Ingabe Ubuso Bakho Buba Bomvu Lapho Uphuza? Nakhu Kungani

-Delile

• Ngubani othinteka kalula?
• Kwenzakalani?
• Ingabe kuyingozi?
• Ukwelashwa
• Ngingakuvimbela?
• Izexwayiso
• Okubalulekile

Utshwala nokuhlanza ebusweni

Uma ubuso bakho buba bomvu ngemuva kwezingilazi ezimbalwa zewayini, awuwedwa. Abantu abaningi bahlangabezana nokushaywa ebusweni lapho bephuza utshwala. Igama lobuchwepheshe lalesi simo lithi "ukusabela okweqile kotshwala."

Isikhathi esiningi, ukuqhuma kwenzeka ngoba unenkinga yokugaya utshwala ngokuphelele.

Abantu abashayayo lapho bephuza bangaba nohlobo olungalungile lwe-aldehyde dehydrogenase 2 (ALDH2) gene. I-ALDH2 iyi-enzyme emzimbeni wakho esiza ukudiliza into yotshwala ebizwa nge-acetaldehyde.

I-acetaldehyde eningi kakhulu ingadala ubuso obomvu nezinye izimpawu.

Funda ukuze ufunde kabanzi mayelana nokuthi kungani ukuqhuma kwenzeka nokuthi yini ongayenza ngakho.

Ngubani othinteka kalula?

Ososayensi balinganisela ukuthi okungenani kunabantu emhlabeni wonke abanenkinga ye-ALDH2. Lokho kungamaphesenti ayisishiyagalombili wabantu.

Abantu bomdabu waseJapane, owamaShayina nowaseKorea banamathuba amaningi okuthi baphendule utshwala. Okungenani, futhi mhlawumbe kuze kufike kumaphesenti angama-70, abantu baseMpumalanga Asiya bahlangabezana nokushaywa ebusweni njengempendulo ekuphuzeni utshwala.

Eqinisweni, into ebomvu yobuso ibizwa ngokuthi "i-Asian flush" noma "ukukhanya kwe-Asia."

Olunye ucwaningo luye lwabonisa nokuthi abantu abanemvelaphi yamaJuda kungenzeka futhi ukuthi babe nethuba lokuguquka kwe-ALDH2.

Akwaziwa ukuthi kungani abantu abathile kungenzeka babe nalenkinga, kepha kuyizakhi zofuzo futhi kungadluliselwa ngumzali oyedwa noma bobabili.

Kwenzakalani?

I-ALDH2 imvamisa isebenza ukudiliza i-acetaldehyde. Lapho ushintsho lwezakhi zofuzo luthinta le enzyme, alwenzi umsebenzi walo.

Ukushoda kwe-ALDH2 kudala i-acetaldehyde eyengeziwe emzimbeni wakho. I-acetaldehyde eningi kakhulu ingakwenza ungabekezeleli utshwala.

Ukuhlanza uphawu olulodwa, kepha abantu abanalesi simo bangase babhekane nalokhu:

• ukushaya kwenhliziyo okusheshayo
• ikhanda
• isicanucanu
• ukuhlanza

Ingabe kuyingozi?

Yize ukuzikhukhumeza uqobo kungalimazi, kungaba uphawu oluxwayisayo ngezinye izingozi.

Ucwaningo olulodwa luka-2013 lukhombise ukuthi abantu abashaywa amanzi ngemuva kokuphuza bangaba namathuba aphezulu okuba nomfutho wegazi ophezulu.

Ososayensi babheka abesilisa baseKorea abayi-1,763 futhi bathola "ama-flusher" aphuza iziphuzo ezidakayo ezingaphezu kwezine ngesonto ayesengozini enkulu yokuba nomfutho wegazi ophezulu uma kuqhathaniswa nalabo ababengaphuzi nhlobo.

Kepha, "labo abangahambisi" babenamathuba amaningi okuba nomfutho wegazi ophakeme uma bephuza iziphuzo ezingaphezu kwesishiyagalombili ngesonto.

Ukuba nomfutho wegazi ophezulu kungakhuphula amathuba okuba nesifo senhliziyo nesifo sohlangothi.

Izifundo ezi-10 ezahlukahlukene zithole ukuthi ukuphendula ebusweni utshwala kuhlotshaniswa nengozi ephezulu yomdlavuza, ikakhulukazi umdlavuza wokuqina, emadodeni ase-East Asia. Kwakungahlotshaniswa nengozi yomdlavuza phakathi kwabesifazane.

