Ukuhlaziywa kwe-CSF

Ukuhlaziywa kweCerebrospinal fluid (CSF) yiqembu lezivivinyo zaselabhorethri ezikala amakhemikhali ku-cerebrospinal fluid. I-CSF iwuketshezi olucacile oluzungeze futhi luvikele ubuchopho nentambo yomgogodla. Ukuhlolwa kungabheka amaprotheni, ushukela (i-glucose), nezinye izinto.

Isampula le-CSF liyadingeka. Ukubhoboza i-lumbar, okubizwa nangokuthi umpompi womgogodla, kuyindlela ejwayelekile kakhulu yokuqoqa lesi sampula. Izindlela ezingejwayelekile zokuthatha isampula eluketshezi zifaka:

• Ukubhoboza umthombo
• Ukususwa kwe-CSF kushubhu esivele iku-CSF, njenge-shunt, i-ventricular drain, noma iphampu yezinhlungu
• Ukubhoboza okubonakalayo

Ngemuva kokuthi kuthathwe isampula, ithunyelwa elabhorethri iyohlolwa.

Udokotela wakho uzokucela ukuthi ulale phansi okungenani ihora elilodwa ngemuva kokubhoboza i-lumbar. Ungaba nekhanda ngemuva kokuqhuma kwesikhumba. Uma kwenzeka, ukuphuza iziphuzo ezine-caffeine ezifana nekhofi, itiye noma i-soda kungasiza.

Umhlinzeki wakho wokunakekelwa kwezempilo uzokutshela ukuthi ungakulungiselela kanjani ukubhoboza i-lumbar.

Ukuhlaziywa kwe-CSF kungasiza ukuthola izimo nezifo ezithile. Konke okulandelayo kungaba, kepha akuhlali njalo, kukalwa kusampula ye-CSF:

• Ama-antibody kanye ne-DNA yamagciwane ajwayelekile
• Amagciwane (kufaka phakathi lokho okubangela ugcunsula, usebenzisa ukuhlolwa kwe-VDRL)
• Ukubalwa kweseli
• I-chloride
• I-antigen ye-Cryptococcal
• Ishukela
• I-Glutamine
• I-Lactate dehydrogenase
• I-Oligoclonal banding ukubheka amaprotheni athile
• Amaprotheni ayisisekelo e-Myelin
  
• Ingqikithi yamaprotheni
• Noma ngabe kunamaseli anomdlavuza akhona
• Ingcindezi yokuvula
  

Imiphumela ejwayelekile ifaka phakathi:

• Ama-antibody kanye ne-DNA yamagciwane avamile: Akukho
• Amagciwane: Awekho amabhaktheriya akhula kusiko lebhu
• Amaseli Anomdlavuza: Awekho amaseli anomdlavuza akhona
• Ukubalwa kwamaseli: angaphansi kwamaseli ama-5 amhlophe egazi (wonke ama-mononuclear) namaseli abomvu ayi-0
• I-chloride: 110 kuya ku-125 mEq / L (110 kuya ku-125 mmol / L)
• Isikhunta: Akukho
• I-glucose: 50 kuya ku-80 mg / dL noma ku-2.77 kuya ku-4.44 mmol / L (noma ngaphezulu kwezingxenye ezimbili kwezintathu zezinga likashukela egazini)
• I-Glutamine: 6 kuya ku-15 mg / dL (410.5 kuya ku-1,026 micromol / L)
• I-Lactate dehydrogenase: ngaphansi kuka-40 U / L
• Amaqembu e-Oligoclonal: ama-0 noma ama-1 band angekho kusampula ye-serum ehambisanayo
• Amaprotheni: 15 kuya ku-60 mg / dL (0.15 kuye ku-0.6 g / L)
• Ingcindezi yokuvula: 90 to 180? Mm wamanzi
• Amaprotheni ayisisekelo e-Myelin: Ngaphansi kwe-4ng / mL

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izibonelo ezingenhla zibonisa izilinganiso ezivamile zemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Umphumela wokuhlaziya we-CSF ongajwayelekile ungaba ngenxa yezimbangela eziningi ezahlukahlukene, kufaka phakathi:

• Umdlavuza
• I-Encephalitis (njenge-West Nile ne-Eastern Equine)
• I-hepatic encephalopathy
• Ukutheleleka
• Ukuvuvukala
• I-Reye syndrome
• I-Meningitis ngenxa yamagciwane, ukhunta, isifo sofuba, noma igciwane
• I-Multiple sclerosis (MS)
• Isifo i-Alzheimer
• I-Amyotrophic lateral sclerosis (ALS)
• Pseudotumor Cerebrii
• Ingcindezi ejwayelekile i-hydrocephalus

Ukuhlaziywa koketshezi lweCerebrospinal

• I-CSF chemistry

U-Euerle BD. Ukubhoboza umgogodla nokuhlolwa koketshezi lwe-cerebrospinal. Ku: Roberts JR, Custalow CB, Thomsen TW, ama-eds. Izinqubo Zomtholampilo zikaRoberts noHedges ku-Emergency Medicine kanye ne-Acute Care. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2019: isahluko 60.

IGriggs RC, iJozefowicz RF, u-Aminoff MJ. Indlela eya esigulini esinesifo se-neurologic. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 396.

IKarcher DS, iMcPherson RA. I-Cerebrospinal, synovial, uketshezi lomzimba we-serous, nezinye izinhlobo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 29.

IRosenberg GA. I-edema yobuchopho nokuphazamiseka kokujikeleza kwe-cerebrospinal fluid. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 88.