I-Ganglioneuroblastoma

I-Ganglioneuroblastoma iyisigaxa esiphakathi esivela kwizicubu zemizwa. Isigaxa esiphakathi singesinye esiphakathi kobungozi (esikhula kancane futhi okungenakwenzeka ukuthi sisabalale) nesibulalayo (esikhula ngokushesha, esinolaka futhi esingasakazeka).

IGanglioneuroblastoma yenzeka kakhulu ezinganeni ezineminyaka emibili kuya kwemi-4 ubudala. Isimila sithinta abafana namantombazane ngokulinganayo. Kwenzeka ngokungavamile kubantu abadala. Izimila zesistimu yezinzwa zinezigaba ezihlukile zokwehlukanisa. Lokhu kuncike ekutheni amangqamuzana ezimila abukeka kanjani ngaphansi kwesibonakhulu. Ingabikezela ukuthi kungenzeka yini ukuthi isabalale noma cha.

Izicubu zeBenign mancane amathuba okusabalala. Izicubu eziyingozi zinolaka, zikhula ngokushesha, futhi zivame ukusabalala. I-ganglioneuroma ayinabungozi kangako emvelweni. I-neuroblastoma (eyenzeka ezinganeni ezineminyaka engaphezu kwengu-1 ubudala) ivame ukuba yingozi.

I-ganglioneuroblastoma ingaba sendaweni eyodwa kuphela noma ingahle isabalale, kepha imvamisa ayinalo ulaka kune-neuroblastoma. Imbangela ayaziwa.

Ngokuvamile, isigaxa singazwakala esiswini ngobumnene.

Lesi sifo singavela nakwezinye izindawo, kufaka phakathi:

• Isikhala sesifuba
• Intamo
• Imilenze

Umhlinzeki wezokunakekelwa kwempilo angenza lezi zivivinyo ezilandelayo:

• Isifiso esihle senaliti yesimila
• Ukufiswa komnkantsha we-Bone kanye ne-biopsy
• Ukuskena kwamathambo
• I-CT scan noma i-MRI scan yendawo ethintekile
• Ukuskena kwe-PET
• Iskena seMetaiodobenzylguanidine (MIBG)
• Ukuhlolwa okukhethekile kwegazi nomchamo
• I-biopsy yokuhlinzwa ukuqinisekisa ukuxilongwa

Ngokuya ngohlobo lwesimila, ukwelashwa kungabandakanya ukuhlinzwa, futhi mhlawumbe nokwelashwa ngamakhemikhali nokwelashwa ngemisebe.

Ngoba lezi zicubu azivamile, kufanele zilashwe esikhungweni esikhethekile ngochwepheshe abanolwazi nazo.

Izinhlangano ezinikeza ukwesekwa kanye nolwazi olwengeziwe:

• I-Oncology Group Yezingane - www.childrensoncologygroup.org
• I-Neuroblastoma Children's Cancer Society - www.neuroblastomacancer.org

Umbono uncike ekutheni isimila sesisabalale kangakanani, nokuthi ngabe ezinye izindawo zesimila zinamaseli omdlavuza ahlasela kakhulu.

Izinkinga ezingaba nomphumela zifaka:

• Izinkinga zokuhlinzwa, imisebe, noma i-chemotherapy
• Ukusabalala kwesimila ezindaweni ezizungezile

Shayela umhlinzeki wakho uma uzwa isigaxa noma ukukhula emzimbeni wengane yakho. Qinisekisa ukuthi izingane zithola izivivinyo ezijwayelekile njengengxenye yokunakekelwa kwazo kahle kwezingane.

UHarrison DJ, u-Ater JL. I-Neuroblastoma. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 525.

IMyers JL. I-Mediastinum. Ku: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. URosai no-Ackerman's Pathology Yokuhlinzwa. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2018: isahluko 12.