I-Lupus nephritis

ILupus nephritis, okuyinkinga yezinso, iyinkinga ye-systemic lupus erythematosus.

Isystemic lupus erythematosus (SLE, noma lupus) isifo esizimele. Lokhu kusho ukuthi kunenkinga ngokuzivikela komzimba.

Imvamisa amasosha omzimba asiza ukuvikela umzimba ekuthelelekeni noma ezintweni eziyingozi. Kodwa kubantu abanesifo sokuzivikela komzimba, amasosha omzimba awakwazi ukwehlukanisa phakathi kwezinto eziyingozi neziphilile. Ngenxa yalokho, amasosha omzimba ahlasela amaseli nezinye izicubu ezinempilo.

I-SLE ingalimaza izingxenye ezehlukene zezinso. Lokhu kungaholela ezinkingeni ezinjengalezi:

• I-nephritis yangaphakathi
• I-Nephrotic syndrome
• I-glomerulonephritis ekhunjulwayo
• Ukuhluleka kwezinso

Izimpawu ze-lupus nephritis zifaka:

• Igazi emchameni
• Ukubukeka kwegwebu emchameni
• Ukuvuvukala (i-edema) kwanoma iyiphi indawo yomzimba
• Umfutho wegazi ophezulu

Umhlinzeki wezokunakekelwa kwempilo uzokwenza ukuhlolwa komzimba abuze ngezimpawu zakho. Imisindo engajwayelekile ingazwakala lapho umhlinzeki elalela inhliziyo yakho namaphaphu.

Ukuhlolwa okungenziwa kufaka phakathi:

• Isihloko se-ANA
• BUN futhi creatinine
• Qedela amazinga
• Ukuhlolwa komchamo
• Amaprotheni omchamo
• I-biopsy yezinso, ukuthola ukwelashwa okufanele

Inhloso yokwelashwa ukuthuthukisa ukusebenza kwezinso nokubambezela ukwehluleka kwezinso.

Imithi ingafaka izidakamizwa ezicindezela amasosha omzimba, njenge-corticosteroids, i-cyclophosphamide, i-mycophenolate mofetil, noma i-azathioprine.

Ungadinga i-dialysis ukulawula izimpawu zokuhluleka kwezinso, kwesinye isikhathi isikhashana kuphela. Ukufakelwa kwezinso kunganconywa. Abantu abane-lupus esebenzayo akufanele bafakelwe ngoba isimo singenzeka ezinso ezifakiwe.

Wenza kahle kangakanani, kuya ngohlobo oluthile lwe-lupus nephritis. Ungaba nama-flare-ups, bese kuba nezikhathi lapho ungenazo izimpawu.

Abanye abantu abanalesi simo baba nezinso zesikhathi eside (ezingalapheki).

Yize i-lupus nephritis ingabuya ezinso elitshalwe kabusha, kuyaqabukela kuholele esigabeni sesifo sezinso sokuphela.

Izinkinga ezingavela ku-lupus nephritis zifaka:

• Ukwehluleka okukhulu kwezinso
• Ukwehluleka kwezinso okungamahlalakhona

Shayela umhlinzeki wakho uma unegazi kumchamo wakho noma ukuvuvukala komzimba wakho.

Uma une-lupus nephritis, shayela umhlinzeki wakho uma ubona ukwehla kokukhishwa komchamo.

Ukwelapha i-lupus kungasiza ukuvimbela noma ukubambezela ukuqala kwe-lupus nephritis.

I-Nephritis - i-lupus; Isifo seLupus glomerular

• Ukwakheka kwezinso

UHahn BH, McMahon M, uWilkinson A, et al. Imikhombandlela ye-American College of Rheumatology yokuhlola, incazelo yamacala, ukwelashwa nokuphathwa kwe-lupus nephritis. I-Arthritis Care Res (eHoboken). 2012; 64 (6): 797-808. I-PMCID: 3437757 www.ncbi.nlm.nih.gov/pmc/articles/PMC3437757.

UWadhwani S, uJayne D, uRovin BH. I-Lupus nephritis. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, abahleli. I-Nephrology Yomtholampilo Ephelele. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2019: isahluko 26.