ISerotonin Syndrome

-Delile

• Ziyini izimpawu ze-serotonin syndrome?
• Ziyini izimbangela zesifo se-serotonin?
• Izidambisi
• Imithi ye-Migraine (isigaba se-triptan)
• Izidakamizwa ezingekho emthethweni
• Izithako zemithi
• Imithi ebandayo neyokukhwehlela
• Ihlonza kanjani i-serotonin syndrome?
• Yiziphi izindlela zokwelapha i-serotonin syndrome?
• Yiziphi izinkinga ezihambisana ne-serotonin syndrome?
• Uyini umbono wesikhathi eside?
• Ngingayivimbela kanjani i-serotonin syndrome?

Yini i-serotonin syndrome?

I-Serotonin syndrome iyindlela engaba yimbi kakhulu yokusabela kwezidakamizwa. Kukholakala ukuthi kwenzeka lapho i-serotonin eningi yakha emzimbeni wakho. Amaseli emizwa ngokuvamile akhiqiza i-serotonin. ISerotonin iyi-neurotransmitter, eyikhemikhali. Kuyasiza ukulawula:

• ukugaya
• ukugeleza kwegazi
• izinga lokushisa komzimba
• ukuphefumula

Iphinde ibambe iqhaza elibalulekile ekusebenzeni kahle kwamangqamuzana ezinzwa nobuchopho futhi kukholakala ukuthi inomthelela kumzwelo.

Uma uthatha imithi ehlukene ebekiwe ndawonye, ​​ungagcina une-serotonin eningi kakhulu emzimbeni wakho. Izinhlobo zemithi engaholela ku-serotonin syndrome ifaka phakathi leyo esetshenziselwa ukwelapha ukudangala kanye nekhanda le-migraine, nokuphatha ubuhlungu. I-serotonin eningi kakhulu ingadala izimpawu ezahlukahlukene ezimnene nezimbi. Lezi zimpawu zingathinta ubuchopho, imisipha, nezinye izingxenye zomzimba.

I-Serotonin syndrome ingenzeka uma uqala umuthi omusha ophazamisa i-serotonin. Kungenzeka futhi uma ukwandisa umthamo womuthi osuvele uwuthatha. Isimo kungenzeka ukuthi senzeke lapho kuthathwa izidakamizwa ezimbili noma ngaphezulu. I-Serotonin syndrome ingaba yingozi uma ungatholi ukwelashwa ngokushesha.

Ziyini izimpawu ze-serotonin syndrome?

Ungaba nezimpawu kungakapheli imizuzu noma amahora wokuthatha umuthi omusha noma ukwandisa umthamo womuthi okhona. Izimpawu zingafaka:

• ukudideka
• ukudideka
• ukucasuka
• ukukhathazeka
• ukuphazamiseka kwemisipha
• ukuqina kwemisipha
• ukuthuthumela
• ngiqhaqhazela
• isifo sohudo
• ukushaya kwenhliziyo okusheshayo, noma i-tachycardia
• umfutho wegazi ophakeme
• isicanucanu
• ukusangana
• ukucabanga ngokweqile, noma i-hyperreflexia
• abafundi abahlanzekile

Ezimweni ezimbi kakhulu, izimpawu zingafaka:

• ukungaphenduli
• ikhoma
• isithuthwane
• ukushaya kwenhliziyo okungajwayelekile

Ziyini izimbangela zesifo se-serotonin?

Imvamisa, lesi simo senzeka uma uhlanganisa imishanguzo emibili noma ngaphezulu, izidakamizwa ezingekho emthethweni, noma izithasiselo zokudla okunomsoco okwandisa amazinga e-serotonin. Isibonelo, ungathatha umuthi ukusiza nge-migraine ngemuva kokuthatha i-antidepressant. Izinhlobo ezithile zemithi kadokotela, njengama-antibiotic, ama-antivirals asetshenziselwa ukwelapha i-HIV ne-AIDS, kanye neminye imishanguzo kadokotela yesicanucanu nobuhlungu nayo ingakhuphula amazinga e-serotonin.

Izibonelo zezidakamizwa nezithako ezihambisana ne-serotonin syndrome zifaka:

Izidambisi

Izidambisi ezihlobene ne-serotonin syndrome zifaka:

• i-serotonin reuptake inhibitors ekhethiwe (i-SSRIs), efana noCelexa noZoloft
• i-serotonin ne-norepinephrine reuptake inhibitors (SNRIs), njenge-Effexor
• ama-tricyclic antidepressants, njenge-nortriptyline ne-amitriptyline
• i-monoamine oxidase inhibitors (i-MAOIs), efana neNardil neMarplan
• amanye ama-anti-depressants

Imithi ye-Migraine (isigaba se-triptan)

Imithi ye-Migraine esigabeni semithi esibizwa nge- “triptans” nayo ihlotshaniswa ne-serotonin syndrome. Lokhu kufaka phakathi:

