-gemfibrozil

Gcina lokhu kucatshangelwa engqondweni uma udokotela wakho ekunika i-gemfibrozil.

Jikelele

• Lesi sidakamizwa kufanele sithathwe ngaphambi kokudla. Thatha imizuzu engama-30 ngaphambi kokudla kwakho kwasekuseni nakusihlwa.
• Musa ukusika noma ukuchoboza ithebhulethi.

Isitoreji

• Gcina i-gemfibrozil ekamelweni lokushisa eliphakathi kuka-68 ° F no-77 ° F (20 ° C no-25 ° C).
• Gcina lesi sidakamizwa kude nokukhanya.
• Ungawugcini lo muthi ezindaweni ezinomswakama noma ezinomswakama, njengezindlu zangasese.

Ukugcwalisa kabusha

Imibhalo kadokotela yalomuthi iyagcwaliseka. Akudingeki ukuthi unikezwe umuthi omusha kadokotela ukuze ugcwaliswe futhi lo muthi. Udokotela wakho uzobhala inani lama-refill eligunyazwe kudokotela wakho.

Ukuvakasha

Lapho uhamba nemithi yakho:

• Ngaso sonke isikhathi phatha imithi yakho. Lapho undiza, ungalokothi uwufake esikhwameni esihloliwe. Yigcine esikhwameni sakho sokuthwala.
• Ungakhathazeki ngemishini ye-X-ray yesikhumulo sezindiza. Abakwazi ukulimaza umuthi wakho.
• Ungadinga ukukhombisa abasebenzi bezindiza ilebula lekhemisi lemithi yakho. Ngaso sonke isikhathi phatha isitsha sokuqala esinelebula kadokotela.
• Ungafaki lo muthi egumbini legilavu ​​lemoto yakho noma uwushiye emotweni. Qinisekisa ukugwema ukwenza lokhu lapho isimo sezulu sishisa kakhulu noma sibanda kakhulu.

Ukuqapha komtholampilo

Udokotela wakho uzoqapha amazinga akho e-triglyceride ngenkathi uthatha lesi sidakamizwa. Bangabheka amazinga akho e-triglyceride njalo ezinyangeni ezi-3 kuye kwezi-12 ukuqinisekisa ukuthi lo muthi uyasebenza.

Ukudla kwakho

Ngaphezu kokusebenzisa i-gemfibrozil, ukudla okuhle kubalulekile ukukusiza ukulawula amazinga akho e-triglyceride. Ukwehla kwesisindo kungasiza futhi ekubuyiseleni amazinga e-triglyceride ebangeni elijwayelekile. Khuluma nodokotela wakho noma isazi sokudla ukuze uthole olunye ulwazi.

Ingabe zikhona ezinye izindlela?

Kuneminye imithi etholakalayo yokwelapha isimo sakho. Ezinye zingakulungela kangcono kunabanye. Khuluma nodokotela wakho ngezinye izinketho zezidakamizwa ezingakusebenzela.

Ukuzikhulula: I-Healthline yenze yonke imizamo yokuqinisekisa ukuthi lonke ulwazi luyiqiniso, luphelele futhi lusesikhathini. Kodwa-ke, le ndatshana akufanele isetshenziswe njengokungena esikhundleni solwazi nobungoti bochwepheshe bezokunakekelwa kwezempilo onelayisense. Kufanele uhlale uthintana nodokotela wakho noma omunye uchwepheshe wezokunakekelwa kwempilo ngaphambi kokuthatha noma imuphi umuthi. Imininingwane yezidakamizwa equkethwe lapha ingashintsha futhi ayihloselwe ukumboza konke ukusetshenziswa okungaba khona, izinkomba, izixwayiso, izexwayiso, ukuxhumana kwezidakamizwa, ukungezwani komzimba, noma imiphumela emibi. Ukungabikho kwezixwayiso noma olunye ulwazi lomuthi othile awukhombisi ukuthi inhlanganisela yezidakamizwa noma yezidakamizwa iphephile, iyasebenza, noma ilungele zonke iziguli noma konke ukusetshenziswa okuthile.