Abanye odokotela bakholelwa ukuthi umphumela wokuhlanza ungasiza ekuboneni labo abasengozini yalezi zifo.

Ukwelashwa

Imithi ebizwa nge-histamine-2 (H2) blocker ingalawula ukuqhuma ebusweni. Le mithi isebenza ngokwehlisa ukwehla kotshwala ku-acetaldehyde egazini lakho. Ama-block block ajwayelekile we-H2 afaka:

• I-Pepcid
• Zantac
• I-Tagamet

I-Brimonidine kungenye indlela yokwelashwa okuthandwa kakhulu ukuqhuma ebusweni. Kuyinto yokwelapha ngezihloko okunciphisa ukubomvu kobuso okwesikhashana. Umuthi usebenza ngokunciphisa usayizi wemithambo yegazi emincane kakhulu.

Ukuphathwa Kwezokudla Nezidakamizwa e-U.S. I-FDA kuvume i-brimonidine ekwelapheni i-rosacea - isimo sesikhumba esidala ububomvu namaqhubu amancane ebusweni.

Olunye ukhilimu we-topical, i-oxymetazoline, wavunywa ngo-2017 ukwelapha i-rosacea. Kungasiza ukubomvu ebusweni ngokunciphisa imithwalo yegazi esikhunjeni.

Abanye abantu basebenzisa ama-lasers nezindlela zokwelapha ezenzelwe ukukhanya ukunciphisa ububomvu. Ukwelashwa kungasiza ekuthuthukiseni ukubukeka kwemithambo yegazi ebonakalayo.

Kubalulekile ukwazi ukuthi izindlela zokwelapha ezisiza ukugeleza azibhekane nokushoda kwe-ALDH2. Bangakwazi ukufihla izimpawu ezibalulekile ezingakhombisa inkinga.

Ngingakuvimbela?

Ukuphela kwendlela yokuvimbela ukuqhuma ebusweni ekuphuzeni ukugwema noma ukunciphisa ukusetshenziswa kwakho kotshwala. Lokhu kungaba umqondo omuhle, noma ngabe awunankinga ngokujika ubomvu.

Ngokwe-World Health Organisation (WHO), utshwala yibo obenza kube nokufa kwabantu abaningi emhlabeni.

I-WHO ithi utshwala "buyisici esiyimbangela" kokungaphezulu nokulimala.

Ukuphuza ngokweqile kungandisa ingozi yakho yokuthuthukisa izinkinga eziningi zezokwelapha, kufaka phakathi:

• isifo sesibindi
• ezinye izinhlobo zomdlavuza
• umfutho wegazi ophakeme
• isifo senhliziyo noma isifo sohlangothi
• izinkinga zememori
• izingqinamba zokugaya ukudla
• ukuthembela otshwaleni

Uma uphuza, zama ukuphuza ngokulinganisela. Lokhu kuchaza ukuphuza okulinganiselwe njengesiphuzo esisodwa ngosuku kwabesifazane neziphuzo ezimbili ngosuku kubantu besilisa.

Izexwayiso

Imithi efihla izimpawu zokungabekezelelani kotshwala ingakwenza uzizwe sengathi ungaphuza ngaphezu kokufanele. Lokhu kungaba yingozi, ikakhulukazi uma unokushoda kwe-ALDH2.

Khumbula, ukufutha ebusweni kungaba wuphawu lokuthi kufanele uyeke ukuphuza.

Okubalulekile

Ukuhlanza ebusweni ngenkathi uphuza imvamisa kungenxa yokushoda kwe-ALDH2, okungenza ukuphuza utshwala kube yingozi empilweni yakho. Abantu bomdabu wase-Asia nowamaJuda maningi amathuba okuba nale nkinga.

Ngenkathi ukwelashwa kungabufihla ububomvu, kumboza kuphela izimpawu zakho. Uma uzwa ukushaywa ebusweni ngenkathi uphuza, kufanele uzame ukunciphisa noma ukugwema utshwala.

Khuluma nodokotela wakho uma ucabanga ukuthi ungaba nokushoda kwe-ALDH2. Ukuhlolwa kuyatholakala ukuqinisekisa ukuthi unesakhi sofuzo esishintshiwe.