Insulinoma

-Delile

• Ziyini Izimpawu ze-Insulinoma?
• Yini Ebangela i-Insulinoma?
• Ngubani Osengozini Ye-Insulinoma?
• I-Insulinoma Ihlonza Kanjani?
• Iphathwa Kanjani I-Insulinoma?
• Uyini Umbono Wesikhathi Eside Wabantu Abane-Insulinoma?
• I-Insulinoma Ingavinjelwa Kanjani?

Kuyini i-Insulinoma?

I-insulinoma yisimila esincane kumanyikwe esikhiqiza inani elingaphezulu kwe-insulin. Ezimweni eziningi, isimila asiwona umdlavuza. Iningi lama-insulinoma lingaphansi kwamasentimitha amabili ububanzi.

Ama-pancreas isitho se-endocrine esisemuva kwesisu sakho. Omunye wemisebenzi yawo ukukhiqiza ama-hormone alawula izinga likashukela egazini lakho, njenge-insulin. Ngokuvamile, amanyikwe ayayeka ukudala i-insulin lapho ushukela wegazi lakho wehla kakhulu. Lokhu kuvumela amazinga kashukela egazini lakho ukuthi abuyele kokujwayelekile. Lapho i-insulinoma yakha amanyikwe akho, noma kunjalo, izoqhubeka nokukhiqiza i-insulin, noma ngabe ushukela wegazi lakho uphansi kakhulu. Lokhu kungaholela ku-hypoglycemia enamandla, noma ushukela wegazi ophansi. I-Hypoglycemia yisimo esiyingozi esingadala ukufiphala, ikhanda elikhanyayo, nokuquleka. Kungasongela nokuphila.

I-insulinoma ngokuvamile idinga ukususwa ngokuhlinzwa. Lapho nje isimila sisusiwe, ukululama okuphelele kungenzeka kakhulu.

Ziyini Izimpawu ze-Insulinoma?

Abantu abane-insulinomas abanazo izimpawu ezibonakalayo ngaso sonke isikhathi. Lapho izimpawu zenzeka, zingahluka ngokuya ngobukhulu besimo.

Izimpawu ezimnene zifaka:

• ukubona kabili noma ukufiphala kwamehlo
• ukudideka
• ukukhathazeka nokucasuka
• isiyezi
• ukushintsha kwemizwelo
• ubuthakathaka
• ukujuluka
• indlala
• ukuthuthumela
• ukuzuza kwesisindo ngokungazelelwe

Izimpawu ezinzima ze-insulinoma zingathinta ubuchopho. Zingathinta nezindlala ze-adrenal, ezilawula ukuphendula kwengcindezi nokushaya kwenhliziyo. Kwesinye isikhathi, izimpawu zibukeka zifana nalezo zesifo sokuwa, okuyisifo sezinzwa esibanga ukuquleka. Izimpawu ezibonakala ezimweni ezimbi kakhulu ze-insulinoma zingafaka:

• ukudlikizela noma ukuquleka
• ukushaya kwenhliziyo okusheshayo (okungaphezu kokushaya okungama-95 ngomzuzu)
• ubunzima bokugxila
• ukulahlekelwa ukwazi noma ikhoma

Kwezinye izimo, ama-insulinomas angakhula futhi asabalale aye kwezinye izingxenye zomzimba. Uma lokhu kwenzeka, ungathola lezi zimpawu ezilandelayo:

• ubuhlungu besisu
• ukuhlungu obusemhlane
• isifo sohudo
• i-jaundice, noma ukuphuzi kwesikhumba namehlo

Yini Ebangela i-Insulinoma?

Odokotela abazi kahle ukuthi kungani abantu bethola ama-insulinomas. Izicubu zivame ukuvela ngaphandle kwesixwayiso.

