Ukuhlolwa kwe-Estradiol

-Delile

• Kungani ngidinga ukuhlolwa kwe-estradiol?
• Yiziphi izingozi ezihambisana nokuhlolwa kwe-estradiol?
• Ngilungiselela kanjani ukuhlolwa kwe-estradiol?
• Kwenzekani ngesikhathi sokuhlolwa kwe-estradiol?
• Isho ukuthini imiphumela yokuhlolwa kwe-estradiol?

Kuyini ukuhlolwa kwe-estradiol?

Ukuhlolwa kwe-estradiol kukala inani le-hormone estradiol egazini lakho. Kubizwa nangokuthi ukuhlolwa kwe-E2.

I-Estradiol iyindlela ye-hormone estrogen. Ibizwa nangokuthi i-beta-estradiol eyi-17. Ama-ovari, amabele, nezindlala ze-adrenal zenza i-estradiol. Ngesikhathi sokukhulelwa, i-placenta nayo yenza i-estradiol.

I-Estradiol isiza ngokukhula nokuthuthuka kwezitho zobulili zabesifazane, kufaka phakathi:

• isibeletho
• amashubhu we-fallopian
• isitho sangasese sowesifazane
• amabele

I-Estradiol isiza ukulawula indlela amafutha asatshalaliswa ngayo emzimbeni wesifazane. Kubalulekile futhi emathanjeni nasempilweni ehlangene kwabesifazane.

Abesilisa nabo bane-estradiol emizimbeni yabo. Amaleveli abo e-estradiol aphansi kunamazinga abesifazane. Kwabesilisa, izindlala nama-testes adrenal enza i-estradiol. I-Estradiol ikhonjisiwe ku-vitro ukuvimbela ukubhujiswa kwamangqamuzana wesidoda, kepha ukubaluleka kwayo emtholampilo ekusebenzeni kocansi nasekuthuthukisweni kwamadoda kungenzeka kungabaluleki kangako kunabesifazane.

Kungani ngidinga ukuhlolwa kwe-estradiol?

Udokotela wakho anga-oda ukuhlolwa kwe-estradiol uma izici zobulili zowesifazane noma zesilisa zingakhuli ngezinga elijwayelekile. Izinga le-estradiol eliphakeme kunokujwayelekile likhombisa ukuthi ukuthomba kwenzeka ngaphambi kwesikhathi kunokujwayelekile. Lesi yisimo esaziwa ngokuthi ukuthomba ngaphambi kwesikhathi.

Amazinga aphansi e-estradiol angakhombisa ukuthomba sekwedlule isikhathi. Ukuhlolwa kungasiza udokotela wakho ukuthola ukuthi kunezinkinga yini ngezindlala zakho ze-adrenal. Kungasiza futhi ukunquma ukuthi ngabe ukwelashwa kwe-hypopituitarism, noma ukwehla komsebenzi we-pituitary gland, kuyasebenza.

Udokotela wakho angalawula ukuhlolwa kwe-estradiol ukuze afune izimbangela ze:

• izikhathi ezingavamile zokuya esikhathini
• ukopha okungavamile kwesitho sangasese sowesifazane
• ukungazali kwabesifazane

Udokotela wakho futhi angayalela ukuhlolwa kwe-estradiol uma umjikelezo wakho wokuya esikhathini umile futhi unezimpawu zokunqamuka kokuya esikhathini. Ngesikhathi nangemva kokuyeka ukuya esikhathini, umzimba wowesifazane uzokhiqiza kancane i-estrogen ne-estradiol, okufaka isandla kwizimpawu ezitholwa ngesikhathi sokunqamuka kokuya esikhathini. Ukuhlolwa kwezinga lakho le-estradiol kungasiza udokotela wakho ukuthi anqume ukuthi ulungiselela ukungena esikhathini noma ngabe usuvele udlula kunguquko.

Ukuhlolwa kwe-estradiol kungakhombisa nokuthi ama-ovari asebenza kahle kangakanani. Ngakho-ke, udokotela wakho angaphinde ahlele lokhu kuhlolwa uma unezimpawu zesimila se-ovarian. Izimpawu zifaka:

• ukuqumba noma ukuvuvukala esiswini sakho
• unenkinga yokudla ngenxa yokuzizwa usuthi ngemuva kokudla inani elincane lokudla
• ubuhlungu endaweni engezansi kwesisu nasesinqeni
• ukuncipha komzimba
• ukuchama kaningi

Uma ukhulelwe noma ukwelashwa kokuzala, udokotela wakho angayalela ukuhlolwa kwe-estradiol ukusiza ukugcina ithrekhi yenqubekela phambili yakho.

Ukuhlolwa kwe-estradiol ngokuvamile akusetshenziswanga wedwa ukwenza ukuxilongwa. Kodwa-ke, imiphumela yalolu vivinyo ingasiza udokotela wakho anqume ukuthi ngabe okunye ukuhlolwa kuyadingeka yini.

Abantu abelashwa i-transgender hormone therapy bangathola i-estradiol. Uma kunjalo, amazinga abo e-estradiol angahlolwa njalo futhi aqashwe odokotela babo.

Yiziphi izingozi ezihambisana nokuhlolwa kwe-estradiol?

