Ukuhlolwa Kwesikhathi Esincane seThromboplastin (PTT)

-Delile

• Kungani ngidinga ukuhlolwa kwe-PTT?
• Ngilungiselela kanjani ukuhlolwa kwe-PTT?
• Ziyini izingozi ezihambisana nokuhlolwa kwe-PTT?
• Kwenziwa kanjani ukuhlolwa kwe-PTT?
• Isho ukuthini imiphumela?
• Imiphumela ejwayelekile yokuhlolwa kwe-PTT
• Imiphumela yokuhlolwa engajwayelekile ye-PTT

Yini isivivinyo se-thromboplastin time (PTT) esinqunyelwe?

Ukuhlolwa kwe-thromboplastin time (PTT) okuyingxenye ukuhlolwa kwegazi okusiza odokotela ukuhlola amandla omzimba wakho wokwenza amahlule egazi.

Ukopha kubangela uchungechunge lokuphendula okwaziwa ngokuthi i-coagulation cascade. Ukujiya yinqubo esetshenziswa umzimba wakho ukuyeka ukopha. Amaseli abizwa ngama- platelet akha ipulaki yokumboza izicubu ezilimele. Lapho-ke izinto ezijiyisayo zomzimba wakho ziyahlangana zenze ihlwili legazi. Izinga eliphansi lezinto ezijiyayo lingavimbela amahlwili ekubunjweni. Ukushoda kwezinto ezijiyisayo kungaholela ezimpawu ezifana nokopha ngokweqile, ukuphuma kwamakhala okuqhubekayo, nokulimala okulula.

Ukuhlola amakhono okuvimba igazi omzimba wakho, ilabhorethri iqoqa isampula yegazi lakho esitsheni bese ingeza amakhemikhali azokwenza igazi lakho lijiye. Isivivinyo silinganisa ukuthi kuthatha amasekhondi amangaki ukuthi i-clot yakheke.

Lokhu kuhlolwa kwesinye isikhathi kubizwa ngokuthi yisivivinyo se-thromboplastin time (APTT) esenziwe sasebenza.

Kungani ngidinga ukuhlolwa kwe-PTT?

Udokotela wakho angayalela ukuhlolwa kwe-PTT ukuphenya imbangela yokopha isikhathi eside noma ngokweqile. Izimpawu ezingashukumisela udokotela wakho uku-oda lokhu kuhlolwa zifaka:

• ukopha kaningi noma okusindayo
• izikhathi ezinzima noma ezinde zokuya esikhathini
• igazi emchameni
• amalunga avuvukile futhi abuhlungu (abangelwa ukopha ezindaweni zakho ezihlangene)
• ukulinyazwa okulula

Ukuhlolwa kwe-PTT akukwazi ukuxilonga isimo esithile. Kepha kuyasiza udokotela wakho ukuthi afunde ukuthi izinto zakho zokuvala igazi zintula yini. Uma imiphumela yakho yokuhlolwa ingavamile, udokotela wakho mhlawumbe uzodinga uku-oda ukuhlolwa okwengeziwe ukuze abone ukuthi isiphi isici umzimba wakho ongasikhiqizi.

Udokotela wakho futhi angasebenzisa lesi sivivinyo ukuqapha isimo sakho lapho uthatha i-heparin yegazi elincanyana.

Ngilungiselela kanjani ukuhlolwa kwe-PTT?

Imithi eminingi ingathinta imiphumela yokuhlolwa kwe-PTT. Lokhu kufaka phakathi:

• i-heparin
• warfarin
• i-aspirin
• ama-antihistamine
• uvithamini C
• i-chlorpromazine

Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo. Ungadinga ukuyeka ukuzithatha ngaphambi kokuhlolwa.

Ziyini izingozi ezihambisana nokuhlolwa kwe-PTT?

Njenganoma yikuphi ukuhlolwa kwegazi, kunengozi encane yokulimala, ukuphuma kwegazi, noma ukutheleleka endaweni yokubhoboza. Ezimweni ezingavamile, umthambo wakho ungavuvukala ngemuva kokudonswa kwegazi. Lesi simo saziwa ngokuthi i-phlebitis. Ukufaka i-compress efudumele izikhathi eziningana ngosuku kungelapha i-phlebitis.

Ukopha okuqhubekayo kungaba yinkinga uma unenkinga yokopha noma uthatha imishanguzo yokuncipha igazi, njenge-warfarin noma i-aspirin.

Kwenziwa kanjani ukuhlolwa kwe-PTT?

Ukwenza isivivinyo, i-phlebotomist noma umhlengikazi uthatha isampula yegazi engalweni yakho. Bahlanza isiza nge-swab yotshwala bese befaka inaliti emthanjeni wakho. Ishubhu elihlanganiswe nenaliti liqoqa igazi. Ngemuva kokuqoqa igazi elanele, basusa inaliti bese bemboza indawo yokubhoboza ngephedi ye-gauze.

Uchwepheshe waselebhu unezela amakhemikhali kulesi sampula segazi futhi alinganise inani lamasekhondi alithathayo ukuze isampula ligodle.

Isho ukuthini imiphumela?

Imiphumela ejwayelekile yokuhlolwa kwe-PTT

Imiphumela yokuhlolwa kwe-PTT ilinganiswa ngemizuzwana. Imiphumela ejwayelekile yimizuzwana engama-25 kuye kwengama-35. Lokhu kusho ukuthi kuthathe isampula yegazi lakho imizuzwana engama-25 kuya kwengama-35 ukumisa ngemuva kokungeza amakhemikhali.

Izindinganiso eziqondile zemiphumela ejwayelekile zingahluka ngokuya ngodokotela wakho kanye nelebhu, ngakho-ke buza udokotela wakho uma kukhona okukukhathazayo.

Imiphumela yokuhlolwa engajwayelekile ye-PTT

Khumbula ukuthi umphumela we-PTT ongajwayelekile awutholi noma yisiphi isifo esithile. Inikeza ukuqonda kuphela ngesikhathi okusithatha ukuze igazi lakho ligodle. Izifo nezimo eziningi kungadala imiphumela engajwayelekile ye-PTT.

Umphumela wesikhathi eside we-PTT ungabangelwa:

• izimo zokuzala, njengokukhulelwa kwakamuva, ukukhulelwa kwamanje, noma ukukhulelwa kwesisu muva nje
• hemophilia A noma B
• ukushoda kwezinto eziqinisa igazi
• Isifo i-von Willebrand (ukuphazamiseka okubanga ukujiya kwegazi okungavamile)
• kusatshalaliswa i-intravascular coagulation (isifo lapho amaprotheni abhekene nokuqina kwegazi asebenza ngokungajwayelekile)
• i-hypofibrinogenemia (ukuntuleka kwegazi elijiyisayo i-fibrinogen)
• imishanguzo ethile, efana ne-heparin yegazi ne-warfarin
• izingqinamba zokudla okunempilo, njengokushoda kukavithamini K kanye ne-malabsorption
• amasosha omzimba, kufaka phakathi amasosha omzimba we-cardiolipin
• i-lupus anticoagulants
• i-leukemia
• isifo sesibindi

Ububanzi obuningi bezimbangela zemiphumela engajwayelekile kusho ukuthi lokhu kuhlolwa kukodwa akwanele ukucacisa ukuthi unasiphi isimo. Umphumela ongajwayelekile cishe uzoshukumisela udokotela wakho uku-oda ezinye izivivinyo.