Uma udla ukudla, amanyikwe enza i-insulin. I-insulin yihomoni esiza umzimba wakho ukugcina ushukela ekudleni kwakho. Lapho ushukela usumunciwe, amanyikwe ayayeka ukukhiqiza i-insulin. Le nqubo ivame ukugcina amazinga kashukela egazini azinzile. Kodwa-ke, kungaphazamiseka lapho i-insulinoma ikhula. Isimila siyaqhubeka nokukhiqiza i-insulin noma ngabe ushukela wegazi lakho wehla kakhulu. Lokhu kungaholela ku-hypoglycemia, isimo esibi esibonakala ngamazinga kashukela egazi aphansi.

Ngubani Osengozini Ye-Insulinoma?

Ama-insulinomas ayivelakancane. Iningi lincane futhi likala ngaphansi kwamasentimitha amabili ububanzi. Amaphesenti ayi-10 kuphela alezi zicubu anomdlavuza. Izicubu zomdlavuza zivame ukwenzeka kaningi kubantu abanezinhlobo eziningi ze-endocrine neoplasia 1. Lesi yisifo esizuzwe njengefa esidala izicubu kwesinye sezindlala zehomoni. Ingozi ye-insulinoma nayo ibonakala iphezulu kulabo abane-von Hippel-Lindau syndrome. Lesi simo esizuzwe njengefa senza izicubu nama-cysts akheke emzimbeni wonke.

Ama-insulinulin nawo athanda ukuthinta abesifazane kakhulu kunabesilisa. Zivame ukukhula kubantu abaphakathi kweminyaka engama-40 nengama-60.

I-Insulinoma Ihlonza Kanjani?

Udokotela wakho uzokwenza ukuhlolwa kwegazi ukuze ahlole ushukela wegazi lakho namazinga e-insulin. Izinga likashukela egazini eliphansi nelizinga eliphezulu le-insulin likhombisa ukuba khona kwe-insulinoma.

Isivivinyo singahlola nokuthi:

• amaprotheni avimba ukukhiqizwa kwe-insulin
• imithi ebangela amanyikwe ukuthi akhulule i-insulin eyengeziwe
• amanye ama-hormone athinta ukukhiqizwa kwe-insulin

Udokotela wakho angalawula ukushesha kwamahora angama-72 uma ukuhlolwa kwegazi kukhombisa ukuthi une-insulinoma. Uzohlala esibhedlela ngenkathi uzila ukudla ukuze udokotela wakho akwazi ukuqapha amazinga kashukela egazini lakho. Bazokala amazinga kashukela egazini lakho njalo emahoreni ayisithupha okungenani. Ngeke ukwazi ukudla noma ukuphuza noma yini ngaphandle kwamanzi ngesikhathi sokuzila. Kungenzeka ube namazinga kashukela egazini aphansi kakhulu kungakapheli amahora angama-48 ukuqala ukushesha uma une-insulinoma.

Udokotela wakho angenza izivivinyo eziningi ukuqinisekisa ukuxilongwa, kufaka phakathi i-MRI noma i-CT scan. Lezi zivivinyo ze-imaging zisiza udokotela wakho ukuthi anqume indawo nobukhulu be-insulinoma.

I-endoscopic ultrasound ingasetshenziswa uma isimila singatholakali kusetshenziswa i-CT noma i-MRI scan. Ngesikhathi se-endoscopic ultrasound, udokotela wakho ufaka ithubhu ende, eguquguqukayo emlonyeni wakho nangaphansi kwesisu namathumbu amancane. Ishubhu line-probe ye-ultrasound, ekhipha amaza emisindo akhiqiza izithombe ezinemininingwane yamanyikwe akho. Lapho nje i-insulinoma isikhona, udokotela wakho uzothatha isampula elincane lezicubu ukuze azihlaziye. Lokhu kungasetshenziselwa ukunquma ukuthi isimila sinomdlavuza yini.

Iphathwa Kanjani I-Insulinoma?

Ukwelashwa okungcono kakhulu kwe-insulinoma ukususwa kokuhlinzwa kwesimila. Ingxenye encane yamanyikwe nayo ingasuswa uma kuneqhubu elingaphezu kwelilodwa. Lokhu kwelapha lesi simo.

