I-goiter nodular enobuthi

I-goiter nodular enobuthi ifaka indlala yegilo eyandisiwe. Indlala iqukethe izindawo ezikhule ngosayizi futhi zakha amaqhuqhuva. Eyodwa noma amaningi ala maqhubu akhiqiza i-hormone yegilo eningi kakhulu.

I-goiter nodular enobuthi iqala kusuka ku-goiter elula ekhona. Kwenzeka kaningi kubantu abadala asebekhulile. Izinto ezinobungozi zifaka ukuba ngowesifazane nangaphezulu kweminyaka engama-55 ubudala. Lesi sifo asivamile ezinganeni. Abantu abaningi abayisungulayo banesifo sokuvuvukala esinamaqhuqhuva iminyaka eminingi. Kwesinye isikhathi indlala yegilo ikhuliswa kancane, kanti i-goiter ibingakatholakali.

Kwesinye isikhathi, abantu abane-goiter enama-multinodular enobuthi bazokhula amazinga aphezulu e-thyroid okokuqala ngqa. Lokhu kwenzeka kakhulu ngemuva kokuba bethathe inani elikhulu le-iodine ngomthambo (ngemithambo) noma ngomlomo. Iodine ingasetshenziswa njengehlukile kwe-CT scan noma i-catheterization yenhliziyo. Ukuthatha imithi equkethe iodine, efana ne-amiodarone, nakho kungaholela ekuphazamisekeni. Ukusuka ezweni elinenkinga ye-iodine uye ezweni elinama-iodine amaningi ekudleni nakho kungashintsha i-goiter elula ibe i-goiter enobuthi.

Izimpawu zingafaka noma yikuphi okulandelayo:

• Ukukhathala
• Ukuhamba kwamathumbu kaningi
• Ukungabekezelelani kokushisa
• Ukwanda kwesifiso
• Ukujuluka okwengeziwe
• Isikhathi esingajwayelekile sokuya esikhathini (kwabesifazane)
• Amajaqamba emisipha
• Ukwesaba
• Ukungahlaliseki
• Ukwehla kwesisindo

Abantu abadala asebekhulile bangaba nezimpawu ezingacacisiwe. Lokhu kungafaka:

• Ubuthakathaka nokukhathala
• Ukushayana kobuhlungu nobuhlungu besifuba noma ingcindezi
• Izinguquko kwimemori kanye nemizwelo

I-goiter nodular enobuthi ayibangeli amehlo aqhamukayo angenzeka ngesifo se-Graves. Isifo se-Graves yisifo sokuzilimaza esiholela ekuguleni kwe-thyroid okungaphezu kwamandla (hyperthyroidism).

Ukuhlolwa komzimba kungakhombisa i-nodule eyodwa noma eziningi ku-thyroid. Indlala yegilo ivame ukukhuliswa. Kungaba nokushaya kwenhliziyo okusheshayo noma ukuthuthumela.

Olunye uvivinyo olungenziwa lubandakanya:

• Amazinga ama-hormone e-serum thyroid (T3, T4)
• I-Serum TSH (i-hormone evuselela i-thyroid)
• Ukuthathwa kwe-thyroid nokuskena noma ukutholwa kwe-iodine enemisebe
• I-ultrasound yegilo

Ama-beta blockers angalawula ezinye zezimpawu ze-hyperthyroidism kuze kube yilapho amazinga wehomoni yegilo emzimbeni elawulwa.

Imithi ethile ingavimba noma iguqule ukuthi indlala yegilo isebenzisa iodine kanjani. Lezi zingasetshenziselwa ukulawula indlala yegilo engasebenzi kunoma yiziphi izimo ezilandelayo:

• Ngaphambi kokuhlinzwa noma ukwelashwa kwe-radioiodine kwenzeka
• Njengokwelashwa kwesikhathi eside

Ukwelashwa kwe-Radioiodine kungasetshenziswa. Iodine enemisebe inikezwa ngomlomo. Bese igxila kwizicubu ze-thyroid ezedlulele futhi idale umonakalo. Ezimweni ezingavamile, ukushintshwa kwe-thyroid kuyadingeka kamuva.

Ukuhlinzwa ukususa i-thyroid kungenziwa lapho:

• I-goiter enkulu kakhulu noma i-goiter ibangela izimpawu ngokwenza kube nzima ukuphefumula noma ukugwinya
• Umdlavuza wegilo ukhona
• Ukwelashwa okusheshayo kuyadingeka

I-goiter nodular enobuthi ikakhulukazi isifo sabantu abadala asebekhulile. Ngakho-ke, ezinye izinkinga zempilo ezingamahlalakhona zingathinta imiphumela yalesi simo. Umuntu omdala osekhulile kungenzeka angakwazi ukubekezelela umphumela wesifo enhliziyweni. Kodwa-ke, lesi simo siyelapheka ngemithi.

Izinkinga zenhliziyo:

• Ukwehluleka kwenhliziyo
• Ukushaya kwenhliziyo okungajwayelekile (i-atrial fibrillation)
• Ukushaya kwenhliziyo okusheshayo

Ezinye izinkinga:

• Ukulahleka kwamathambo okuholela ekuthopheni kwamathambo

Inkinga ye-thyroid noma isiphepho ukuwohloka okukhulu kwezimpawu ze-hyperthyroidism. Kungenzeka nokutheleleka noma ukucindezeleka. Inkinga ye-thyroid ingabangela:

• Ubuhlungu besisu
• Ukwehla kokuqapha kwengqondo
• Imfiva

Abantu abanalesi simo badinga ukuya esibhedlela ngokushesha.

Izinkinga zokuba ne-goiter enkulu kakhulu zingafaka ukuphefumula kanzima noma ukugwinya. Lezi zinkinga zibangelwa ingcindezi ephaseji lendiza (i-trachea) noma i-esophagus, elilele ngemuva kwe-thyroid.

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma unezimpawu zalesi sifo esichazwe ngenhla. Landela imiyalo yomhlinzeki ngokuvakashelwa okulandelwayo.

Ukuvimbela i-goiter nodular enobuthi, phatha i-hyperthyroidism ne-goiter elula njengoba umhlinzeki wakho esikisela.

I-goiter multinodular enobuthi; Isifo seplummer; I-Thyrotoxicosis - i-nodular goiter; I-thyroid engasebenzi ngokweqile - i-goiter enobuthi enobuthi; I-Hyperthyroidism - i-goiter enobuthi enobuthi; I-goiter multinodular enobuthi; MNG

• Ukwandiswa kwe-thyroid - i-scintiscan
• Indlala yegilo

U-Hegedus L, uPaschke R, uKrohn K, uBonnema SJ. I-goiter yama-multinodular. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 90.

UJonklaas J, Cooper DS. Indlala yegilo. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 213.

UKopp P. Ukusebenza ngokuzimela kwamaqhuqhuva we-thyroid nezinye izimbangela ze-thyrotoxicosis. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 85.

Ritter JM, Imbali R, Henderson G, Loke YK, MacEwan D, Rang HP. Indlala yegilo. Ku: Ritter JM, Imbali R, Henderson G, Loke YK, MacEwan D, Rang HP, eds. URang noDale’s Pharmacology. Umhlaka 9. IPhiladelphia, PA: Elsevier; 2020: isahluko 35.

USmith PW, uHanks LR, uSalomone LJ, uHanks JB. Indlala yegilo. Ku: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. ISabiston Incwadi Yokuhlinzwa. Umhla ka-20. IPhiladelphia, PA: Elsevier; 2017: isahluko 36.