I-leukemia yeseli lezinwele

I-hairy cell leukemia (HCL) umdlavuza ongavamile wegazi. Ithinta amaseli we-B, uhlobo lweseli elimhlophe (i-lymphocyte).

I-HCL ibangelwa ukukhula okungajwayelekile kwamaseli B. Amaseli abukeka "anoboya" ngaphansi kwesibonakhulu ngoba anokuqagela okuhle okusuka ebusweni bawo.

I-HCL imvamisa iholela enanini eliphansi lamaseli ejwayelekile egazi.

Imbangela yalesi sifo ayikaziwa. Izinguquko ezithile zofuzo (ukuguquka) kwamangqamuzana omdlavuza kungaba yimbangela. Ithinta abesilisa kaningi kunabesifazane. Isilinganiso seminyaka yokuxilongwa singama-55.

Izimpawu ze-HCL zingafaka noma yikuphi okulandelayo:

• Ukulinyazwa okulula noma ukopha
• Ukujuluka okukhulu (ikakhulukazi ebusuku)
• Ukukhathala nobuthakathaka
• Ukuzizwa usuthi ngemuva kokudla inani elincane kuphela
• Ukutheleleka okuvamile kanye nemfiva
• Ubuhlungu noma ukugcwala esiswini esingenhla kwesobunxele (ubende obukhulisiwe)
• Izindlala ze-lymph ezivuvukile
• Ukwehla kwesisindo

Ngesikhathi sokuhlolwa komzimba, umhlinzeki wezokunakekelwa kwempilo angakwazi ukuzwa ubende noma isikhumba esivuvukile. Iskena se-CT esiswini noma i-ultrasound kungenziwa ukuhlola lokhu kuvuvukala.

Ukuhlolwa kwegazi okungenziwa kufaka phakathi:

• Qedela ukubalwa kwegazi (i-CBC) ukuhlola amazinga aphansi amaseli egazi amhlophe nabomvu, kanye nama-platelets.
• Ukuhlolwa kwegazi kanye nomongo wethambo ukuhlola amaseli anoboya.

Ukwelashwa kungenzeka kungadingi izigaba zokuqala zalesi sifo. Abanye abantu bangadinga ukumpontshelwa igazi ngezikhathi ezithile.

Uma ukwelashwa kuyadingeka ngenxa yezibalo eziphansi kakhulu zegazi, izidakamizwa ze-chemotherapy zingasetshenziswa.

Ezimweni eziningi, i-chemotherapy inganciphisa izimpawu iminyaka eminingi. Lapho izimpawu nezimpawu zihamba, kuthiwa usekuxolelweni.

Ukususa ubende kungathuthukisa ukubalwa kwegazi, kepha akunakwenzeka ukuthi kuselaphe lesi sifo. Ama-antibiotic angasetshenziswa ukwelapha izifo. Abantu abanezibalo eziphansi zegazi bangathola izici zokukhula futhi, mhlawumbe, nokumpontshelwa.

Iningi labantu abane-HCL bangalindela ukuhlala iminyaka eyishumi noma ngaphezulu ngemuva kokuxilongwa nokwelashwa.

Izibalo eziphansi zegazi ezibangelwa i-hairy leukemia ingaholela ku:

• Izifo
• Ukukhathala
• Ukopha ngokweqile

Shayela umhlinzeki wakho uma wopha kakhulu. Fonela futhi uma unezimpawu zokutheleleka, njengomkhuhlane oqhubekayo, ukukhwehlela, noma ukugula okuvamile.

Ayikho indlela eyaziwayo yokuvikela lesi sifo.

I-leukemic reticuloendotheliosis; HCL; I-leukemia - iseli elinoboya

• Ukufiswa komnkantsha wethambo
• I-leukemia yeseli lezinwele - umbono omncane
• Ubende obukhulisiwe

Iwebhusayithi yeNational Cancer Institute. Uhlobo lwezempilo lwe-hairy cell leukemia (PDQ).www.cancer.gov/types/leukemia/hp/hairy-cell-treatment-pdq. Kubuyekezwe ngoMashi 23, 2018. Kufinyelelwe ngoJulayi 24, 2020.

URavandi F. I-leukemia yeseli elinenwele. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 78.