I-Lupus Nephritis

-Delile

• Ziyini izimpawu ze-lupus nephritis?
• Ukuhlonza i-lupus nephritis
• Ukuhlolwa kwegazi
• Ukuqoqwa komchamo wamahora angama-24
• Ukuhlolwa komchamo
• Ukuhlolwa kokuvunyelwa kwe-Iothalamate
• Ukuhlolwa kwezinso
• Izigaba ze-lupus nephritis
• Izinketho zokwelashwa kwe-lupus nephritis
• Izinkinga ze-lupus nephritis
• Umbono wesikhathi eside wabantu abane-lupus nephritis

Iyini i-lupus nephritis?

I-lupic erythematosus (SLE) ejwayelekile ibizwa ngokuthi i-lupus. Kuyisimo lapho amasosha akho omzimba aqala khona ukuhlasela izindawo ezahlukahlukene zomzimba wakho.

I-Lupus nephritis ingenye yezinkinga ezinkulu kakhulu ze-lupus. Kwenzeka lapho i-SLE ibangela ukuthi amasosha omzimba wakho ahlasele izinso zakho - ikakhulukazi, izingxenye zezinso zakho ezihlunga igazi lakho ngemikhiqizo kadoti.

Ziyini izimpawu ze-lupus nephritis?

Izimpawu zeLupus nephritis ziyefana nezinye izifo zezinso. Kubandakanya:

• umchamo omnyama
• igazi emchameni wakho
• umchamo onamagwebu
• ukuchama kaningi, ikakhulukazi ebusuku
• ukukhukhumala ezinyaweni, emaqakaleni nasemilenzeni okuya ngokuya kuba nzima phakathi nosuku
• ukuthola isisindo
• umfutho wegazi ophakeme

Ukuhlonza i-lupus nephritis

Esinye sezibonakaliso zokuqala ze-lupus nephritis igazi egazini lakho noma umchamo we-foamy ngokweqile. Umfutho wegazi ophakeme nokuvuvukala ezinyaweni zakho nakho kungakhombisa i-lupus nephritis. Ukuhlolwa okuzosiza udokotela wakho ukuthi axilongeke kufaka okulandelayo:

Ukuhlolwa kwegazi

Udokotela wakho uzobheka amazinga aphakeme wemikhiqizo kadoti, njenge-creatinine ne-urea. Imvamisa, izinso ziyayihlunga le mikhiqizo.

Ukuqoqwa komchamo wamahora angama-24

Lokhu kuhlolwa kukala ikhono lezinso ngokukhetha ukuhlunga imfucuza. Inquma ukuthi mangakanani amaprotheni avela emchameni ngaphezu kwamahora angama-24.

Ukuhlolwa komchamo

Ukuhlolwa komchamo kukala ukusebenza kwezinso. Bakhomba amazinga we:

• amaprotheni
• amangqamuzana abomvu egazi
• amaseli egazi amhlophe

Ukuhlolwa kokuvunyelwa kwe-Iothalamate

Lokhu kuhlolwa kusebenzisa udayi wokuqhathanisa ukubona ukuthi izinso zakho zihlunga kahle yini.

Iothalamate enemisebe ijojowe egazini lakho. Udokotela wakho uzobe esehlola ukuthi ukhishwa ngokushesha kangakanani emchameni wakho. Bangase futhi bahlole ngokuqondile ukuthi ishiya igazi lakho ngokushesha kangakanani. Lokhu kuthathwa njengokuhlolwa okunembe kakhulu kwejubane lokuhlunga izinso.

Ukuhlolwa kwezinso

Ama-Biopsies ayindlela enembe kunazo zonke futhi ehlasela kakhulu ukuthola isifo sezinso. Udokotela wakho uzofaka inaliti ende esiswini sakho nasesinso sakho. Bazothatha isampula lezicubu zezinso ukuze zihlaziyelwe izimpawu zomonakalo.

Izigaba ze-lupus nephritis

Ngemuva kokuxilongwa, udokotela wakho uzonquma ubukhulu bomonakalo wakho wezinso.

I-World Health Organisation (i-WHO) yasungula uhlelo lokuhlukanisa izigaba ezinhlanu ezihlukene ze-lupus nephritis ngo-1964. Amazinga amasha okuhlela asungulwa ngo-2003 yi-International Society of Nephrology kanye ne-Renal Pathology Society. Ukuhlukaniswa okusha kususe isigaba sokuqala I esasingenabo ubufakazi besifo futhi sangeza isigaba sesithupha:

• Ikilasi I: I-mesangial lupus nephritis encane
• Isigaba II: I-Mesangial proliferative lupus nephritis
• Isigaba III: I-Focal lupus nephritis (esebenzayo futhi engapheli, eyandayo ne-sclerosing)
• Isigaba IV: Ukusabalalisa i-lupus nephritis (esebenzayo futhi engapheli, eyandayo ne-sclerosing, esegmental neyomhlaba jikelele)
• Isigaba V: Ulwelwesi lwe-lupus nephritis
• Isigaba VI: Advanced sclerosis lupus nephritis

Izinketho zokwelashwa kwe-lupus nephritis

Alikho ikhambi le-lupus nephritis. Inhloso yokwelashwa ukugcina inkinga ingabi yimbi kakhulu. Ukumisa ukulimala kwezinso kusenesikhathi kungavimbela isidingo sokufakelwa kwezinso.

Ukwelashwa nakho kunganikeza ukukhululeka kwizimpawu ze-lupus.

Ukwelashwa okuvamile kufaka:

• ukunciphisa ukudla kwakho kwamaprotheni nosawoti
• uthatha imishanguzo yegazi
• usebenzisa i-steroids efana ne-prednisone (i-Rayos) ukunciphisa ukuvuvukala nokuvuvukala
• uthatha imishanguzo ukucindezela amasosha akho omzimba njenge-cyclophosphamide noma i-mycophenolate-mofetil (CellCept)

Kucatshangelwa ngokukhethekile izingane noma abesifazane abakhulelwe.

Ukulimala okukhulu kwezinso kungadinga ukwelashwa okwengeziwe.

Izinkinga ze-lupus nephritis

Inkinga ebucayi kakhulu ehlotshaniswa ne-lupus nephritis ukwehluleka kwezinso. Abantu abanokwehluleka kwezinso bazodinga i-dialysis noma ukufakelwa izinso.

I-Dialysis imvamisa iyindlela yokuqala yokwelashwa, kepha ngeke isebenze unomphela. Iziguli eziningi ze-dialysis ekugcineni zizodinga ukufakelwa. Kodwa-ke, kungathatha izinyanga noma iminyaka ngaphambi kokuba isitho sabanikeli sitholakale.

Umbono wesikhathi eside wabantu abane-lupus nephritis

Umbono wabantu abane-lupus nephritis uyahluka. Iningi labantu libona kuphela izimpawu zesikhashana. Ukulimala kwabo kwezinso kungaqashelwa kuphela ngesikhathi sokuhlolwa komchamo.

Uma unezimpawu ezibucayi kakhulu ze-nephritis, usengozini enkulu yokulahlekelwa umsebenzi wezinso. Ukwelashwa kungasetshenziselwa ukunciphisa inkambo ye-nephritis, kepha akuphumeleli ngaso sonke isikhathi. Khuluma nodokotela wakho mayelana nokuthi yikuphi ukwelashwa okulungele wena.