Ukushoda kweprotheni C noma uS

Ukushoda kweprotheni C noma S okuzalwa kungukushoda kwamaprotheni C noma S engxenyeni engamanzi yegazi. Amaprotheni yizinto zemvelo ezisiza ukuvimbela amahlule egazi.

Ukushoda kweprotheni C noma uS okuzalwa kuyisifo esizuzwe njengefa. Lokhu kusho ukuthi kudluliselwa emindenini. I-Congenital isho ukuthi ikhona lapho izalwa.

Lesi sifo sibanga ukujiya kwegazi okungavamile.

Umuntu oyedwa kwabangu-300 unesakhi sofuzo esisodwa esijwayelekile kanye nohlobo olulodwa olungalungile lokushoda kwamaprotheni C.

Ukushoda kwamaphrotheni S akujwayelekile kakhulu futhi kwenzeka kubantu abacishe babe ngu-1 kwabangu-20 000.

Uma unale nkinga, kungenzeka ukuthi ube namahlule egazi. Izimpawu ziyefana neze-vein thrombosis ejulile, futhi zifaka:

• Ubuhlungu noma isisa endaweni ethintekile
• Ukubomvu noma ukuvuvukala endaweni ethintekile

Umhlinzeki wezokunakekelwa kwempilo uzokwenza ukuhlolwa ngokomzimba abuze ngomlando nezimpawu zakho zezokwelapha.

Ukuhlolwa kwelabhorethri kuzokwenziwa ukuhlola amaprotheni C no-S.

Izidakamizwa ezinciphisa igazi zisetshenziselwa ukwelapha nokuvikela amahlule egazi.

Umphumela uvame ukuba muhle ngokwelashwa, kepha izimpawu zingabuya, ikakhulukazi uma kumiswa izinto zokunciphisa igazi.

Izinkinga zingafaka:

• Ukushaywa yizingane
• Ukulahlekelwa okungaphezu kokukodwa kokukhulelwa (ukukhulelwa kwesisu okuphindaphindiwe)
• Amahlule avamile emithanjeni
• I-pulmonary embolism (i-clot yegazi emithanjeni yamaphaphu)

Ezimweni ezingavamile, ukusebenzisa i-warfarin ukunciphisa igazi nokuvimbela amahlule kungadala amanxeba amancane wesikhumba nokuqina. Abantu basengozini uma bengalashwa nge-heparin yezidakamizwa ezinciphisa igazi ngaphambi kokuthatha i-warfarin.

Shayela umhlinzeki wakho uma unezimpawu zokujiya emthanjeni (ukuvuvukala nokubomvu komlenze).

Uma umhlinzeki wakho ekuxilonga ngale nkinga, kufanele uqaphele ukuvimbela amahlule ukuba akheke. Lokhu kungenzeka lapho igazi lihamba kancane emithanjeni, njengokuphumula embhedeni isikhathi eside ngesikhathi sokugula, ukuhlinzwa, noma ukuhlala esibhedlela. Kungenzeka futhi ngemuva kwendiza ende noma uhambo lwemoto.

Ukushoda kwamaprotheni S; Ukushoda kwamaprotheni C

• Ukwakheka kwegazi
• Amahlule egazi

U-Anderson JA, Hogg KE, Weitz JI. Izimo ezingenakunyakaziswa. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 140.

IPatterson JW. Iphethini yokuphendula ye-vasculopathic. Ku: Patterson JW, ed. I-Weedon's Skin Pathology. Umhla wesi-4. IPhiladelphia, PA: Elsevier; 2015: isahluko 8.