Isifo seCharcot-Marie-Tooth

Isifo seCharcot-Marie-Tooth siyiqembu lezinkinga ezidluliswa emindenini ethinta izinzwa ezingaphandle kobuchopho nomgogodla. Lezi zibizwa ngokuthi izinzwa zomngcele.

ICharcot-Marie-Tooth ingesinye sezifo ezivame kakhulu ezihlobene nezinzwa ezidluliselwa emindenini (ezuzwe njengefa). Izinguquko okungenani zofuzo ezingama-40 zidala izinhlobo ezahlukahlukene zalesi sifo.

Lesi sifo siholela ekulimaleni noma ekubhujisweni kwesembozo (i-myelin sheath) ezungeze imicu yezinzwa.

Imithambo ekhuthaza ukunyakaza (ebizwa ngokuthi yimisipha yezimoto) ithinteka kakhulu. Izinzwa emilenzeni zithinteka kuqala futhi kakhulu.

Izimpawu zivame ukuqala phakathi kokukhula kobuntwana nokuba mdala. Zingafaka:

• Ukukhubazeka kwezinyawo (i-arch ephezulu kakhulu ukuya ezinyaweni)
• Ukwehla konyawo (ukungakwazi ukubamba unyawo kuvundle)
• Ukulahleka kwemisipha yomlenze ongezansi, okuholela kumathole amancane
• Ukuba ndikindiki onyaweni noma emlenzeni
• "Ukushaya" (izinyawo zishaya phansi kanzima lapho uhamba)
• Ubuthakathaka bezinqulu, imilenze, noma izinyawo

Kamuva, izimpawu ezifanayo zingavela ezingalweni nasezandleni. Lokhu kungafaka isandla esifana nozipho.

Ukuhlolwa ngokomzimba kungakhombisa:

• Kunzima ukuphakamisa unyawo nokwenza ukunyakaza kozwane (ukwehla konyawo)
• Ukuntuleka kokuzindla okulula emilenzeni
• Ukulahleka kokulawulwa kwemisipha kanye ne-atrophy (ukuncipha kwemisipha) onyaweni noma emlenzeni
• Izinyanda ezinesisindo esijiyile ngaphansi kwesikhumba semilenze

Ukuhlolwa kokuqhutshwa kwemizwa kuvame ukwenziwa ukukhomba izinhlobo ezahlukahlukene zesifo. I-nerve biopsy ingaqinisekisa ukuxilongwa.

Ukuhlolwa kofuzo kuyatholakala ezinhlotsheni eziningi zalesi sifo.

Alikho ikhambi elaziwayo. Ukuhlinzwa ngamathambo noma okokusebenza (okufana nezinsimbi noma izicathulo ezihlanganisa izicathulo zamathambo) kungenza kube lula ukuhamba.

Ukwelashwa ngokomzimba nangokomsebenzi kungasiza ekugcineni amandla emisipha futhi kuthuthukise ukusebenza okuzimele.

Isifo seCharcot-Marie-Tooth siya ngokuya siba sibi. Ezinye izingxenye zomzimba zingaba ndikindiki, futhi ubuhlungu bungaba buphakathi kobumnene bube bukhulu. Ekugcineni lesi sifo singadala ukukhubazeka.

Izinkinga zingafaka:

• Ukuthuthuka ukungakwazi ukuhamba
• Ubuthakathaka obuqhubekayo
• Ukulimala ezindaweni zomzimba ezehlile ukuzwa

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma kukhona ubuthakathaka obuqhubekayo noma ukuncipha kokuzwa ezinyaweni noma emilenzeni.

Ukwelulekwa nokuhlolwa ngofuzo kuyelulekwa uma kunomlando oqinile womndeni walesi sifo.

I-neuropathic (peroneal) eqhubekayo yemisipha ye-atrophy; Ukungasebenzi kahle kwemizwa ye-peroneal nerve; I-Neuropathy - i-peroneal (ifa); Imoto yefa ne-neuropathy yezinzwa

• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo

Katirji B. Ukuphazamiseka kwemizwa yomngcele. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 107.

I-Sarnat HB. I-neuropathies yezinzwa ezizimele. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 631.