Yini i-prolactinoma, izimpawu nokuthi kwenziwa kanjani ukwelashwa

-Delile

• Izimpawu ze-Prolactinoma
• Ukuxilongwa kwenziwa kanjani
• Ukwelashwa kwe-prolactinoma

I-Prolactinoma iyisigaxa esinobungozi esisegunjini le-pituitary, ikakhulukazi kwi-pituitary gland eholela ekukhiqizeni okwandayo kwe-prolactin, eyi-hormone ebhekele ukukhuthaza izindlala ezincelisayo ukukhiqiza ubisi ngesikhathi sokukhulelwa nangesikhathi sokuncelisa. Ukwanda kwenani leprolactin kuveza i-hyperprolactinemia, engaholela ekubonakaleni kwezimpawu ezithile njengokuya esikhathini okungajwayelekile, ukungabikho esikhathini, ukungabi nenzalo nokungabi namandla, endabeni yamadoda.

I-Prolactinoma ingahlukaniswa ngezinhlobo ezimbili ngosayizi wayo:

• I-Microprolactinoma, enobubanzi obungaphansi kuka-10 mm;
• I-Macroprolactinoma, enobubanzi obulingana noma obukhulu kune-10 mm.

Ukuxilongwa kwe-prolactinoma kwenziwa ngokulinganisa kwe-prolactin egazini kanye nomphumela wokuhlolwa kwe-imaging njenge-magnetic resonance kanye ne-computed tomography. Ukwelashwa kufanele kunconywe ngudokotela we-endocrinologist noma we-neurologist ngokusho kwezimpawu zesimila, futhi ukusetshenziswa kwezidakamizwa ukulawula amazinga e-prolactin nokuqeda izimpawu kuyakhonjiswa.

Izimpawu ze-Prolactinoma

Izimpawu ze-prolactinoma zihlobene nokwanda kwenani le-prolactin ejikelezayo, futhi kungahle kube khona:

• Ukukhiqizwa kobisi lwebele ngisho ngaphandle kokukhulelwa noma usanda kubeletha ingane;
• Ukuya esikhathini okungajwayelekile noma ukungayi esikhathini,
• Ukungabi nenzalo;
• Ukungabi namandla, esimweni samadoda;
• Ukwehla kwesifiso sobulili;
• Ukwanda kwamabele emadodeni.

Yize ukwanda kwenani leprolactin kuhlobene neprolactinoma, kungenzeka futhi ngenxa yezinye izimo ezinjenge-polycystic ovary syndrome, i-hypothyroidism, ingcindezi, ngesikhathi sokukhulelwa nokuncelisa, ukwehluleka kwezinso, ukwehluleka kwesibindi noma ngenxa yemithi ethile. Funda kabanzi ngezimbangela ze-hyperprolactinemia.

Ukuxilongwa kwenziwa kanjani

Ukuxilongwa kwe-prolactinoma kwenziwa ekuqaleni ngokubheka inani le-prolactin ejikelezayo futhi amanani angahluka ngokuya ngohlobo lwe-prolactinoma:

• Endabeni ye-microprolactinoma, amanani we-prolactin aphakathi kuka-50 no-300 ng / dL;
• Endabeni ye-macroprolactinoma, amanani we-prolactin aphakathi kuka-200 no-5000 ng / dL.

Ngaphezu kwesilinganiso sokujikeleza kwe-prolactin, udokotela uvame ukukhombisa ukusebenza kwe-computed tomography kanye ne-magnetic resonance imaging ukuze aqinisekise izici zalesi sifo. I-densitometry ye-Bone ne-echocardiogram nayo ingacelwa ukuze kubonakale uma kukhona umonakalo ohlobene nokwanda kwenani le-prolactin ejikelezayo.

Bona ukuthi kwenziwa kanjani ukuhlolwa kwe-prolactin nokuthi ungawuqonda kanjani umphumela.

Ukwelashwa kwe-prolactinoma

Ukwelashwa kwe-prolactinoma kuhlose ukunciphisa izimpawu nokubuyisa ukuzala, ngaphezu kokulawula ukujikeleza kwamazinga e-prolactin nokulawula ukukhula nokukhula kwesimila. Ulayini wokuqala wokwelashwa okhonjiswe yi-endocrinologist unezidakamizwa ezifana neBromocriptine neCabergoline.

Lapho amazinga e-prolactin engalawulwa, udokotela angancoma ukuhlinzwa ukuze kususwe isimila. Ngaphezu kwalokho, uma umuntu engaphenduli ekwelashweni ngemithi, i-radiotherapy inganconywa ukuze kulawulwe ubukhulu besimila futhi kuvimbele ukuqhubeka kwesifo.