I-hepatitis ezenzakalelayo

I-autoimmune hepatitis ukuvuvukala kwesibindi. Kwenzeka lapho amangqamuzana omzimba enza iphutha emangqamuzaneni ejwayelekile esibindi sabahlaseli abayingozi futhi awahlasela.

Leli fomu le-hepatitis liyisifo esizimele. Amasosha omzimba awakwazi ukwehlukanisa phakathi kwezicubu zomzimba ezinempilo nezinto eziyingozi, zangaphandle.Umphumela uba ukuphendula komzimba okucekela phansi izicubu zomzimba ezijwayelekile.

Ukuvuvukala kwesibindi, noma i-hepatitis, kungenzeka kanye nezinye izifo ezizimele. Lokhu kufaka phakathi:

• Isifo samathuna
• Isifo samathumbu esivuthayo
• Isifo samathambo
• I-Scleroderma
• Isifo seSjögren
• Uhlelo lupus erythematosus
• Indlala yegilo
• Thayipha isifo sikashukela sokuqala
• I-ulcerative colitis

I-autoimmune hepatitis ingenzeka emalungwini omndeni wabantu abanezifo ezizimele. Kungaba khona imbangela yofuzo.

Lesi sifo sitholakala kakhulu emantombazaneni nakwabesifazane abancane.

Izimpawu zingafaka:

• Ukukhathala
• Ukungakhululeki okuvamile, ukungakhululeki, noma ukugula (malaise)
• Ukulunywa
• Ukuphelelwa isifiso sokudla
• Isicanucanu noma ukuhlanza
• Ubuhlungu obuhlangene
• Izitulo ezinombala ophuzi noma ezinobumba
• Umchamo omnyama
• Ukuhlukaniswa kwesisu

Ukungabikho esikhathini (amenorrhea) nakho kungaba uphawu.

Ukuhlolwa kwe-hepatitis ezenzakalelayo kufaka phakathi ukuhlolwa kwegazi okulandelayo:

• Ukuhlolwa kokusebenza kwesibindi
• I-anti-liver kidney microsome type 1 antibody (anti LKM-1)
• I-anti-nuclear antibody (ANA)
• I-anti-smooth muscle antibody (i-SMA)
• I-Serum IgG
• I-biopsy yesibindi ukubheka i-hepatitis yesikhathi eside

Ungadinga i-prednisone noma eminye imithi ye-corticosteroid ukusiza ukunciphisa ukuvuvukala. I-Azathioprine ne-6-mercaptopurine yizidakamizwa ezisetshenziselwa ukwelapha ezinye izifo ezizimele. Bakhonjisiwe ukuthi basiza abantu abane-autoimmune hepatitis, futhi.

Abanye abantu bangadinga ukufakelwa kwesibindi.

Umphumela uyehluka. Imithi ye-Corticosteroid inganciphisa ukuqhubeka kwesifo. Kodwa-ke, i-hepatitis ezenzakalelayo ingaqhubekela phambili ibe yi-cirrhosis. Lokhu kuzodinga ukufakelwa kwesibindi.

Izinkinga zingafaka:

• Isifo sokuqina kwesibindi
• Imiphumela emibi evela kuma-steroids kanye neminye imithi
• I-hepatocellular carcinoma
• Ukuhluleka kwesibindi

Shayela umhlinzeki wakho wezokunakekelwa kwempilo uma ubona izimpawu ze-hepatitis ezenzakalelayo.

I-hepatitis ezenzakalelayo ayikwazi ukuvinjelwa ezimweni eziningi. Ukwazi izinto ezinobungozi kungakusiza ukuthi usithole futhi uselaphe lesi sifo ngaphambi kwesikhathi.

Lupoid hepatitis

• Uhlelo lokugaya ukudla
• Izitho zohlelo lokugaya ukudla

Czaja AJ. I-hepatitis ezenzakalelayo. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 90.

UPawlotsky JM. I-hepatitis engapheli yegciwane kanye ne-autoimmune. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 149.