Kunezinhlobo ezahlukahlukene zokuhlinzwa ezingenziwa ukukhipha i-insulinoma. Indawo nenombolo yamathumba kunquma ukuthi yikuphi ukuhlinzwa okuzosetshenziswa.

Ukuhlinzwa nge-laparoscopic kuyindlela ekhethwayo uma kukhona isimila esisodwa kuphela se-pancreatic. Le yinqubo enobungozi obuncane, obuncane bokuhlasela. Ngesikhathi sokuhlinzwa kwe-laparoscopic, udokotela wakho ohlinzayo wenza ukusikeka okuncane esiswini sakho bese ufaka i-laparoscope ngokusebenzisa ukusikeka. I-laparoscope iyishubhu ende, ezacile enesibani esinamandla amakhulu nekhamera enokucaca okuphezulu ngaphambili. Ikhamera izobonisa izithombe esikrinini, ivumele udokotela ohlinzayo ukuthi abone ngaphakathi kwesisu sakho futhi aqondise izinsimbi. Lapho i-insulinoma itholakala, izosuswa.

Ingxenye yamanyikwe ingadinga ukususwa uma kukhona ama-insulinomas amaningi. Kwesinye isikhathi, ingxenye yesisu noma yesibindi nayo ingasuswa.

Ezimweni ezingavamile, ukususa i-insulinoma ngeke kuselaphe lesi simo. Lokhu kuvame ukuba yiqiniso lapho izimila zinomdlavuza. Ukwelashwa kwama-insulinomas anomdlavuza kufaka:

• i-radiofrequency ablation, esebenzisa amagagasi omsakazo ukubulala amangqamuzana anomdlavuza emzimbeni
• i-cryotherapy, ehilela ukusetshenziswa kwamakhaza kakhulu ukubhubhisa amangqamuzana anomdlavuza
• i-chemotherapy, okuwuhlobo olunolaka lokwelashwa ngamakhemikhali okusiza ukuqeda amangqamuzana anomdlavuza

Udokotela wakho futhi angakunikeza imithi yokulawula amazinga kashukela egazini uma ukuhlinzwa kungasebenzi.

Uyini Umbono Wesikhathi Eside Wabantu Abane-Insulinoma?

Umbono wesikhathi eside wabantu abane-insulinoma muhle kakhulu uma kususwa isimila. Ngemuva kokuhlinzwa, abantu abaningi balulama ngokuphelele ngaphandle kwezinkinga. Kodwa-ke, i-insulinoma ingabuya ngokuzayo. Ukuphindaphinda kuvame kakhulu kubantu abanezicubu eziningi.

Inani elincane kakhulu labantu lingaba nesifo sikashukela ngemuva kokuhlinzwa. Lokhu kuvame ukwenzeka kuphela lapho kususwe wonke amanyikwe noma ingxenye enkulu yamanyikwe.

Izinkinga zingenzeka kakhulu kubantu abane-insulinomas yomdlavuza. Lokhu kuyiqiniso ikakhulukazi lapho izicubu sezisakazekele kwezinye izitho. Udokotela ohlinzayo kungenzeka angakwazi ukususa wonke amathumba ngokuphelele. Kulokhu, kuzodingeka ukwelashwa okuningi nokunakekelwa okulandelwayo. Ngenhlanhla, inani elincane kuphela lama-insulinoma elinomdlavuza.

I-Insulinoma Ingavinjelwa Kanjani?

Odokotela abazi ukuthi kungani ama-insulinomas akha, ngakho-ke ayikho indlela eyaziwayo yokuwavimbela. Kodwa-ke, unganciphisa ubungozi bokuthuthukisa i-hypoglycemia ngokuzivocavoca njalo nokugcina ukudla okunempilo. Lokhu kudla kufanele kube nezithelo, imifino, namaprotheni anciphile. Futhi ungagcina amanyikwe akho enempilo ngokudla inyama ebomvu encane nokuyeka ukubhema uma ubhema.