Izimbangela eziyinhloko zama-Macroplatelets nokuthi ungazibona kanjani

-Delile

• Izimbangela eziyinhloko zama-Macroplatelets
• Ukukhonjwa kwenziwa kanjani

Ama-Macroplates, abizwa nangokuthi ama-platelet amakhulu, ahambelana nama-platelet osayizi nevolumu enkulu kunosayizi ojwayelekile weplatelet, angaba ngu-3 mm futhi anenani le-7.0 fl ngokwesilinganiso. Lawa ma-platelet amakhulu ngokuvamile akhombisa ukuguqulwa kwinqubo yokusebenza kweplatelet nenqubo yokukhiqiza, okungenzeka kube ngenxa yezinkinga zenhliziyo, isifo sikashukela noma izimo ze-hematological, njenge-leukemia kanye ne-myeloproliferative syndromes.

Ukuhlolwa kukasayizi weplatelet kwenziwa ngokubheka i-smear yegazi ngaphansi kwesibonakhulu kanye nomphumela wesibalo segazi esiphelele, okufanele sibe nenani nevolumu yama-platelet.

Izimbangela eziyinhloko zama-Macroplatelets

Ukuba khona kwama-macroplates egazini kukhombisa ukugqugquzela inqubo yokwenza iplatelet isebenze, engadalwa yizimo eziningana, lezo eziyinhloko:

• Hyperthyroidism;
• Izifo ze-Myeloproliferative, njenge-thrombocythemia ebalulekile, i-myelofibrosis ne-polycythemia vera;
• I-purpura ye-Idiopathic thrombocytopenic;
• Isifo Sikashukela;
• I-infarction ye-myocardial enamandla;
• Umdlavuza wegazi;
• I-Myelodysplastic Syndrome;
• Isifo sikaBernard-Soulier.

Ama-platelet amakhulu kunokujwayelekile anezinga eliphakeme lomsebenzi namandla okungenzeka asebenze, ngaphezu kokuthanda izinqubo ze-thrombotic, ngoba anokukhululeka okukhulu kokuhlanganiswa kweplatelet nokwakheka kwe-thrombus, okungaba kubi impela. Ngakho-ke, kubalulekile ukuthi kwenziwe izivivinyo ukwazi inani lamaplatelet ajikelezayo nezimpawu zawo. Uma kutholakala izinguquko, kubalulekile ukukhomba imbangela yama-macroplates ukuze kuqale ukwelashwa okufanele kakhulu.

Ukukhonjwa kwenziwa kanjani

Ukuhlonza ama-macroplates kwenziwa ngokuhlolwa kwegazi, ikakhulukazi inani eliphelele legazi, lapho kuhlolisiswa khona zonke izingxenye zegazi, kufaka phakathi amaplatelets. Ukuhlolwa kweplatelet kwenziwa kokubili ngobuningi nangokwekhwalithi. Okusho ukuthi, kubhekwa inani lamaplatelet ajikelezayo, inani lalo elijwayelekile liphakathi kuka-150000 no-450000 platelets / µL, engahluka phakathi kwamalabhorethri, kanye nezici zamaplatelet.

Lezi zici zibonwa zombili ngemicroscopic futhi ngokusebenzisa i-Average Platelet Volume, noma i-MPV, okuyipharamitha yelabhorethri ekhombisa ivolumu yama-platelet, ngakho-ke, kungenzeka wazi ukuthi makhulu kunokujwayelekile nezinga lomsebenzi weplatelet. Imvamisa, lapho i-MPV iphakama, amaplatelet ayanda futhi kwehla inani eliphelele lama-platelet ajikeleza egazini, lokhu kungenxa yokuthi ama-platelet akhiqizwa futhi abhujiswe ngokushesha. Yize kuyipharamitha ebalulekile yokuqinisekisa ukushintshwa kweplatelet, amanani we-MPV kunzima ukuwamisa futhi angahle aphazanyiswe ezinye izinto.

Bona okuningi ngama-platelet.