Izifo zikaWhipple

-Delile

• Izimpawu Ezihambisana Nezifo ZikaWhiphu
• Izimbangela Zezifo zikaWhipple
• Ukuhlonza Izifo Zemvubu
• I-Endoscopy
• Isidumbu
• Ukusabela Kwe-Polymerase Chain
• Ukuhlolwa Kwegazi
• Ukwelashwa Kwezifo zikaWhipple
• Umbono Wesikhathi Eside

Siyini Isifo SikaWhipple?

Amagciwane abiziwe I-Tropheryma whipplei kubangela isifo sikaWhipple. La mabhaktheriya athinta uhlelo lokugaya ukudla futhi angadlulela ku:

• inhliziyo
• amaphaphu
• ubuchopho
• amalunga
• isikhumba
• amehlo

Yisifo esingajwayelekile, kodwa singasongela impilo.

Kukholakala kabanzi ukuthi kukhona ukuthambekela kofuzo ekuthuthukiseni ukugula. Amadoda amhlophe aphakathi kuka-40 no-60 maningi amathuba okuthi asithole lesi simo kunanoma yiliphi elinye iqembu. Izinga lesifo sikaWhipple nalo livame ukuba phezulu ezindaweni ezingenawo amanzi angenasawoti kanye nokukhucululwa kwendle okufanele. Njengamanje, ayikho indlela eyaziwayo yokuvimbela isifo sikaWhipple.

Izimpawu Ezihambisana Nezifo ZikaWhiphu

Isifo sikaWhipple sivimbela umzimba wakho ekutholeni izakhamzimba ngendlela efanele. Ngenxa yalokhu, kuthinta izingxenye eziningi zomzimba futhi kuhlotshaniswa nezimpawu ezahlukahlukene. Ezigabeni ezithuthukile zesifo, ukutheleleka kungasakazeka kusuka emathunjini kuye kwezinye izitho ezinjenge:

• inhliziyo
• amaphaphu
• ubuchopho
• amalunga
• amehlo

Izimpawu nezimpawu ezivame kakhulu zesifo sikaWhipple zihlanganisa:

• ubuhlungu obungapheli obuhlangene
• isifo sohudo esingapheli esingaba negazi
• ukuncipha okukhulu kwesisindo
• ubuhlungu besisu nokuqunjelwa
• ukuncipha kokubona nobuhlungu bamehlo
• imfiva
• ukukhathala
• i-anemia, noma ukubalwa kwamangqamuzana egazi abomvu aphansi

Lezi zimpawu nezimpawu ezilandelayo azenzeki kaningi kepha zingakhombisa ukuthi isimo siya ngokuya siba sibi:

• ukuguqulwa kwesikhumba
• i-lymph node ezivuthayo
• ukukhwehlela okungapheli
• ubuhlungu esifubeni
• i-pericarditis, noma ukuvuvukala kwesaka elizungeze inhliziyo
• ukuhluleka kwenhliziyo
• inhliziyo ibubula
• ukungaboni kahle
• ukuwohloka komqondo
• ukuba ndikindiki
• ukuqwasha
• ubuthakathaka bemisipha
• ama-tics
• ukuhamba kanzima
• inkumbulo embi

Izimbangela Zezifo zikaWhipple

Ukutheleleka nge- T. whipplei amabhaktheriya yisona sizathu esisodwa esaziwayo se-Whipple's. Amagciwane azoholela ekwakhiweni kwezilonda zangaphakathi futhi abangele nezicubu zomzimba ukuqina.

Ama-villi yizicubu ezinjengomunwe ezimunca izakhi emathunjini amancane. Lapho i-villi iqala ukuqina, ukuma kwayo kwemvelo kuqala ukushintsha. Lokhu kulimaza i-villi futhi kuyivimbe ukuthi ingamunci ngempumelelo izakhamzimba. Lokhu kuholela ezinkingeni eziningi zesifo sikaWhipple.

Ukuhlonza Izifo Zemvubu

Ukuxilongwa kwesifo sikaWhipple kuyinkimbinkimbi, ikakhulukazi ngoba izimpawu ziyefana nezinye izimo ezivamile ezivela ebangeni lesifo se-celiac kuye ezinkingeni zezinzwa. Udokotela wakho uzozama ukukhipha lezi ezinye izimo ngaphambi kokukuxilonga ngesifo sika-Whipple.

I-Endoscopy

Uphawu lokuqala udokotela wakho azolubheka ukuthola ukuthi unaso yini isifo sikaWhipple yizilonda. I-endoscopy ukufaka ishubhu elincane eliguquguqukayo phansi komphimbo wakho kuya emathunjini amancane. Ishubhu inekhamera encane enamathiselwe. Udokotela wakho uzobona isimo sezindonga zakho zamathumbu. Izindonga ezijiyile ezinamakhava aluhlaza okotshani, anamawashi angaba uphawu lweWhipple's.

Isidumbu

Ngesikhathi se-endoscopy, udokotela wakho angasusa izicubu ezindongeni zakho zamathumbu ukuze avivinye ubukhona be- T. whipplei amagciwane. Le nqubo ibizwa ngokuthi yi-biopsy futhi ingaqinisekisa ukutheleleka.

Ukusabela Kwe-Polymerase Chain

Ukusabela kwamaketanga e-Polymerase yisivivinyo esibucayi kakhulu esandisa i-DNA ye T. whipplei kusuka kumasampula wakho wezicubu. Uma amabhaktheriya abe sezicutshini zakho, kuzoba nobufakazi be-DNA yako. Lokhu kuhlolwa kungaqinisekisa ubukhona be- T. whipplei amagciwane ezicutshini zakho.

Ukuhlolwa Kwegazi

Udokotela wakho angalawula inani eliphelele legazi. Lokhu kuzosiza ekutholeni ukuthi unesibalo esiphansi samangqamuzana abomvu egazi namanani aphansi e-albumin, okuyizimpawu zombili zokushoda kwegazi. I-anemia iyinkomba yokuthi ungaba nesifo sikaWhipple.

Ukwelashwa Kwezifo zikaWhipple

Inkambo enolaka yama-antibiotic imvamisa iyisinyathelo sokuqala ekwelashweni, kufaka phakathi amasonto amabili ama-antibiotics nge-intravenous (IV). Ngaphezu kwalokho, cishe uzoba kuma-antibiotics nsuku zonke unyaka owodwa noma emibili.

Ezinye izinketho zokwelashwa zifaka:

• ukufaka amanani afanele oketshezi
• uthatha imithi elwa nomalaleveva izinyanga eziyi-12 kuya kweziyi-18
• usebenzisa izengezo zensimbi ukusiza nge-anemia
• ukuthatha i-vitamin D, i-vitamin K, i-calcium, ne-magnesium supplements
• ukugcina ukudla okunekhalori eliphezulu ukusiza ngokumunca izakhi zomzimba
• ukuthatha i-corticosteroids ukusiza ukunciphisa ukuvuvukala
• ukuthatha imishanguzo yezinhlungu ezingezona eze-steroidal, njenge-ibuprofen

Isifo sikaWhipple yisifo segciwane esingaholela ekufeni uma singelashwa kahle.

Umbono Wesikhathi Eside

Ngemuva kokuqala ukwelashwa, izimpawu eziningi zizophela kungakapheli inyanga. Into engcono kakhulu ongayenza ukuqhubeka nokuphuza ama-antibiotic akho. Ukubuyela emuva kuvamile. Lapho zenzeka, izimpawu ezingeziwe, njengezinkinga zemizwa, zingabonakala nazo.