Yini i-Lynch syndrome, izimbangela nokuthi ungayibona kanjani

-Delile

• Ungayibona kanjani i-Lynch syndrome
• Yini ebangela lesi sifo
• Ziyini izingozi zokuba ne-syndrome
• Yelashwa kanjani

I-Lynch syndrome yisimo esingavamile sezakhi zofuzo esandisa ingozi yomuntu yokuba nomdlavuza wamathumbu ngaphambi kweminyaka engama-50. Ngokuvamile imindeni ene-Lynch syndrome inenani eliphakeme ngokungajwayelekile lamacala omdlavuza wamathumbu, angasiza udokotela ukuthi axilonge.

Yize ingekho indlela elula yokwehlisa ubungozi bomdlavuza, ukuba nempilo enempilo nokugcina ama-aphoyintimenti ejwayelekile ne-gastroenterologist kunganciphisa amathuba okuba nezinkinga, noma ngabe kuvela umdlavuza, njengoba ukwelashwa kungaqalwa ngokushesha.

Ungayibona kanjani i-Lynch syndrome

I-Lynch syndrome yisimo sezakhi zofuzo, esingaholeli ekubonakaleni kwezimpawu noma izimpawu, ngakho-ke, ukuhlonza lolu shintsho kwenziwa ngokuhlolwa ngudokotela kweminye imibandela, efana nale:

• Ukuba nomdlavuza wamathumbu ngaphambi kweminyaka yobudala engama-50;
• Umlando womndeni womdlavuza wamathumbu kubantu abasha;
• Umlando womndeni wamacala amaningana womdlavuza wesibeletho;

Ngaphezu kwalokho, imindeni enezimo eziningi zomunye umdlavuza ohlobene, njenge-ovarian, isinye, noma umdlavuza wamasende, nayo ingaba ne-Lynch syndrome. Ngaphezu kokuhlonza ukuthi kwenziwa ngokuhlolwa kwezinqubo, isiqinisekiso singenziwa ngokuhlolwa kwezakhi zofuzo okuhlose ukukhomba ukuguquka kwezakhi zofuzo ezihlobene nalesi sifo.

Yini ebangela lesi sifo

I-Lynch syndrome yenzeka lapho kuvela ukungalungi kolunye zofuzo olubhekele ukuqeda izinguquko ku-DNA, kuvimbele ukubonakala komdlavuza. Lezi zofuzo zingabandakanya i-MLH1, i-MSH2, i-MSH6, i-PMS2 ne-EPCAM futhi, ngakho-ke, ukuhlolwa kwegazi laselebhu kwenziwa kaningi ukuqinisekisa lezi zinguquko.

Kodwa-ke, kukhona nezimo zemindeni ezethula lesi sifo ngaphandle koshintsho kulezi zinhlayiya ezi-5.

Ziyini izingozi zokuba ne-syndrome

Ngaphezu kwengozi eyengeziwe yokuthola umdlavuza wamathumbu ngaphambi kweminyaka yobudala engama-50, i-Lynch syndrome nayo ingathanda ukuthuthukiswa kwezinye izinhlobo zomdlavuza, njenge:

• Umdlavuza wesisu;
• Umdlavuza wesibindi noma wamapayipi enyongo;
• Umdlavuza womgudu womchamo;
• Umdlavuza wezinso;
• Umdlavuza wesikhumba;
• Umdlavuza wesibeletho noma amaqanda, esimweni sabesifazane;
• Isigaxa sobuchopho.

Ngenxa yengozi eyandayo yezinhlobo ezahlukahlukene zomdlavuza, kuyalulekwa ukuthi kuxoxiswane njalo ezindaweni ezikhethekile zezokwelapha ukuze kwenziwe izivivinyo futhi kukhonjwe noma yiziphi izinguquko kusenesikhathi. Ukuhlolwa okuvame ukwenziwa kulezi zimo ukwelulekwa ngezakhi zofuzo, lapho kuqinisekiswa khona ingozi yokuba nomdlavuza kanye nethuba lokudlulisela ufuzo ezinganeni. Qonda ukuthi kuyini ukwelulekwa ngezakhi zofuzo nokuthi kwenziwa kanjani.

Yelashwa kanjani

Akukho ukwelashwa okuqondile kwe-Lynch syndrome, kepha-ke, ezinye izindlela zokuqapha zingasiza ekunciphiseni ubungozi bomdlavuza njengokuthi ube nokudla okunempilo futhi okunempilo, ukuzijwayeza ukuzivocavoca umzimba njalo nokugwema ukubhema nokuphuza, ngoba lezi zinto zingavumela ukuthuthukiswa ezinye izinhlobo zomdlavuza.

Ngaphezu kwalokho, ukwandisa ukusetshenziswa kokudla okunothile kuma-antioxidants nakho kungasiza ekwehliseni ubungozi bomdlavuza. Bona iresiphi yamajusi amane alula asiza ukuvikela umdlavuza.