I-Quinine: iyini, yenzelwa ini nemiphumela engemihle

-Delile

• Isetshenziswa kanjani
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

I-Quinine kwakuyisidakamizwa sokuqala ukusetshenziselwa ukwelapha umalaleveva, ngemuva kwesikhathi kwafakwa i-chloroquine, ngenxa yemiphumela yayo enobuthi nokusebenza kahle okuncane. Kodwa-ke, ngokuhamba kwesikhathi, ngokumelana ne- P. falciparum ku-chloroquine, i-quinine yasetshenziswa futhi, iyodwa noma ihlanganiswe nezinye izidakamizwa.

Yize le nto okwamanje ingathengiswa eBrazil, isasetshenziswa kwamanye amazwe ekwelapheni umalaleveva obangelwa amagciwane ePlasmodium amelana ne-chloroquine ne-Babesiosis, isifo esibangelwa amagciwane Babesia microti.

Isetshenziswa kanjani

Ekwelapheni kwabantu abadala umalaleveva, isilinganiso esinconywayo singama-600 mg (amaphilisi ama-2) njalo emahoreni ayi-8 izinsuku ezi-3 kuye kwezi-7. Ezinganeni, umthamo onconyiwe ngu-10 mg / kg njalo emahoreni ayi-8 izinsuku ezi-3 kuye kwezi-7.

Ekwelapheni i-Babesiosis, kujwayelekile ukuhlanganisa eminye imithi, njenge-clindamycin. Imithamo enconyiwe ingu-600 mg we-quinine, kathathu ngosuku, izinsuku eziyi-7. Ezinganeni, ukuphathwa kwansuku zonke kwe-10 mg / kg ye-quinine ehlotshaniswa ne-clindamycin kunconywa njalo emahoreni ayisishiyagalombili.

Ngubani ongafanele asebenzise

I-quinine iyaphikiswa kubantu abanezinto ezingezwani nokwelashwa kwale nto noma kunoma yiziphi izinto ezikhona kwifomula futhi akufanele isetshenziswe ngabesifazane abakhulelwe noma abancelisayo ngaphandle kokuyalelwa ngudokotela.

Ngaphezu kwalokho, akufanele futhi isetshenziswe ngabantu abane-glucose -6-phosphate dehydrogenase entula, abane-optic neuritis noma umlando we-swamp fever.

Imiphumela emibi engaba khona

Eminye yemiphumela emibi kakhulu engabangelwa yi-quinine ukubuyela emuva ekulahlekelweni kokuzwa, isicanucanu nokuhlanza.

Uma kwenzeka ukuphazamiseka okubonakalayo, ukuqubuka kwesikhumba, ukulahlekelwa ukuzwa noma i-tinnitus, umuntu kufanele ayeke ukuthatha umuthi ngokushesha.