Ukushoda kwefolate

Ukushoda kwe-folate kusho ukuthi une-folic acid ephansi kunejwayelekile, uhlobo lukavithamini B, egazini lakho.

I-Folic acid (uvithamini B9) isebenza novithamini B12 novithamini C ukusiza umzimba wehle, usebenzise futhi wakhe amaprotheni amasha. Uvithamini usiza ukwakha amangqamuzana egazi abomvu namhlophe. Kuyasiza futhi ukukhiqiza i-DNA, isakhiwo sokwakha umzimba womuntu, esiphethe imininingwane yezofuzo.

I-Folic acid wuhlobo lwevithamini B. oncibilika emanzini. Lokhu kusho ukuthi ayigcinwa ezicutshini ezinonile zomzimba. Inani elisele levithamini lishiya umzimba ngomchamo.

Ngoba i-folate ayigcinwanga emzimbeni ngamanani amakhulu, amazinga egazi lakho azokwehla ngemuva kwamasonto ambalwa nje wokudla ukudla okune-folate. I-Folate itholakala ikakhulu ngemidumba, imifino enamaqabunga, amaqanda, ama-beet, ubhanana, izithelo ezisawolintshi nesibindi.

Abanikeli bokushoda kwamanga bafaka:

• Izifo lapho i-folic acid ingangeni kahle ohlelweni lokugaya ukudla (njengesifo seCeliac noma isifo seCrohn)
• Ukuphuza kakhulu utshwala
• Ukudla izithelo nemifino okuphekwe ngokweqile. I-Folate ingabhujiswa kalula ukushisa.
• I-hemolytic anemia
• Imithi ethile (efana ne-phenytoin, sulfasalazine, noma i-trimethoprim-sulfamethoxazole)
• Ukudla ukudla okungenampilo okungafaki izithelo nemifino eyanele
• I-dialysis yezinso

Ukushoda kwe-folic acid kungadala:

• Ukukhathala, ukucasuka, noma isifo sohudo
• Ukukhula okubi
• Ulimi olubushelelezi noluthambile

Ukushoda kwe-folate kungatholakala ngokuhlolwa kwegazi. Abesifazane abakhulelwe bavame ukuthola lokhu kuhlolwa kwegazi lapho behlolwa ngaphambi kokubeletha.

Izinkinga zifaka:

• I-anemia (inani eliphansi elibomvu lamaseli egazi)
• Amazinga aphansi amangqamuzana amhlophe egazi nama-platelets (ezimweni ezinzima)

Ekushodeni kwe-folate, amaseli abomvu egazi makhulu ngokungajwayelekile (megaloblastic).

Abesifazane abakhulelwe badinga ukuthola i-folic acid eyanele. Uvithamini ubalulekile ekukhuleni komgogodla nengqondo yomntwana. Ukushoda kwe-folic acid kungadala ukukhubazeka okukhulu kokuzalwa okwaziwa njengokukhubazeka kwe-neural tube. I-Recommended Dietary Allowance (RDA) ye-folate ngesikhathi sokukhulelwa ingama-micrograms ayi-600 (µg) / ngosuku.

Indlela engcono yokuthola amavithamini umzimba wakho udinga ukudla ukudla okunomsoco. Iningi labantu e-United States lidla i-folic acid eyanele ngoba liningi ekunikezelweni kokudla.

I-Folate ivela ngokwemvelo kulokhu kudla okulandelayo:

• Ubhontshisi nemidumba
• Izithelo nojusi
• Imifino eluhlaza njengama sipinashi, isilimo esinengono emnandi edliwayo, ne-broccoli
• Isibindi
• Amakhowe
• Izinkukhu, ingulube ne-shellfish
• Ukolweni bran kanye nokunye okusanhlamvu

I-Institute of Medicine Food and Nutrition Board incoma ukuthi abantu abadala bathole ama-µg angama-400 dailyg nsuku zonke. Abesifazane abangakhulelwa kufanele bathathe izithasiselo ze-folic acid ukuqinisekisa ukuthi bathola okwanele usuku ngalunye.

Izincomo ezithile zincike ebudaleni bomuntu, ubulili, nezinye izinto (njengokukhulelwa nokuncelisa).Ukudla okuningi, njengokudla okusanhlamvu kwasekuseni okuqinisiwe, manje kune-folic acid eyengeziwe engezwe ukusiza ukuvimbela ukukhubazeka kokuzalwa.

Ukushoda - i-folic acid; Ukushoda kwe-acid

• I-trimester yokuqala yokukhulelwa
• I-folic acid
• Amasonto okuqala okukhulelwa

U-Antony AC. Ama-anemias we-Megaloblastic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 39.

I-Koppel BS. Izinkinga ze-neurologic ezihlobene nokudla okunempilo kanye notshwala. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 388.

Izinkinga zikaSamuels P. Hematologic zokukhulelwa. Ku: Gabbe SG, Niebyl JR, Simpson JL, et al, eds. Ama-Obstetrics: Ukukhulelwa Okujwayelekile Nenkinga. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2017: isahluko 44.