• i-almotriptan (Axert)
• i-naratriptan (Amerge)
• i-sumatriptan (Imitrex)

Izidakamizwa ezingekho emthethweni

Izidakamizwa ezithile ezingekho emthethweni zihlotshaniswa ne-serotonin syndrome. Lokhu kufaka phakathi:

• I-LSD
• i-ecstasy (MDMA)
• icocaine
• ama-amphetamines

Izithako zemithi

Izithako ezithile zamakhambi zihlotshaniswa ne-serotonin syndrome. Lokhu kufaka phakathi:

• Isibungu iSt
• ginseng

Imithi ebandayo neyokukhwehlela

Imithi ethile yokubanda nokukhwehlela yasesitolo equkethe i-dextromethorphan ihlotshaniswa ne-serotonin syndrome. Lokhu kufaka phakathi:

• I-Robitussin DM
• UDelsym

Ihlonza kanjani i-serotonin syndrome?

Akukho ukuhlolwa kwelabhorethri okuqondile kwe-serotonin syndrome. Udokotela wakho angaqala ngokubuyekeza umlando nezimpawu zakho zezokwelapha. Qiniseka ukuthi utshela udokotela wakho uma ngabe uthatha noma imuphi umuthi noma usebenzise izidakamizwa ezingekho emthethweni emasontweni edlule. Lolu lwazi lungasiza udokotela wakho ukuthi enze ukuxilongwa okunembile.

Udokotela wakho uvame ukwenza ezinye izivivinyo eziningana. Lokhu kuzosiza udokotela wakho ukuthola ukuthi izitho ezithile noma ukusebenza komzimba kuthintekile yini. Bangasiza nodokotela wakho ukukhipha ezinye izimo.

Ezinye izimo zinezimpawu ezifanayo ne-serotonin syndrome. Lokhu kufaka phakathi ukutheleleka, ukweqisa izidakamizwa, nezinkinga zamahomoni. Isimo esaziwa njenge-neuroleptic malignant syndrome naso sinezimpawu ezifanayo. Ukusabela okungalungile emithini esetshenziselwa ukwelapha izifo zengqondo.

Ukuhlolwa udokotela wakho angaku-oda kufaka:

• ukubalwa kwegazi okuphelele (CBC)
• isiko legazi
• izivivinyo zomsebenzi wegilo
• izikrini zezidakamizwa
• ukuhlolwa kwezinso
• ukuhlolwa kwesibindi

Yiziphi izindlela zokwelapha i-serotonin syndrome?

Uma unesifo esincane kakhulu se-serotonin syndrome, udokotela wakho angakweluleka kuphela ukuthi uyeke ukuthatha imishanguzo edala inkinga ngokushesha.

Uma unezimpawu ezinzima, kuzodingeka uye esibhedlela. Esibhedlela, udokotela wakho uzosibhekisisa isimo sakho. Ungase futhi uthole ukwelashwa okulandelayo:

• ukuhoxiswa kwanoma imuphi umuthi obangele isimo
• uketshezi olufakwa emithanjeni lokwehlisa amanzi emzimbeni nomkhuhlane
• imithi esiza ukuqeda ukuqina kwemisipha noma ukuyaluza
• imithi evimba i-serotonin

Yiziphi izinkinga ezihambisana ne-serotonin syndrome?

Ukuqina kwemisipha kungaholela ekuwohlokeni kwezicubu zemisipha. Ukonakala kwalesi sicubu kungaholela ekulimaleni kanzima kwezinso. Kungadingeka isibhedlela sisebenzise imishanguzo ekhubaza imisipha yakho okwesikhashana ukuvimbela umonakalo ongaphezulu. Ishubhu lokuphefumula nokuphefumula kuzokusiza uphefumule.

Uyini umbono wesikhathi eside?

Umbono we-serotonin syndrome muhle kakhulu ngokwelashwa. Ngokuvamile azikho ezinye izinkinga lapho amazinga e-serotonin ebuyela kokujwayelekile. Kodwa-ke, i-serotonin syndrome ingaba yingozi uma ingalashwa.

Ngingayivimbela kanjani i-serotonin syndrome?

Awukwazi njalo ukuvimbela i-serotonin syndrome. Qiniseka ukuthi udokotela wakho uyazi ukuthi imiphi imithi oyisebenzisayo. Udokotela wakho kufanele akuqaphele eduze uma uthatha inhlanganisela yemithi eyaziwa ngokukhulisa amazinga e-serotonin. Lokhu kubaluleke kakhulu ngemuva nje kokuqala umuthi omusha noma ngemuva nje kokukhulisa isilinganiso sakho.

I-FDA idinga amalebula okuxwayisa emikhiqizweni ukuxwayisa iziguli ngobungozi be-serotonin syndrome.