Izingozi ezihambisana nokuhlolwa kwe-estradiol ziphansi. Kubandakanya:

• ama-punctures amaningi ngenxa yenkinga yokuthola umthambo
• ukopha ngokweqile
• ngizizwe nginekhanda elincane
• ukuquleka
• i-hematoma, okuwukuqoqwa kwegazi ngaphansi kwesikhumba sakho
• ukutheleleka endaweni yokubhoboza inaliti

Ngilungiselela kanjani ukuhlolwa kwe-estradiol?

Izici ezithile zingathinta amazinga e-estradiol. Kubalulekile ukuthi wena nodokotela wakho nixoxe ngalezi zinto. Bangakucela ukuthi uyeke ukuthatha umuthi othile noma ushintshe umthamo ngaphambi kokuhlolwa kwakho.

Imithi engathinta amazinga akho e-estradiol afaka:

• amaphilisi okuvimbela inzalo
• Ukwelashwa kwe-estrogen
• ama-glucocorticoids
• ama-phenothiazines, asetshenziselwa ukwelapha i-schizophrenia nezinye izifo zengqondo
• ama-antibiotic tetracycline (Panmycin) kanye ne-ampicillin

Amazinga e-Estradiol nawo angahluka usuku lonke nangomjikelezo wokuya esikhathini kowesifazane. Ngenxa yalokho, udokotela wakho angakucela ukuthi uhlolwe igazi lakho ngesikhathi esithile sosuku noma ngesikhathi esithile emjikelezweni wakho. Izimo ezingathinta amazinga e-estradiol zifaka:

• i-anemia
• umfutho wegazi ophakeme
• isifo sezinso
• ukunciphisa ukusebenza kwesibindi

Kwenzekani ngesikhathi sokuhlolwa kwe-estradiol?

Ukuhlolwa kwe-estradiol ukuhlolwa kwegazi. Lokhu kungabizwa nangokuthi ukudonswa kwegazi noma i-venipuncture. Uchwepheshe obizwa nge-phlebotomist uzokwenza ukuhlolwa kwegazi.

Igazi livame ukukhishwa emthanjeni ongaphakathi kwendololwane yakho noma ngemuva kwesandla sakho. Ukuqala, uchwepheshe uzosebenzisa isinqandakuvunda ukuhlanza isikhumba. Lokhu kusiza ukuvikela ukutheleleka. Bazobe sebegoqa i-tourniquet engalweni yakho engenhla. Lokhu kwenza umthambo uvuvukele igazi. Uchwepheshe uzobe esefaka inaliti emthanjeni wakho bese edonsela igazi kushubhu.

Uchwepheshe uzodonsa igazi elanele inani lezivivinyo ezi-odolwe ngudokotela wakho. Ukudonsa igazi kuzothatha kuphela imizuzu embalwa. Inqubo ingaba buhlungu kancane. Iningi labantu libika ukuzwa okuhlabayo noma okushisayo.

Ngemuva kokudonsa igazi, uchwepheshe uzofaka ingcindezi yokumisa ukopha. Bazofaka ibhandishi endaweni yokubhoboza bese bethumela isampula segazi lakho elabhorethri ukuze lihlolwe. Ukwehlisa ukulimaza, uchwepheshe angaqhubeka nokufaka ingcindezi esizeni imizuzu embalwa.

Isho ukuthini imiphumela yokuhlolwa kwe-estradiol?

Ngokusho kwe-Mayo Medical Laboratories, amazinga ajwayelekile e-estradiol (E2) abesifazane abasesikhathini asukela kuma-picograms ayi-15 kuye kwangama-350 ngemililitha (pg / mL). Kwabesifazane be-postmenopausal, amazinga ajwayelekile kufanele abe ngaphansi kuka-10 pg / mL.

Amazinga e-Estradiol aphezulu kunokujwayelekile angaphakamisa:

• ukuthomba kusencane
• izimila kuma-ovari noma kumasende
• gynecomastia, okuwukukhula kwamabele emadodeni
• hyperthyroidism, edalwa yindlala yegilo engasasebenzi ngokweqile
• i-cirrhosis, okuyisibazi sesibindi

Okuphansi kunamazinga ajwayelekile we-estradiol kungaphakamisa:

• ukunqamuka kokuya esikhathini
• I-Turner syndrome, okuyisifo sofuzo lapho owesifazane ene-X chromosome eyodwa esikhundleni sezimbili
• ukwehluleka kwe-ovari, noma ukuya esikhathini ngaphambi kwesikhathi, okwenzeka lapho ama-ovari eyeka ukusebenza ngaphambi kweminyaka yobudala engama-40
• i-polycystic ovarian syndrome (i-PCOS), isifo sehomoni esinezimpawu ezahlukahlukene okukholakala ukuthi siyimbangela ehamba phambili yokungabi nenzalo kwabesifazane
• ukukhiqizwa kwe-estrogen okuphelile, okungabangelwa amafutha omzimba aphansi
• hypopituitarism
• i-hypogonadism, eyenzeka lapho ama-ovari noma ama-testes engakhiqizi i-hormone eyanele

Lapho nje imiphumela yokuhlolwa kwakho kwezinga le-estradiol itholakala, udokotela wakho uzoxoxa ngemiphumela ngokuningiliziwe bese ekunika izinketho zokwelashwa.