I-Pyrimethamine (Daraprim)

-Delile

• Intengo
• Izinkomba
• Isetshenziswa kanjani
• Okuqhamuka uma udla imishanguzo
• Izimo

IDaraprim ngumuthi olwa nomalaleveva osebenzisa i-pyrimethamine njengesithako esisebenzayo, esikwazi ukuvimbela ukukhiqizwa kwama-enzyme yi-protozoan ebhekele umalaleveva, ngaleyo ndlela yelapha lesi sifo.

I-Daraprim ingathengwa emakhemisi ajwayelekile anencwadi kadokotela ngesimo samabhokisi aqukethe amaphilisi ayi-100 we-25 mg.

Intengo

Intengo yeDaraprim icishe ibe yi-7 reais, kepha inani lingahluka ngokuya ngendawo lapho kuthengwa khona umuthi.

Izinkomba

I-Daraprim ikhonjisiwe ekuvikeleni nasekwelapheni umalaleveva, kanye neminye imithi. Ngaphezu kwalokho, iDaraprim ingasetshenziselwa ukwelapha iToxoplasmosis, ngokusho kukadokotela.

Isetshenziswa kanjani

Ungayisebenzisa kanjani iDaraprim iyahluka ngokuya ngenhloso yokwelashwa kanye neminyaka yesiguli, ngeziqondiso ezijwayelekile ezibandakanya:

Ukuvimbela umalaleveva

• Abantu abadala nezingane ezingaphezu kweminyaka eyi-10: 1 ithebhulethi ngesonto;
• Izingane ezineminyaka engu-5 kuya kwengu-10 ubudala: ½ ithebhulethi ngesonto;
• Izingane ezingaphansi kweminyaka engu-5: ¼ ithebhulethi ngesonto.

Ukwelashwa kwe-Malaria

• Abantu abadala nezingane ezingaphezu kweminyaka eyi-14: Amaphilisi ama-2 kuye kwayi-3 kanye ne-1000 mg kuya ku-1500 mg ye-sulfadiazine kumthamo owodwa;
• Izingane ezineminyaka engu-9 kuya kwengu-14 ubudala: Amaphilisi ama-2 kanye ne-1000 mg ye-sulfadiazine kumthamo owodwa;
• Izingane ezineminyaka engu-4 kuya kwengu-8 ubudala: 1 ithebhulethi kanye ne-1000 mg ye-sulfadiazine kumthamo owodwa;
• Izingane ezingaphansi kweminyaka engu-4: ½ ithebhulethi kanye ne-1000 mg ye-sulfadiazine kumthamo owodwa.

Okuqhamuka uma udla imishanguzo

Imiphumela emibi kakhulu ye-Daraprim ifaka ukungezwani kwesikhumba, ukushaya kwenhliziyo, isicanucanu, amajaqamba, isifo sohudo, ukungathandi ukudla, igazi emchameni kanye nezinguquko ekuhlolweni kwegazi.

Izimo

I-Daraprim iyaphikiswa ezigulini ezine-megaloblastic anemia yesibili ngenxa yokushoda kwe-folate noma i-hypersensitivity to pyrimethamine noma yiziphi izingxenye zefomula.