I-Pellagra

I-Pellagra yisifo esenzeka lapho umuntu engatholi i-niacin eyanele (enye yamavithamini ayinkimbinkimbi B) noma i-tryptophan (i-amino acid).

I-Pellagra ibangelwa ukuba ne-niacin encane noma i-tryptophan ekudleni. Kungenzeka futhi uma umzimba uhluleka ukumunca lezi zakhamzimba.

I-Pellagra nayo ingakhula ngenxa ye:

• Izifo zesisu
• Ukuhlinzwa kwesisindo (bariatric)
• I-Anorexia
• Ukuphuza ngokweqile
• I-Carcinoid syndrome (iqembu lezimpawu ezihambisana nezicubu zamathumbu amancane, ikholoni, isithasiselo kanye namashubhu e-bronchial emaphashini)
• Imithi ethile, efana ne-isoniazid, 5-fluorouracil, 6-mercaptopurine

Lesi sifo sivamile ezingxenyeni zomhlaba (ezingxenyeni ezithile ze-Afrika) lapho abantu benommbila omningi ongelashwa ekudleni kwabo. Ummbila ungumthombo ompofu we-tryptophan, kanti i-niacin emmbileni iboshelwe nakwezinye izingxenye zezinhlamvu. I-Niacin ikhishwa emmbileni uma icwiliswe emanzini amakhemikhali ubusuku bonke. Le ndlela isetshenziselwa ukupheka ama-tortilla eMelika Ephakathi lapho i-pellagra ingandile khona.

Izimpawu ze-pellagra zifaka:

• Ukudideka noma ukudideka kwengqondo
• Uhudo
• Ubuthakathaka
• Ukuphelelwa isifiso sokudla
• Ubuhlungu esiswini
• Ulwelwesi lwamafinyila oluvuvukile
• Izilonda zesikhumba ezinamaxolo, ikakhulukazi ezindaweni ezivezwa yilanga zesikhumba

Umhlinzeki wakho wokunakekelwa kwezempilo uzokwenza ukuhlolwa komzimba. Uzobuzwa ngokudla okudlayo.

Ukuhlolwa okungenziwa kufaka ukuhlolwa komchamo ukubheka ukuthi umzimba wakho une-niacin eyenele yini. Ukuhlolwa kwegazi nakho kungenziwa.

Umgomo wokwelashwa ukwandisa izinga le-niacin yomzimba wakho. Uzonikezwa izithako ze-niacin. Ungadinga futhi ukuthatha ezinye izithasiselo. Landela imiyalo yomhlinzeki wakho ngokuthe ngqo ngokuthi ungakanani futhi uzithathe kangaki izithasiselo.

Izimpawu ngenxa ye-pellagra, njengezilonda zesikhumba, zizokwelashwa.

Uma unezimo ezibanga i-pellagra, nazo zizolashwa.

Abantu bavame ukwenza kahle ngemuva kokuthatha i-niacin.

Uma ingalashwa, i-pellagra ingaholela ekulimaleni kwemizwa, ikakhulukazi ebuchosheni. Izilonda zesikhumba zingatheleleka.

Shayela umhlinzeki wakho uma unezimpawu ze-pellagra.

I-Pellagra ingavinjelwa ngokulandela ukudla okunomsoco.

Thola ukwelashwa ngezinkinga zempilo ezingadala i-pellagra.

Ukuntuleka kwe-Vitamin B3; Ukushoda - niacin; Ukushoda kweNicotinic acid

• Ukusilela kwe-Vitamin B3

U-Elia M, uLanham-New SA. Ukudla okunomsoco. Ku: Kumar P, Clark M, ama-eds. I-Kumar and Clarke's Clinical Medicine. Umhlaka 9. IPhiladelphia, PA: Elsevier; I-2017: isahluko 10.

UMeisenberg G, uSimmons WH. Izakhamzimba. Ku: Meisenberg G, Simmons WH, ama-eds. Izimiso ze-Medical Biochemistry. Umhla wesi-4. IPhiladelphia, PA: Elsevier; I-2017: isahluko 31.

Ngakho-ke i-YT. Ukuntuleka kwezifo zesimiso sezinzwa. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 85.